Neurotrophins are a family of proteins that induce the survival, development, and function of neurons. They belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins that promote the survival of neurons are known as neurotrophic factors. Neurotrophic factors are secreted by target tissue and act by preventing the associated neuron from initiating programmed cell death-allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to form neurons.
Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain (for example, the hippocampus) retain the ability to grow new neurons from neural stem cells, a process known as neurogenesis. Neurotrophins are chemicals that help to stimulate and control neurogenesis.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
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TMPY-04069 | Neurotrophin 3 Protein, Human, Recombinant
Neurotrophin 3 Protein, Human, Recombinant
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Human | E. coli |
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and different... | |||
TMPY-02792 | GDNF Protein, Human, Recombinant (HEK293)
GDNF Protein, Human, Recombinant (HEK293)
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Human | HEK293 |
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neur... | |||
TMPY-02202 | TNF alpha Protein, Rat, Recombinant
TNF alpha Protein, Rat, Recombinant
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Rat | E. coli |
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule ... | |||
TMPY-01133 | Latent TGF beta 1 Protein, Human, Recombinant (His)
Latent TGF beta 1 Protein, Human, Recombinant (His)
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Human | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... | |||
TMPJ-01469 | NGF Protein, Human, Recombinant (E. colli)
NGF Protein, Human, Recombinant (E. colli)
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Mouse | E.coli |
NGF is the first member discovered in the Neurotrophin family, which includes brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4... | |||
TMPJ-01468 | Pro-Beta NGF Protein, Human, Recombinant
pro-Beta NGF Protein, Human, Recombinant
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Human | E.coli |
The precursor form of the nerve growth factor (proNGF) like its mature form is characterized by the cystin knot motif consisting of three cystine bridges, wherea... | |||
TMPY-06985 | NGF Protein, Human, Recombinant (HEK293)
NGF Protein, Human, Recombinant (HEK293)
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Human | HEK293 |
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large ... | |||
TMPY-06985 | NGF Protein, Human, Recombinant (HEK293)
NGF Protein, Human, Recombinant (HEK293)
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Human | HEK293 |
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large ... | |||
TMPY-06985 | NGF Protein, Human, Recombinant (HEK293)
NGF Protein, Human, Recombinant (HEK293)
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Human | HEK293 |
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large ... | |||
TMPY-06985 | NGF Protein, Human, Recombinant (HEK293)
NGF Protein, Human, Recombinant (HEK293)
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Human | HEK293 |
Nerve growth factor (NGF) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF protein was identified as a large ... | |||
TMPJ-00779 | TNF alpha Protein, Rabbit, Recombinant
TNF alpha Protein, Rabbit, Recombinant
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Rabbit | E. coli |
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TN... | |||
TMPJ-00261 | TGF beta 2 Protein, Mouse/Rat, Recombinant
TGF beta 2 Protein, Mouse/Rat, Recombinant
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Mouse,Rat | Human Cells |
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deleti... | |||
TMPJ-00258 | TGF beta 2 Protein, Human, Recombinant
TGF beta 2 Protein, Human, Recombinant
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Human | Human Cells |
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular fun... | |||
TMPJ-00254 | TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
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Human,Mouse,Rat | Human Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted a... | |||
TMPJ-00249 | TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
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Human | Human Cells |
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and ... | |||
TMPJ-00135 | BDNF Protein, Human/Murine/Rat, Recombinant
BDNF Protein, Human/Murine/Rat, Recombinant
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Human,Mouse,Rat | E. coli |
Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF, NT-3 and NT-4, B... | |||
TMPY-06247 | TGF beta 3 Protein, Human, Recombinant (hFc)
TGF beta 3 Protein, Human, Recombinant (hFc)
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Human | HEK293 |
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 41.2 kDa. Accession number: P10600-1 | |||
TMPY-01073 | GDF-15 Protein, Human, Recombinant (hFc)
GDF-15 Protein, Human, Recombinant (hFc)
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Human | HEK293 |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertr... | |||
TMPY-04727 | GDF-15 Protein, Human, Recombinant (His)
GDF-15 Protein, Human, Recombinant (His)
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Human | Yeast |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertr... | |||
TMPY-05510 | BDNF Protein, Mouse, Recombinant (His)
BDNF Protein, Mouse, Recombinant (His)
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Mouse | HEK293 |
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in hea... |