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リグナン類

The lignans are a group of chemical compounds possessing a steroid-like chemical structure found in plants, particularly in flax seed. Lignans are one of the major classes of phytoestrogens, which are estrogen-like chemicals and also act as antioxidants. The other classes of phytoestrogens are the isoflavones, and coumestans. Traditionally, health benefits attributed to lignans have included a lowered risk of heart disease, menopausal symptoms, osteoporosis and breast cancer.

Cat. No. 製品名 CAS No. Purity Chemical Structure
TN2197 Secoisolariciresinol 29388-59-8 99.51%
Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation...
TN7089 Alashinol G 58139-12-1 99.53%
Alashinol G ((-)-Carinol) is isolated from the stem bark of Syringa pinnatifolia, a Mongolian folk medicine with anti-myocardial ischaemic effects.
T3415 Secoisolariciresinol diglucoside 158932-33-3 99.54%
Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglu...
T3S0027 Picropodophyllotoxin 17434-18-3 99.57%
Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insuli...
T10383 Asatone 38451-63-7 99.68%
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK...
T3904 Gomisin J 66280-25-9 99.69%
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic en...
T2S0531 Pinoresinol dimethyl ether 29106-36-3 99.75%
Pinoresinol dimethyl ether, a non-phenolic furan lignan isolated from the bark of Magnolia kobus, exhibits neuroactivity. It stimulates upstream MAPK, PKC, and P...
T5S1959 (-)-Asarinin 133-04-0 99.79%
(-)-Asarinin (Eleutheroside B4) shows antibacterial activity.
TN4660 Niranthin 50656-77-4 99.8%
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitiv...
T5S2178 Fargesin 31008-19-2 99.82%
1. Fargesin ((+/-)-Fargesin) as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Far...
TN1116 Schisandrone 98619-25-1 99.84%
Schisandrone (Arisantetralone C) is a 4-aryltetrahydrofuran lignan extracted from the dried fruit of Schisandra chinensis.
TN1038 Galgravin 528-63-2 99.88%
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid...
TN2070 Picropodophyllol 3811-15-2 99.9%
Picropodophyllol is a natural product isolated from the roots of Dysosma versipellis
T0132 Etoposide 33419-42-0 99.93%
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide ha...
TN1018 Angeloylgomisin H 66056-22-2 99.95%
Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.
T6S1543 Dehydrodiisoeugenol 2680-81-1 99.97%
1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated w...
T3S1541 Rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan 178740-32-4 99.98%
Rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydrofuran is a chemical component found in the fruit of nutmeg.
T6S1930 Schisanhenol 69363-14-0 99.99%
1. Schisanhenol (Schizanhenol) can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidati...
TN2062 Phyllanthin 10351-88-9 99.99%
Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.
TN4374 Kaerophyllin 75590-33-9 98%
Kaerophyllin ( (-)-Kaerophylin), a lignan isolated from the traditional Chinese medicine Chai Hu, inhibits activation of hepatic stellate cells by hepatocyte apo...
Secoisolariciresinol
TN2197
Secoisolariciresinol is an enterolignan precursor, it has antioxidant, and estrogen-like activities, it can significantly suppress triglyceride (TG) accumulation...
Alashinol G
TN7089
Alashinol G ((-)-Carinol) is isolated from the stem bark of Syringa pinnatifolia, a Mongolian folk medicine with anti-myocardial ischaemic effects.
Secoisolariciresinol diglucoside
T3415
Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglu...
Picropodophyllotoxin
T3S0027
Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insuli...
Asatone
T10383
Asatone, an active component isolated from Radix et Rhizoma Asari, has an anti-inflammatory effect via activation of NF-κB and downregulation of p-MAPK (ERK, JNK...
Gomisin J
T3904
Gomisin J is a natural product and have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic en...
Pinoresinol dimethyl ether
T2S0531
Pinoresinol dimethyl ether, a non-phenolic furan lignan isolated from the bark of Magnolia kobus, exhibits neuroactivity. It stimulates upstream MAPK, PKC, and P...
(-)-Asarinin
T5S1959
(-)-Asarinin (Eleutheroside B4) shows antibacterial activity.
Niranthin
TN4660
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitiv...
Fargesin
T5S2178
1. Fargesin ((+/-)-Fargesin) as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Far...
Schisandrone
TN1116
Schisandrone (Arisantetralone C) is a 4-aryltetrahydrofuran lignan extracted from the dried fruit of Schisandra chinensis.
Galgravin
TN1038
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid...
Picropodophyllol
TN2070
Picropodophyllol is a natural product isolated from the roots of Dysosma versipellis
Etoposide
T0132
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide ha...
Angeloylgomisin H
TN1018
Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.
Dehydrodiisoeugenol
T6S1543
1. Dehydrodiisoeugenol has anti-inflammatory activity. (1). Dehydrodiisoeugenol inhibited the expression of the COX-2 in RAW264.7 murine macrophages stimulated w...
rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydro-furan
T3S1541
Rel-(8R,8'R)-Dimethyl-(7S,7'R)-bis(3,4-methylenedioxyphenyl)tetrahydrofuran is a chemical component found in the fruit of nutmeg.
Schisanhenol
T6S1930
1. Schisanhenol (Schizanhenol) can protect against adriamycin induced heart mitochondrial toxicity. 2. Schisanhenol has antioxidative effect on human LDL oxidati...
Phyllanthin
TN2062
Phyllanthin is widely used as hepatoprotective and antigenotoxic and inhibit function of P-gp.
Kaerophyllin
TN4374
Kaerophyllin ( (-)-Kaerophylin), a lignan isolated from the traditional Chinese medicine Chai Hu, inhibits activation of hepatic stellate cells by hepatocyte apo...
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