Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HBDDE is a selective model inhibitor of the isoenzymes PKCα and PKCγ with IC 50 s of 43 μM and 50 μM, respectively.HBDDE has a higher affinity for PKCα/PKCγ than the PKCδ, PKCβI, and PKCβII isoenzymes.HBDDE is a derivative of ellagic acid, which induces apoptosis in neuronal cells. HBDDE is a derivative of ellagic acid and induces apoptosis in neuronal cells.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 80,500 |
5 mg | 在庫あり | ¥ 190,000 |
10 mg | 在庫あり | ¥ 259,500 |
25 mg | 在庫あり | ¥ 365,000 |
50 mg | 在庫あり | ¥ 454,500 |
100 mg | 在庫あり | ¥ 574,000 |
500 mg | 在庫あり | ¥ 1,124,500 |
説明 | HBDDE is a selective model inhibitor of the isoenzymes PKCα and PKCγ with IC 50 s of 43 μM and 50 μM, respectively.HBDDE has a higher affinity for PKCα/PKCγ than the PKCδ, PKCβI, and PKCβII isoenzymes.HBDDE is a derivative of ellagic acid, which induces apoptosis in neuronal cells. HBDDE is a derivative of ellagic acid and induces apoptosis in neuronal cells. |
ターゲット&IC50 | PKCα:43 μM (IC50), PKCγ:50 μM (IC50) |
In vitro | HBDDE (50 μM; 5 h; Cerebellar granule cells) leads to a substantial reduction in cell viability by approximately 70%. Additionally, HBDDE demonstrates a notable augmentation in caspase-3 activity.[1] |
分子量 | 338.31 |
分子式 | C16H18O8 |
CAS No. | 154675-18-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.5 mg/mL (13.3 mM)
H2O: 0.9 mg/mL (2.7 mM)
Ethanol: 0.9 mg/mL (2.7 mM)
You can also refer to dose conversion for different animals. 詳細
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HBDDE 154675-18-0 Apoptosis Chromatin/Epigenetic Cytoskeletal Signaling PKC Inhibitor inhibitor inhibit