Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

カタログ番号	製品名 / Synonyms	Species	Expression System
TMPK-00181	PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated	Mouse	HEK293 Cells
TMPK-00181	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp...
TMPK-00180	PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated PD-1 Protein, Human, Recombinant (aa 25-167, hFc & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00180	Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's resp...
TMPK-00179	B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated B7-1 Protein, Human, Recombinant (aa 35-242, His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00179	Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal ne...
TMPK-00178	B7-1 Protein, Human, Recombinant (His & Avi) B7-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00178	Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal ne...
TMPK-00177	LAIR1 Protein, Human, Recombinant (His & Avi) LAIR1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00177	LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig sup...
TMPK-00172	B7-H4 Protein, Human, Recombinant (His & Avi) B7-H4 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00172	B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas i...
TMPK-00166	PD-L2 Protein, Human, Recombinant (His & Avi) PD-L2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00166	PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T...
TMPK-00112	CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated CTLA-4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00112	CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune ...
TMPK-00062	CD160 Protein, Human, Recombinant (His & Avi) CD160 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
TMPK-00062	CD160 (also Natural killer cell receptor BY55) is a 27 ‑ 30 kDa member of the Ig superfamily. In human, it is expressed principally on nonmyeloid hematopoietic c...
TMPJ-01455	Galectin-9 Protein, Human, Recombinant (His) Galectin-9 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPJ-01455	Galectin-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 49 KDa and the accession ...
TMPJ-01421	LAG-3 Protein, Cynomolgus, Recombinant (hFc) LAG-3 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
TMPJ-01421	LAG-3 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 90 KDa and the accession num...
TMPJ-01247	BTN2A2 Protein, Human, Recombinant (hFc) BTN2A2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPJ-01247	BTN2A2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-80 KDa and the accession numb...
TMPJ-01246	BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293 Cells
TMPJ-01246	BTN2A2 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 55-80 KD...
TMPJ-01242	CD160 Protein, Mouse, Recombinant (His) CD160 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPJ-01242	CD160 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 20-25 KDa and the accession nu...
TMPJ-01199	BTN2A1 Protein, Human, Recombinant (His) BTN2A1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPJ-01199	Butyrophilin 2A1 (BTN2A1) is an approximately widely expressed and variably glycosylated type I transmembrane glycoprotein. Mature human Butyrophilin 2A1 consisi...
TMPJ-01086	CD244 Protein, Mouse, Recombinant (His) CD244 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPJ-01086	Natural killer cell receptor 2B4 (2B4/CD244)is a 66 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 protein family. SLAM family proteins ha...
TMPJ-00959	B7-2 Protein, Rabbit, Recombinant (His) B7-2 Protein, Rabbit, Recombinant (His)	Rabbit	HEK293 Cells
TMPJ-00959	B7-2 Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 38-70 KDa and the accession nu...
TMPJ-00958	B7-1 Protein, Rabbit, Recombinant (His) B7-1 Protein, Rabbit, Recombinant (His)	Rabbit	HEK293 Cells
TMPJ-00958	Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily which plays key, yet distinct roles in the activation of ...
TMPJ-00950	CD96 Protein, Human, Recombinant (mFc) CD96 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
TMPJ-00950	CD96 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 120 KDa and the accession number ...
TMPJ-00949	CD96 Protein, Human, Recombinant (hFc) CD96 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPJ-00949	CD96 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 110-160 KDa and the accession numb...