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T37735 |
Stearoyl-L-carnitine chloride
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C18 Carnitine,Stearoylcarnitine chloride |
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Stearoyl-L-carnitine chloride (Acylcarnitine C18:0) is a long-chain acylcarnitine found in the cerebellum that inhibits GlyT2 and is an important component in the study of lipid metabolism. |
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T38253 |
Lauroyl-L-carnitine (chloride)
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Lauroyl-L-carnitine Hydrochloride |
Others
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Lauroyl-L-carnitine (chloride) (Lauroyl-L-carnitine Hydrochloride), an acylcarnitine and surfactant, has been used to permeate porcine intestinal cells to deliver the polar fluorescent probe fluorescent yellow. |
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T37359 |
Myristoyl-L-carnitine chloride
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L-Myristoylcarnitine chloride |
Endogenous Metabolite
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Myristoyl-L-carnitine chloride (L-Myristoylcarnitine chloride) is one of the body's metabolites implicated in inherited metabolic disorders.Tetradecanoylcarnitine is a potential marker for the study of diabetes mellitus ... |
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T26551 |
Acetyl-L-carnitine
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RO 447190,L-Acetylcarnitine,LAC,L-O-Acetylcarnitine,ALCAR,Acetyl L carnitine |
Endogenous Metabolite
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Acetyl-L-carnitine(RO 447190) is an amino acid that crosses the blood-brain barrier and is often used as a dietary supplement for neuroinflammation.Acetyl-L-carnitine is neuroprotective and can be used in the study of ne... |
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T37407 |
Arachidonoyl-L-carnitine (chloride)
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C20:4 Carnitine,Arachidonoyl-L-carnitine (chloride) |
Others
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Carnitine facilitates the transport of fatty acids into the mitochondria to be used in fatty acid metabolism. It does so by accepting acyl groups from fatty acids complexed with coenzyme A, which yields esterified carnit... |
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T19528 |
Propionylcarnitine
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Propionyl carnitine |
Others
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Propionylcarnitine (Propionyl carnitine) is a widely used dietary supplement that has been associated with glaucoma and does it ruptu |
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T38267 |
Valeryl-L-carnitine (chloride)
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Valeryl-L-carnitine (chloride),L-Valerylcarnitine |
Others
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Valeryl-L-carnitine is a short-chain acylcarnitine and a derivative of L-carnitine . Valeryl-L-carnitine levels increase in the serum of rhesus monkeys following exposure to 7 and 10 Gray units (Gy) of ionizing radiation... |
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T37453 |
Butyryl-L-carnitine (chloride)
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Others
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Butyryl-L-carnitine is a butyrate ester of carnitine. It is an inhibitor of intestinal transporters, blocking carnitine uptake by the carnitine transporter and glycine transport by the amino acid transporter in human ret... |
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T36050 |
Linoleoyl-L-carnitine (chloride)
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Others
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Linoleoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Hepatic levels of linoleoyl-L-carnitine are increased following high-dose (200 mg/kg) administration of isoniazid in mice. |
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T38232 |
Heptanoyl-L-carnitine (chloride)
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Others
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Heptanoyl-L-carnitine is a medium-chain acylcarnitine and derivative of L-carnitine . |
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T37245 |
Palmitoyl-D-carnitine (chloride)
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Others
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Palmitoyl-D-carnitine is a long-chain acylcarnitine, an isomer of palmitoyl-L-carnitine , and the D enantiomer of palmitoyl-DL-carnitine . It inhibits carnitine palmitoyltransferase with a Ki value of 2.1 mM for 14C-palm... |
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T36098 |
Isovaleryl-L-carnitine (chloride)
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Others
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Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocyt... |
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T36663 |
Decanoyl-L-carnitine (chloride)
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Others
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Decanoyl-L-carnitine is an ester derivative of L-carnitine . It increases the formation of C24 fatty acid intermediates, as well as docosapentaenoic and docosahexaenoic acid in rat hepatocytes. |
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T38233 |
Hexanoyl-L-carnitine (chloride)
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Others
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Hexanoyl-L-carnitine is a medium-chain acylcarnitine. It has been used in the synthesis of acylcarnitine benzyl esters.1
1.Gong, X.-w., Li, J.-p., Wu, J.-f., et al.Synthesis of carnitine benzyl esters as prodrugsJ. Chem.... |
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T37641 |
Trans-2-Octenoyl-L-carnitine
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Others
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trans-2-Octenoyl-L-carnitine is a synthetic carnitine.1It has been used as a standard for the detection of carnitines in human urine.
1.Yang, S., Minkler, P., and Hoppel, C.cis-3,4-methylene-heptanoylcarnitine: Character... |
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T37640 |
Trans-2-Hexadecenoyl-L-carnitine
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Others
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trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1].
[1]. Pengxiang She, et al. Leucine and protein metabolism in obese Zucker rats. PLoS One. 2013;8(3):e59443. |
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T37516 |
[(3R)-3-Hydroxydodecanoyl]-L-carnitine
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Others
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[(3R)-3-Hydroxydodecanoyl]-L-carnitine is an endogenous metabolite[1].
[1]. Hunter WG, et al. Metabolomic Profiling Identifies Novel Circulating Biomarkers of Mitochondrial Dysfunction Differentially Elevated in Heart Fa... |
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T83872 |
Oleoyl-L-carnitine chloride
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L-Carnitine oleoyl ester,L-Octadecanoylcarnitine,C18:1 Carnitine,CAR 18:1 |
Others
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Oleoyl-L-carnitine, a long-chain acylcarnitine, acts as a selective inhibitor of glycine transporter 2 (GlyT2; IC50 = 340 nM) while demonstrating significantly lesser affinity for GlyT1 (IC50 = >10,000 nM). Elevated plas... |
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T20193 |
L-Carnitine tartrate
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L-Carnitine L-tartrate,Carnipure tartrate |
Others
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L-Carnitine tartrate is a Carnitine/ Constituent of striated muscle and liver. It is used to treatment of hyperlipoproteinemias. |
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T12356 |
Palmitoylcarnitine
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Palmitoyl DL-carnitine |
Endogenous Metabolite
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Palmitoylcarnitine (Palmitoyl DL-carnitine) is a mitochondrial fatty acid oxidation intermediate that acts as a surfactant. |
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T13810 |
Palmitoylcarnitine chloride
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Palmitoyl DL-carnitine chloride |
PKC
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Palmitoylcarnitine chloride (Palmitoyl DL-carnitine chloride) is a mitochondrial fatty acid oxidation intermediate that mediates intralipid cardioprotection.Palmitoylcarnitine chloride eliminates colorectal cancer cell s... |
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T21655 |
(±)-Acetylcarnitine chloride
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Acetyl dl-carnitine chloride |
AChR
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(±)-Acetylcarnitine chloride (Acetyl dl-carnitine chloride) is a weak cholinergic agonist with neuroprotective properties and can be used in studies of neuritis. |
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T1182 |
Levocarnitine propionate hydrochloride
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Propionyl-L-carnitine hydrochloride,L-Propionylcarnitine chloride,ST-261 |
Histamine Receptor
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Levocarnitine propionate hydrochloride (ST-261) is used for the treatment of the deterioration of renal function, congestive heart failure, intermittent claudication, and other diseases. |
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T22484 |
(±)-Propionylcarnitine chloride
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Propionyl-DL-carnitine chloride |
Endogenous Metabolite
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(±)-Propionylcarnitine chloride (Propionyl-DL-carnitine chloride) is a mixture of short-chain acylcarnitines used as a dietary supplement for the study of chronic diabetes. |
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T84847 |
D-Carnitine
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Others
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D-Carnitine, an orally available isomer of the essential nutrient L-carnitine, facilitates the transport of long-chain fatty acids into the mitochondrial matrix for beta-oxidation. Additionally, D-Carnitine exhibits anti... |
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T37299 |
L-Palmitoylcarnitine chloride
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Palmitoyl-L-carnitine chloride |
ATPase
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L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO mode... |
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T73766 |
Isobutyryl-L-carnitine chloride
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Others
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Isobutyryl-L-carnitine chloride is a product of the acyl-CoA dehydrogenases [1] . |
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T78569 |
CPT2
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Carnitine palmitoyltransferase 2 |
Apoptosis
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Carnitine palmitoyltransferase 2 (CPT2), an enzyme involved in fatty acid oxidation, serves as a prognostic biomarker for colorectal cancer (CRC). Overexpression of CPT2 activates phosphorylated p53, enhancing its expres... |
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T24042 |
Erucyllevocarnitine
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Erucyl-L-carnitine,L-Erucoylcarnitine |
Others
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Erucyllevocarnitine is an inhibitor of palmityl-carnitine oxidation. |
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T29598 |
Acetylcarnitine arginyl amide
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ST-857,acetyl-L-carnitine arginine amide |
Others
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Acetylcarnitine arginyl amide is able to stimulate neurite outgrowth in a manner similar to that elicited by nerve growth factor (NGF). Neurite induction by this molecule requires de novo mRNA synthesis and is independen... |
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T1182L |
Levocarnitine propionate
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L-Propionylcarnitine,ST261,ST 261,Propionyl-L-carnitine,ST-261 |
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Propionylcarnitine is present in high abundance in the urine of patients with Methylmalonyl-CoA mutase (MUT) deficiency. |
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T4535 |
Etomoxir sodium salt
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(R)-Etomoxir sodium salt,Na salt,Etomoxir |
Apoptosis
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Others
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Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis. Etomoxir sodium salt has antitumor activity. |
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T6586 |
Mildronate dihydrate
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Meldonium,Mildronate |
Others
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Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption. |
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T3268 |
Mildronate
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Kvaterin,Meldonium,Quaterin |
Hydroxylase
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Mildronate (Meldonium) is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption. |
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T11978 |
McN3716
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NSC359682,Methyl palmoxirate |
Mitochondrial Metabolism
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CPT
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T36416 |
N1-Acetylspermine trihydrochloride
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N1-Acetylspermine (hydrochloride) |
Endogenous Metabolite
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N1-Acetylspermine trihydrochloride is a monoacetylated derivative of spermine which is an endogenous polyamine. N1-Acetylspermine trihydrochloride can be used in studies about the uptake of the anticancer polyamine anal... |
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T4535L |
Etomoxir
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(R)-(+)-Etomoxir |
Antioxidant
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CPT
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Etomoxir is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that inhibits fatty acid oxidation by inhibiting CPT-1a and inhibits palmitate oxidation in humans, rats, and guinea pigs. Etomoxir has an inhibitory eff... |
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T68196 |
Aminocarnitine
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Others
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Aminocarnitine is an inhibitor of fatty acid oxidation that acts as a hypoglycemic and antiketogenic compound. It alters lipidic metabolism by inhibiting carnitine acetyltransferase (CAT) and carnitine palmitoyltransfera... |
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T13113 |
Teglicar
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Others
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Teglicar is a selective and reversible liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1) inhibitor. |
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T68445 |
Clomoxir
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Others
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Clomoxir is a carnitine palmitoyltransferase I inhibitor that was under development as an antiarrhythmic and antidiabetic. |
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T68618 |
S-(-)-Etomoxir
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Others
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S-(-)-Etomoxir is an inhibitor of carnitine palmitoyltransferase A (CPT1) -- a molecule required for the oxidation of long-chain acyl CoA esters. |
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T36842 |
Isobutyryl Coenzyme A (sodium salt)
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Others
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Isobutyryl coenzyme A (isobutyryl-CoA) is a short-chain branched acyl CoA. Isobutyryl-CoA is a substrate for isobutyryl-CoA dehydrogenase (IBDH) in the catabolism of valine and an intermediate in the synthesis of isobuty... |
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T83767 |
4-Hydroxyphenylglyoxylic Acid
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UK 22486 |
Others
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4-Hydroxyphenylglyoxylic acid, an active metabolite of the prodrug oxfenicine, functions as an inhibitor of carnitine palmitoyltransferase 1 (CPT1). It effectively inhibits CPT1 in isolated rat liver mitochondria at conc... |
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T74038 |
Palmitoyl coenzyme A lithium
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Others
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Palmitoyl coenzyme A lithium, an acyl-CoA thioester, facilitates transport into the mitochondrial matrix through the carnitine shuttle system for β-oxidation. Additionally, it serves as a substrate in sphingosine biosynt... |
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T73829 |
Malonyl CoA
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Others
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Malonyl CoA serves as a substrate in fatty acid biosynthesis while inhibiting fatty acid oxidation. It also acts as a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1 [1] [2]. |
