Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CB1R Allosteric modulator 3 is a potent CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP and β-Arrestin, and can be used for the study of obesity and nicotine addiction.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 8,000 | |||
2 mg | 在庫あり | ¥ 11,500 | |||
5 mg | 在庫あり | ¥ 18,500 | |||
10 mg | 在庫あり | ¥ 32,000 | |||
25 mg | 在庫あり | ¥ 53,500 | |||
50 mg | 在庫あり | ¥ 80,000 | |||
100 mg | 在庫あり | ¥ 118,500 |
説明 | CB1R Allosteric modulator 3 is a potent CB1R modulator.CB1R Allosteric modulator 3 inhibits cAMP and β-Arrestin, and can be used for the study of obesity and nicotine addiction. |
ターゲット&IC50 | cAMP:0.018 μM (EC50), β-Arrestin:1.241 μM (EC50) |
In vitro | At a duration of 30 minutes and concentrations ranging from 0.10 nM to 10 μM, CB1R Allosteric modulator 3 (compound 44) exhibits potent inhibition of cAMP and β-Arrestin, with EC50 values of 0.018 μM and 1.241 μM, respectively [1].Due to the presence of small lipophilic functional groups on the ortho-position of the GAT211 site-III phenyl ring, CB1R Allosteric modulator 3 can enhance CB1R ago-PAM activity [1]. |
分子量 | 376.84 |
分子式 | C22H17ClN2O2 |
CAS No. | 2633686-36-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (212.29 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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CB1R Allosteric modulator 3 2633686-36-7 GPCR/G Protein cAMP Cannabinoid Receptor Inhibitor inhibitor inhibit