Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tafamidis meglumine (Fx-1006A) is a Potent and Selective Transthyretin Kinetic Stabilizer That Inhibits the Amyloid Cascade
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 11,000 | |||
10 mg | 在庫あり | ¥ 18,500 | |||
25 mg | 在庫あり | ¥ 35,500 | |||
50 mg | 在庫あり | ¥ 55,000 | |||
100 mg | 在庫あり | ¥ 85,000 | |||
500 mg | 在庫あり | ¥ 199,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,000 |
説明 | Tafamidis meglumine (Fx-1006A) is a Potent and Selective Transthyretin Kinetic Stabilizer That Inhibits the Amyloid Cascade |
ターゲット&IC50 | TTR:2.7-3.2 μM (EC50) |
In vitro | Tafamidis binds selectively and with negative cooperativity (K(d)s ~2 nM and ~200 nM) to the two normally unoccupied thyroxine-binding sites of the tetramer, and kinetically stabilizes TTR.?Patient-derived amyloidogenic variants of TTR, including kinetically and thermodynamically less stable mutants, are also stabilized by tafamidis binding[1]. |
別名 | Fx-1006A |
分子量 | 503.33 |
分子式 | C21H24Cl2N2O8 |
CAS No. | 951395-08-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12.5 mg/mL (24.83 mM)
You can also refer to dose conversion for different animals. 詳細
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tafamidis meglumine 951395-08-7 Others Fx-1006A Inhibitor Tafamidis inhibit inhibitor