Powder: -20°C for 3 years | In solvent: -80°C for 1 year
eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)
説明 | eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM) |
ターゲット&IC50 | Src:< 0.5 nM) |
In vivo | eCF506, the first small molecule with subnanomolar IC50 for SRC that requires 3 orders of magnitude greater concentration to inhibit ABL.?eCF506 exhibits excellent water solubility, an optimal DMPK profile and oral bioavailability, halts SRC-associated neuromast migration in zebrafish embryos without inducing life-threatening heart defects, and inhibits SRC phosphorylation in tumor xenografts in mice. |
分子量 | 510.63 |
分子式 | C26H38N8O3 |
CAS No. | 1914078-41-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 62.5 mg/mL (122.40 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
eCF506 1914078-41-3 Angiogenesis Tyrosine Kinase/Adaptors Src eCF-506 Inhibitor eCF 506 inhibit inhibitor