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Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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Species
Canine (8)
Cavia porcellus (1)
Cynomolgus (60)
Human (196)
Marmoset (1)
Mouse (80)
Rabbit (2)
Rat (25)
Rhesus (33)
Expression System
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (5)
HEK293 Cells (380)
P. pastoris (Yeast) (1)
Tag
Avi (6)
C-6xHis (25)
C-6xHis-Avi (3)
C-Avi (4)
C-Avi-6xHis (5)
C-Avi-His (2)
C-Fc (1)
C-Flag (3)
C-GST (1)
C-His (129)
C-His-Avi (40)
C-hFc (101)
C-hFc-6xHis (2)
C-hFc-Avi (21)
C-hFc-His (1)
C-mFc (16)
C-rFc (2)
His (9)
N-6xHis-Flag (1)
N-8xHis (1)
N-Flag (7)
N-GST (2)
N-His (1)
N-His-Avi (7)
N-hFc (2)
N-hFc-Flag (1)
Tag Free (12)
hFc (3)
カタログ番号 製品名 / Synonyms Species Expression System
TMPJ-00698 BTNL2 Protein, Mouse, Recombinant (His)
BTNL2 Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I tran...
TMPJ-00659 Galectin-9 Protein, Mouse, Recombinant (GST)
Galectin-9 Protein, Mouse, Recombinant (GST)
Mouse E. coli
Galectin-9 Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 58 KDa and the accession...
TMPJ-00641 B7-2 Protein, Rhesus macaque, Recombinant (His)
B7-2 Protein, Rhesus macaque, Recombinant (His)
Rhesus HEK293 Cells
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the acce...
TMPJ-00640 CTLA-4 Protein, Cavia porcellus, Recombinant (His)
CTLA-4 Protein, Cavia porcellus, Recombinant (His)
Cavia porcellus P. pastoris (Yeast)
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 ...
TMPJ-00638 PD-L1 Protein, Cynomolgus, Recombinant (His)
PD-L1 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
PD-L1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-40 KDa and the accessi...
TMPJ-00637 PD-L1 Protein, Cynomolgus, Recombinant (hFc)
PD-L1 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
PD-L1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 73 KDa and the accession num...
TMPJ-00636 CTLA-4 Protein, Cynomolgus, Recombinant (His)
CTLA-4 Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
CTLA-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 17-25 KDa and the access...
TMPJ-00635 CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
CTLA-4 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-60 KDa and the accession...
TMPJ-00632 B7-2 Protein, Cynomolgus, Recombinant (hFc)
B7-2 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession ...
TMPJ-00630 B7-1 Protein, Cynomolgus, Recombinant (hFc)
B7-1 Protein, Cynomolgus, Recombinant (hFc)
Cynomolgus HEK293 Cells
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-pr...
TMPJ-00629 TIGIT Protein, Cynomolgus, Recombinant (His)
TIGIT Protein, Cynomolgus, Recombinant (His)
Cynomolgus HEK293 Cells
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT ...
TMPJ-00627 CD160 Protein, Rhesus macaque, Recombinant (His)
CD160 Protein, Rhesus macaque, Recombinant (His)
Rhesus HEK293 Cells
CD160 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16-30 KDa and the acc...
TMPJ-00626 CD160 Protein, Rhesus macaque, Recombinant (hFc)
CD160 Protein, Rhesus macaque, Recombinant (hFc)
Rhesus HEK293 Cells
CD160 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the access...
TMPJ-00624 TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)
Marmoset HEK293 Cells
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and ...
TMPJ-00614 CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
Rhesus HEK293 Cells
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral mem...
TMPJ-00613 CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc)
Rhesus HEK293 Cells
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accessi...
TMPJ-00599 TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
Human HEK293 Cells
Hepatitis A virus cellular receptor 2(HAVCR2)is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein ...
TMPJ-00556 B7-2 Protein, Human, Recombinant (His)
B7-2 Protein, Human, Recombinant (His)
Human HEK293 Cells
B7-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 57-66 KDa and the accession num...
TMPJ-00555 B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
Human HEK293 Cells
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 55-80 K...
TMPJ-00551 Siglec-9 Protein,Human, Recombinant(aa 18-348, His)
Siglec-9 Protein,Human, Recombinant(aa 18-348, His)
Human HEK293 Cells
Siglec-9 Protein,Human, Recombinant(aa 18-348, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-90 KDa and the ...
BTNL2 Protein, Mouse, Recombinant (His)
TMPJ-00698
Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I tran...
Galectin-9 Protein, Mouse, Recombinant (GST)
TMPJ-00659
Galectin-9 Protein, Mouse, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 58 KDa and the accession...
B7-2 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00641
B7-2 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-90 KDa and the acce...
CTLA-4 Protein, Cavia porcellus, Recombinant (His)
TMPJ-00640
CTLA-4 Protein, Cavia porcellus, Recombinant (His) is expressed in P. pastoris yeast expression system with C-6xHis tag. The predicted molecular weight is 18-40 ...
PD-L1 Protein, Cynomolgus, Recombinant (His)
TMPJ-00638
PD-L1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-40 KDa and the accessi...
PD-L1 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00637
PD-L1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 73 KDa and the accession num...
CTLA-4 Protein, Cynomolgus, Recombinant (His)
TMPJ-00636
CTLA-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 17-25 KDa and the access...
CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00635
CTLA-4 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-60 KDa and the accession...
B7-2 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00632
B7-2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-100 KDa and the accession ...
B7-1 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00630
Cynomologous Cluster of Differentiation 80, also called B7-1, is a member of cell surface immunoglobulin superfamily.It is expressed on the surface of antigen-pr...
TIGIT Protein, Cynomolgus, Recombinant (His)
TMPJ-00629
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT ...
CD160 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00627
CD160 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 16-30 KDa and the acc...
CD160 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00626
CD160 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the access...
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His)
TMPJ-00624
TIM-3/KIM-3/HAVCR2 Protein, Marmoset, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 30-45 KDa and ...
CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
TMPJ-00614
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily. Mouse CD47 is an integral mem...
CD47 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00613
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-90 KDa and the accessi...
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc & His)
TMPJ-00599
Hepatitis A virus cellular receptor 2(HAVCR2)is a single-pass type I membrane protein and it contains 1 Ig-like V-type (immunoglobulin-like) domain. The protein ...
B7-2 Protein, Human, Recombinant (His)
TMPJ-00556
B7-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 57-66 KDa and the accession num...
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00555
B7-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 55-80 K...
Siglec-9 Protein,Human, Recombinant(aa 18-348, His)
TMPJ-00551
Siglec-9 Protein,Human, Recombinant(aa 18-348, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-90 KDa and the ...
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