Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs.
説明 | CJ-13,610 hydrochloride is an orally active nonredox-type inhibitor of 5-LOX and can be used in studies about the prevention of untoward pathophysiological effects of LTs. |
In vitro | In intact human polymorphonuclear leukocytes (PMNL), challenged with the Ca(2+)-ionophore A23187, CJ-13,610 hydrochloride potently suppressed 5-LOX product formation with an IC50 of 70 nM. In transfected HeLa cells, CJ-13,610 hydrochloride only slightly discriminated between phosphorylatable wild-type 5-LOX and a 5-LOX mutant that lacks phosphorylation sites[2]. |
分子量 | 429.96 |
分子式 | C22H24ClN3O2S |
CAS No. | 179420-27-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (104.66 mM)
You can also refer to dose conversion for different animals. 詳細
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CJ-13,610 hydrochloride 179420-27-0 Metabolism Lipoxygenase CJ 13,610 hydrochloride CJ13,610 hydrochloride CJ-13,610 Hydrochloride Inhibitor inhibitor inhibit