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リグナン類

The lignans are a group of chemical compounds possessing a steroid-like chemical structure found in plants, particularly in flax seed. Lignans are one of the major classes of phytoestrogens, which are estrogen-like chemicals and also act as antioxidants. The other classes of phytoestrogens are the isoflavones, and coumestans. Traditionally, health benefits attributed to lignans have included a lowered risk of heart disease, menopausal symptoms, osteoporosis and breast cancer.

Cat. No. 製品名 CAS No. Purity Chemical Structure
TN1036 Gomisin D 60546-10-3 98.20%
Gomisin D is a natural product
TN1757 Hypophyllanthin 33676-00-5 98.39%
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
TN2071 Picropodophyllone 477-48-5 98.49%
Picropodophyllone is one of the lignans from the roots of D. aurantiocaulis and D. pleianthum.
TN2080 Pinoresinol 487-36-5 98.67%
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, ...
T5S0483 (-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside 136997-64-3 98.7%
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) is a lignan glycosides from the bark of Albizzia myr...
T3S1089 Phillygenin 487-39-8 98.7%
1. Phillyrin, (+)-Phillygenin (Sylvatesmin), and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values.
T3836 Eudesmin 526-06-7 98.86%
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 ...
T5S2283 Sesamolin 526-07-8 98.89%
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 ac...
T3855 Tracheloside 33464-71-0 98.95%
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μ...
T6S1918 Schisantherin B 58546-55-7 99.06%
1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hep...
T10390 Asperphenamate 63631-36-7 99.07%
Asperphenamate is a fungal metabolite of Aspergillus flatiipes. The IC50s for T47D cells, MDA-MB-231 cells, and HL-60 cells are 92.3 μM, 96.5 μM, and 97.9 μM. As...
TN1087 Deoxypodophyllotoxin 19186-35-7 99.21%
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammat...
T11680 Isoasatone A 67451-73-4 99.21%
Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity.
TN1390 Angeloylgomisin Q 72561-28-5 99.23%
Angeloylgomisin Q is a natural product from Schizandra chinensis BAILL.
TN4675 Nortrachelogenin 34444-37-6 99.27%
Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl as...
T2S0029 4'-Demethylpodophyllotoxin 40505-27-9 99.27%
4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines.
T8188 Podophyllotoxone 477-49-6 99.31%
Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.
T6S1917 Schisandrol B 58546-54-6 99.32%
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated...
T6943 Picropodophyllin 477-47-4 99.41%
Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulate...
T3662 Eleutheroside E 39432-56-9 99.43%
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus ...
Gomisin D
TN1036
Gomisin D is a natural product
Hypophyllanthin
TN1757
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice.
Picropodophyllone
TN2071
Picropodophyllone is one of the lignans from the roots of D. aurantiocaulis and D. pleianthum.
Pinoresinol
TN2080
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, ...
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside
T5S0483
(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) is a lignan glycosides from the bark of Albizzia myr...
Phillygenin
T3S1089
1. Phillyrin, (+)-Phillygenin (Sylvatesmin), and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(5) values.
Eudesmin
T3836
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 ...
Sesamolin
T5S2283
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 ac...
Tracheloside
T3855
Tracheloside significantly decreases the activity of alkaline phosphatase (IC50: 0.31 μg/ml), a level of inhibition comparable to that of tamoxifen (IC50: 0.43 μ...
Schisantherin B
T6S1918
1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hep...
Asperphenamate
T10390
Asperphenamate is a fungal metabolite of Aspergillus flatiipes. The IC50s for T47D cells, MDA-MB-231 cells, and HL-60 cells are 92.3 μM, 96.5 μM, and 97.9 μM. As...
Deoxypodophyllotoxin
TN1087
Deoxypodophyllotoxin shows cytotoxic , antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammat...
Isoasatone A
T11680
Isoasatone A is a natural product isolated from the plant Heterotropa takaoi M., with anti-insect activity.
Angeloylgomisin Q
TN1390
Angeloylgomisin Q is a natural product from Schizandra chinensis BAILL.
Nortrachelogenin
TN4675
Nortrachelogenin ((-)-Wikstromol), which can be extracted from Partrinia scabiosaefolia, has antifungal activity and induces membrane disruption and cysteinyl as...
4'-Demethylpodophyllotoxin
T2S0029
4'-Demethylpodophyllotoxin is isolated from the herb of Dysosma pleiantha (Hance) Woodson with remarkable cytotoxic potential in diverse cancer cell lines.
Podophyllotoxone
T8188
Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.
Schisandrol B
T6S1917
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated...
Picropodophyllin
T6943
Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulate...
Eleutheroside E
T3662
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus ...
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