Powder: -20°C for 3 years | In solvent: -80°C for 1 year
11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenase
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 13,000 | |||
5 mg | 在庫あり | ¥ 32,000 | |||
10 mg | 在庫あり | ¥ 51,000 | |||
25 mg | 在庫あり | ¥ 86,000 | |||
50 mg | 在庫あり | ¥ 127,000 | |||
100 mg | 在庫あり | ¥ 181,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 33,000 |
説明 | 11-Keto-beta-boswellic acid, a novel Nrf2 activator, and a selective 5-lipoxygenase (5-LOX) inhibitor; it exerts dose dependent cardioprotective effect manifested by dose-dependent reduction in serum lactate dehydrogenase |
In vitro | A total of ten transformed compounds were isolated and purified, and their chemical structures were characterized as 7β-hydroxy-11-keto-β-boswellic acid; 7β, 15α±-dihydroxy-11-keto-β-boswellic acid ; 7β, 16β-dihydroxy-11-keto-β-boswellic acid; 7β, 16α±-dihydroxy-11-keto-β-boswellic acid; 7β, 22β-dihydroxy-11-keto-β-boswellic acid; 7β, 21β-dihydroxy-11-keto-β-boswellic acid; 7β, 20β-dihydroxy-11-keto-β-boswellic acid; 7β, 30-dihydroxy-11-keto-β-boswellic acid; 3α±, 7β-dihydroxy-11-oxours-12-ene-24, 30-dioic acid and 3α±, 7β-dihydroxy-30-(2-hydroxypropanoyloxy)-11-oxours-12-en-24-oic acid by various spectroscopic methods. The biotransformation processes include hydroxylation, oxidation and esterification. Primary structure-activity relationships (SAR) of inhibitory effects on NO production in RAW 264.7 macrophage cells are discussed[1] |
植物由来 |
別名 | 11-Keto-beta-boswellic acid |
分子量 | 470.68 |
分子式 | C30H46O4 |
CAS No. | 17019-92-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5 mg/mL (47.8 mM)
You can also refer to dose conversion for different animals. 詳細
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11-Keto-beta-boswellic acid 17019-92-0 GPCR/G Protein Metabolism NF-Κb Lipoxygenase Leukotriene Receptor NF-κB 11-Keto-β-boswellic acid LOX Inhibitor 11 Keto beta boswellic acid Nuclear factor-κB Nuclear factor-kappaB 11Ketobetaboswellic acid 11-Keto-beta-boswellic acid inhibit 11-Keto-b-boswellic acid inhibitor