The terpenoids, sometimes called isoprenoids, are a large and diverse class of naturally occurring organic chemicals derived from terpenes. Most are multicyclic structures with oxygen-containing functional groups. About 60% of known natural products are terpenoids.
Plant terpenoids are used for their aromatic qualities and play a role in traditional herbal remedies. Terpenoids contribute to the scent of eucalyptus, the flavors of cinnamon, cloves, and ginger, the yellow color in sunflowers, and the red color in tomatoes. Well-known terpenoids include citral, menthol, camphor, salvinorin A in the plant Salvia divinorum, the cannabinoids found in cannabis, ginkgolide and bilobalide found in Ginkgo biloba, and the curcuminoids found in turmeric and mustard seed.
Many terpenes have biological activities and are used for the treatment of human diseases. The worldwide sales of terpene-based pharmaceuticals in 2002 were approximately US $12 billion. Among these pharmaceuticals, the anticancer drug Taxol and the antimalarial drug Artimesinin are two of the most renowned terpene-based drugs. All terpenoids are synthesized from two five-carbon building blocks. Based on the number of the building blocks, terpenoids are commonly classified as monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), and sesterterpenes (C25). These terpenoids display a wide range of biological activities against cancer, malaria, inflammation, and a variety of infectious diseases (viral and bacterial). In last two decades, natural-product bioprospecting from the marine environment has resulted in hundreds of terpenoids with novel structures and interesting bioactivities, with more to be discovered in the future. There is no doubt that more terpenoid-based clinical drugs will become available and will play a more significant role in human disease treatment in the near future.
Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
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TQ0248 | Alisol F | 155521-45-2 | 99.89% |
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Alisol F is a natural product from Alisma plantago-aquatica Linn and has many activities. | ||||
T5S0168 | Atractylenolide II | 73069-14-4 | 99.89% |
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1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic/apoptotic effects may via p... | ||||
TN2755 | 2-Desoxy-4-epi-pulchellin | 122872-03-1 | 99.89% |
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2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with ... | ||||
T2763 | Panaxadiol | 19666-76-3 | 99.9% |
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Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng. | ||||
T3S1896 | Lindenenol | 26146-27-0 | 99.9% |
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Lindenenol (Linderene) is isolated from Radix linderae and has antioxidant and antibacterial effects. | ||||
TMS0879 | Asiaticoside B | 125265-68-1 | 99.9% |
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Asiaticoside B is a triterpene glycoside isolated from Actaea asiatica. It has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines. | ||||
T5756 | Hastatoside | 50816-24-5 | 99.9% |
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Hastatoside and verbenalin are major sleep-promoting components of V. officinalis. Hastatoside has anti-inflammatory activity. | ||||
TN1854 | Lasiodin | 28957-08-6 | 99.90% |
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Lasiodin (Lasiokaurin) is a diterpene compound from the plant Camellia sinensis that inhibits the proliferation of NPC cells. Lasiodin has antioxidant, antitumor... | ||||
T4S0931 | Pseudolaric acid A | 82508-32-5 | 99.91% |
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Pseudolaric acid A (NSC 615487) and -B can inhibit the growth of particular cell type. | ||||
T5S1981 | Alpha-Cyperone | 473-08-5 | 99.91% |
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1. alpha-Cyperone (α-Cyperone) is a promising inhibitor of Hla production by S. aureus and protects lung cells from this bacterium. 2. alpha-Cyperone significant... | ||||
T6S2247 | Alismoxide | 87701-68-6 | 99.91% |
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1. Alismoxide ((+)-Alismoxide) has anti-inflammatory effects. | ||||
T5S0527 | Rhodojaponin III | 26342-66-5 | 99.91% |
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1. Rhodojaponin III has antifeedant and oviposition deterrence effects against many kinds of insects, BdorCSP2 of B. dorsalis could be involved in chemoreception... | ||||
T6S0619 | Pachymic acid | 29070-92-6 | 99.91% |
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Pachymic acid (3-O-Acetyltumulosic acid) is a natural product, and inhibits Akt and ERK signaling pathways. | ||||
T2808 | Bilobalide | 33570-04-6 | 99.91% |
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Bilobalide ((-)-Bilobalide), a bioactive from Gingko Biloba, is active on hypoxia-induced alterations. | ||||
TN1494 | Cimicifugoside H-1 | 163046-73-9 | 99.91% |
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Cimicifugoside H1 shows the protective function to cerebral neuron during cerebral ischemia. | ||||
T0433 | Artesunate | 88495-63-0 | 99.91% |
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Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and m... | ||||
T5708 | LUPENONE | 1617-70-5 | 99.92% |
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Lupenone is a natural product isolated from Rhizoma Musae and has good anti-diabetic activity,and has anti-inflammatory activity.lupenone were potent PTP1B inhib... | ||||
TN2296 | Vinaginsenoside R4 | 156009-80-2 | 99.92% |
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Vinaginsenoside R4 was isolated from the leaves of hydroponically grown ginseng. It inhibits melanin biosynthesis and enhances pigmentation in zebrafish without ... | ||||
T3917 | Protopanaxatriol | 1453-93-6 | 99.92% |
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Protopanaxatriol (20(R)-APPT), a major ginseng constituent, is a novel PPARγ antagonist. | ||||
T2P2806 | Hederacolchiside A1 | 106577-39-3 | 99.92% |
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Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the paras... |