The terpenoids, sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes. Most are multicyclic structures with oxygen-containing functional groups. About 60% of known natural products are terpenoids.
Plant terpenoids are used for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes. Well-known terpenoids include citral, menthol, camphor, salvinorin A in the plant Salvia divinorum, the cannabinoids found in cannabis, ginkgolide and bilobalide found in Ginkgo biloba, and the curcuminoids found in turmeric and mustard seed.
Many terpenes have biological activities and are used for the treatment of human diseases. The worldwide sales of terpene-based pharmaceuticals in 2002 were approximately US $12 billion. Among these pharmaceuticals, the anticancer drug Taxol and the antimalarial drug Artimesinin are two of the most renowned terpene-based drugs. All terpenoids are synthesized from two five-carbon building blocks. Based on the number of the building blocks, terpenoids are commonly classified as monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), and sesterterpenes (C25). These terpenoids display a wide range of biological activities against cancer, malaria, inflammation, and a variety of infectious diseases (viral and bacterial). In last two decades, natural-product bioprospecting from the marine environment has resulted in hundreds of terpenoids with novel structures and interesting bioactivities, with more to be discovered in the future. There is no doubt that more terpenoid-based clinical drugs will become available and will play a more significant role in human disease treatment in the near future.
Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
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T5S1131 | Ganoderic acid C6 | 105742-76-5 | 99.92% |
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1. Ganoderic acid C6 has antinociceptive activity. | ||||
T19882 | Bryonolic acid | 24480-45-3 | 99.93% |
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Bryonolic acid (20-epi-Bryonolic acid), a triterpenoid extracted from Sandoricum indicum, possesses immunomodulatory, anti-inflammatory, antioxidant and anticanc... | ||||
T2829 | Isoalantolactone | 470-17-7 | 99.94% |
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Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells. | ||||
TN1059 | Ganoderic acid B | 81907-61-1 | 99.95% |
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Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards th... | ||||
T3S0208 | Hederagenin 28-O-beta-D-glucopyranosyl ester | 53931-25-2 | 99.95% |
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Hederagenin-28-beta-D-glucopyranoside, a triterpene saponin isolated from Ilex cornuta, protects cardiac myocytes against H2O2-induced damage. | ||||
T3819 | Ursolic acid acetate | 7372-30-7 | 99.95% |
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Ursolic acid acetate (Acetylursolic acid) has cytotoxic activity, antimalarial activity, antitumor and anticancer activities. Acetylursolic acid has NO productio... | ||||
T0687 | Simvastatin | 79902-63-9 | 99.95% |
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Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cho... | ||||
T4S1718 | Punicalin | 65995-64-4 | 99.95% |
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Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-depende... | ||||
T5739 | Paederosidic acid | 18842-98-3 | 99.96% |
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Paederosidic acid has significant anti-tumor, anticonvulsant and sedative effects. Paederosidic acid increases brain gamma-aminobutyric acid and decreases glutam... | ||||
T4962 | Zingibroside R1 | 80930-74-1 | 99.96% |
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Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity. | ||||
T3S1513 | (20R)-Protopanaxadiol | 7755-01-3 | 99.97% |
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1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial micr... | ||||
T3332 | Isosteviol | 27975-19-5 | 99.97% |
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Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside ... | ||||
T4S0675 | Polygalasaponin V | 162857-65-0 | 99.98% |
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Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia... | ||||
T3918 | Ginsenoside Rb3 | 68406-26-8 | 99.98% |
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Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits ... | ||||
T5775 | Cauloside F | 60451-47-0 | 99.98% |
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Cauloside F is a triterpenoid saponin found in Clematis akebioides. | ||||
T8200 | Ginkgolide K | 153355-70-5 | 99.98% |
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Ginkgolide K induces protective autophagy through the AMPK/mTOR/ULK1 signalling pathway. It possesses neuroprotective activity. | ||||
TN1006 | Tirucallol | 514-46-5 | 99.98% |
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Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action re... | ||||
TN2167 | Rutaevin | 33237-37-5 | 99.99% |
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Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflamm... | ||||
TQ0073 | Andropanolide | 869807-57-8 | 98% |
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Andropanolide is a dipterocarbon from Andrographis paniculata with anti-HIV, antimalarial and anticancer activities and inhibits Lipopolysaccharides (LPS)-stimul... | ||||
TN4183 | Hardwickiic acid | 1782-65-6 | 98% |
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Hardwickiic acid ((-)-Hardwikiic acid) is a natural compound derived from Pulicaria gnaphalodes and is an anti-injury receptor compound. hardwickiic acid blocks ... |