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カタログ番号 | 製品名 | 別名 | ターゲット |
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T77701 | FL118 | FL 118,FL-118,10,11-(Methylenedioxy)-20(S)-camptothecin | Survivin |
FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt/β-catenin s... | |||
T27113 | Camptothecin-20(S)-O-propionate | CZ 48,CZ48,CZ-48 | |
CZ-48 is a DNA topoisomerase inhibitor. | |||
T74494 | Antitumor agent-63 | ||
Antitumor Agent-63 (Compound 40), a 20 (S)-O-linked camptothecin (CPT) glycoconjugate, serves as a non-toxic antitumor agent showing high stability and very weak direct inhibition of topoisomerase I (Topo I) [1], demonst... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1123 | Camptothecin | NSC-100880,Campathecin,(S)-(+)-Camptothecin,CPT | Apoptosis , Influenza Virus , Topoisomerase , Antibiotic , Antifungal |
Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity. Camptothecin has antitumor activity and induces apoptosis. | |||
T3S1957 | 9-amino-CPT | Aminocamptothecin,9-amino-2(S)-camptothecin,9-Aminocamptothecin | Topoisomerase |
9-amino-CPT (Aminocamptothecin) is an inhibitor of topoisomerase I with potent anticancer activity. | |||
T0486L | Irinotecan Hydrochloride | Camptothecin 11 hydrochloride,CPT-11 hydrochloride | Topoisomerase , Autophagy |
Irinotecan Hydrochloride (CPT-11 hydrochloride) is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active metabolite 7-ethyl-10-hydroxy-camptoth... |