Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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カタログ番号	製品名 / Synonyms	Species	Expression System
TMPJ-00183	PD-L1 Protein, Human, Recombinant (Flag) PD-L1 Protein, Human, Recombinant (Flag)	Human	Human Cells
TMPJ-00183	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin ...
TMPJ-00182	PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	Human Cells
TMPJ-00182	CD274, also known as B7-H1 or programmed death ligand 1 (PD-L1), is a 40 kD type I transmembrane protein and a member of the B7 family within the immunoglobulin ...
TMPJ-00181	PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
TMPJ-00181	Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-...
TMPJ-00179	LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated	Human	Human Cells
TMPJ-00179	Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear c...
TMPJ-00176	B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated B7-H4 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	Human Cells
TMPJ-00176	B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellula...
TMPJ-00175	B7-H4 Protein, Rhesus macaque, Recombinant (hFc) B7-H4 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus macaque	Human Cells
TMPJ-00175	B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas,...
TMPJ-00174	TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His) TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-193, His)	Mouse	Human Cells
TMPJ-00174	T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of...
TMPJ-00173	TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His) TIM-3/KIM-3/HAVCR2 Protein, Mouse, Recombinant (aa 20-191, His)	Mouse	Human Cells
TMPJ-00173	T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of...
TMPJ-00129	BTLA Protein, Human, Recombinant (His) BTLA Protein, Human, Recombinant (His)	Human	Human Cells
TMPJ-00129	B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induc...
TMPJ-00108	CTLA-4 Protein, Human, Recombinant (GST) CTLA-4 Protein, Human, Recombinant (GST)	Human	Human Cells
TMPJ-00108	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA enc...
TMPJ-00107	CTLA-4 Protein, Human, Recombinant (Flag) CTLA-4 Protein, Human, Recombinant (Flag)	Human	Human Cells
TMPJ-00107	Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA enc...
TMPJ-00063	CD160 Protein, Human, Recombinant (hFc) CD160 Protein, Human, Recombinant (hFc)	Human	Human Cells
TMPJ-00063	CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine...