Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different mammalian isoforms (TGF-β 1 to 3, HGNC symbols TGFB1, TGFB2, TGFB3) and many other signaling proteins. TGFB proteins are produced by all white blood cell lineages. Activated TGF-β complexes with other factors to form a serine/threonine kinase complex that binds to TGF-β receptors. TGF-β receptors are composed of both type 1 and type 2 receptor subunits. After the binding of TGF-β, the type 2 receptor kinase phosphorylates and activates the type 1 receptor kinase that activates a signaling cascade. This leads to the activation of different downstream substrates and regulatory proteins. TGF-β also plays a crucial role in stem cell differentiation as well as T-cell regulation and differentiation. Because of its role in immune and stem cell regulation and differentiation, it is a highly researched cytokine in the fields of cancer, auto-immune diseases, and infectious disease.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
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TMPY-02792 | GDNF Protein, Human, Recombinant (HEK293)
GDNF Protein, Human, Recombinant (HEK293)
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Human | HEK293 |
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neur... | |||
TMPY-01133 | Latent TGF beta 1 Protein, Human, Recombinant (His)
Latent TGF beta 1 Protein, Human, Recombinant (His)
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Human | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... | |||
TMPJ-01471 | Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
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Human/Mouse/Rat | Human Cells |
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfami... | |||
TMPJ-00261 | TGF beta 2 Protein, Mouse/Rat, Recombinant
TGF beta 2 Protein, Mouse/Rat, Recombinant
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Mouse,Rat | Human Cells |
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deleti... | |||
TMPJ-00258 | TGF beta 2 Protein, Human, Recombinant
TGF beta 2 Protein, Human, Recombinant
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Human | Human Cells |
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular fun... | |||
TMPJ-00254 | TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
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Human,Mouse,Rat | Human Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted a... | |||
TMPJ-00249 | TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
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Human | Human Cells |
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and ... | |||
TMPY-06247 | TGF beta 3 Protein, Human, Recombinant (hFc)
TGF beta 3 Protein, Human, Recombinant (hFc)
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Human | HEK293 |
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 41.2 kDa. Accession number: P10600-1 | |||
TMPY-01073 | GDF-15 Protein, Human, Recombinant (hFc)
GDF-15 Protein, Human, Recombinant (hFc)
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Human | HEK293 |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertr... | |||
TMPY-04727 | GDF-15 Protein, Human, Recombinant (His)
GDF-15 Protein, Human, Recombinant (His)
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Human | Yeast |
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertr... | |||
TMPY-00500 | Latent TGF beta 1 Protein, Mouse, Recombinant (His)
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
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Mouse | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... | |||
TMPY-02638 | TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
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Human,Rhesus,Cynomolgus,Canine | CHO |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... | |||
TMPY-04211 | Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... | |||
TMPY-00608 | TGF beta 1 Protein, Rat/Mouse, Recombinant
TGF beta 1 Protein, Rat/Mouse, Recombinant
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Mouse,Rat | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... | |||
TMPY-03945 | Latent TGF beta 1 Protein, Rat, Recombinant (His)
Latent TGF beta 1 Protein, Rat, Recombinant (His)
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Rat | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... | |||
TMPY-06970 | GDNF Protein, Human, Recombinant
GDNF Protein, Human, Recombinant
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Human | E. coli |
Glial cell line-derived neurotrophic factor(GDNF) is an important member of the GDNF family of ligands(GFL). The GDNF family of ligands is comprised by four neur... | |||
TMPY-06355 | Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His)
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Human | HEK293 |
Latent TGF beta 1 & GARP Heterotrimer Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 108.72 kDa. Access... | |||
TMPY-05521 | Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
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Human | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... | |||
TMPY-05314 | TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
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Mouse | HEK293 |
TGF beta 2 (Transforming growth factor beta 2), an extracellular glycosylated protein, which belongs to the TGF-beta family. TGF-beta regulates key mechanisms of... | |||
TMPY-05313 | Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
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Mouse | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the r... |