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T11511 |
Guanosine-5'-triphosphate disodium salt
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5'-GTP disodium salt |
Others
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Endogenous Metabolite
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Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and an energy source for translation and other important cellular processes. |
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T7606 |
Guanosine 5'-diphosphate disodium salt
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5'-GDP-Na2 |
Endogenous Metabolite
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Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway. |
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T38449 |
Guanosine 5'-triphosphate-5'-adenosine
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GpppA,Guanosine 5'-triphosphate-5'-adenosine |
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Guanosine 5'-triphosphate-5'-adenosine, known as a 5′ cap analog, serves as a fluorescent substrate analog. |
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T40721 |
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine
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N7-Methyl-guanosine-5'-triphosphate-5'-adenosine,m7GpppA |
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N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog employed in the process of in vitro RNA transcription. |
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T36740 |
Guanosine 5’-diphosphate (sodium salt hydrate)
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Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR... |
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T10178 |
Guanosine 5'-triphosphate trisodium salt hydrate
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5'-GTP trisodium salt hydrate |
Others
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5'-GTP trisodium salt hydrate, an activator of the signal-transducing G proteins, serves as a precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA. |
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T72120 |
Guanosine 5'-diphosphate sodium
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GDP sodium |
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Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel and serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin i... |
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T40921 |
5'-O-DMT-2'-O-iBu-N-Bz-Guanosine
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5'-O-DMT-2'-O-iBu-N-Bz-Guanosine,5'-O-DMT-2'-O-TBDMS-ibu-rG |
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5'-O-DMT-2'-O-iBu-N-Bz-Guanosine could be used for silyl protection of ribonucleosides. |
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T40192 |
DGTP
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2'-Deoxyguanosine-5'-triphosphate |
Nucleoside Antimetabolite/Analog
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DNA/RNA Synthesis
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dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP. |
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T83820 |
TNP-GTP sodium
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TNP-Guanosine 5'-triphosphate |
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TNP-GTP, a fluorescent derivative of guanosine 5'-triphosphate (GTP), essential for protein synthesis and gluconeogenesis, exhibits an emission peak at 552 nm when excited at 410 nm in water. Its fluorescence intensity i... |
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TNU1202 |
3’,5’-TIPS-N-PAc-Guanosine
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3',5'-TIPS-N-PAc-Guanosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open. |
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T75264 |
7-Methyl-guanosine-5'-triphosphate sodium
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7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium, a guanosine 5'-phosphate derivative, serves as a potent inhibitor of cap-dependent translation, with its sodium phosphorothioate analog enhancing its efficacy [1]. |
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T74135 |
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
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N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1]. |
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T83834 |
Sp-Guanosine-5'-O-(1-thiotriphosphate) sodium
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Sp-GTP-α-S,GTPαS(Sp),GTPαS(A) |
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Sp-Guanosine-5'-O-(1-thiotriphosphate) (Sp-GTP-α-S), an isomer of the sulfur-containing nucleotide derivative GTP-α-S, demonstrates the ability to bind tubulin and facilitate microtubule assembly in cell-free assays at a... |
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T75191 |
2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium
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2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium), a purine nucleoside analog, exhibits extensive antitumor properties, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the i... |
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T64537 |
Guanosine 5′-diphospho-β-L-fucose sodium salt
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GDP-β-L-fucose is a metabolite in plant and animal. It used for microbe agglutination assay and agglutination inhibition assay. GDP-β-L-fucose is formed by the oxidation-reduction and epimerization of GDP-R-D-mannose in ... |
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T67464 |
2′,3′,5′-Tri-O-acetyl Guanosine
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2′,3′,5′-Tri-O-acetyl Guanosine is a useful organic compound for research related to life sciences. The catalog number is T67464 and the CAS number is 6979-94-8. |
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TNU1656 |
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine
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N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine is a useful organic compound for research related to life sciences. The catalog number is TNU1656 and the CAS number is 2382942-31-4. |
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TNU1082 |
2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt
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2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium salt is a useful organic compound for research related to life sciences and the catalog number is TNU1082. |
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TNU1390 |
N2-iso-Butyroyl-5’-O-DMT-3’-O-(methoxyethyl)guanosine
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N2-iso-Butyroyl-5'-O-DMT-3'-O-(methoxyethyl)guanosine is a Nucleoside Derivative - 3'-Modified nucleoside; Protected nucleoside w/NH2/OH open. |
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TNU1657 |
N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite
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N2-iBu-5’-O-DMTr-2’-O-hexadecanyl guanosine 3’-CED phosphoramidite is a useful organic compound for research related to life sciences. The catalog number is TNU1657 and the CAS number is 2382942-32-5. |
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TNU1408 |
2’,3’,5’-Tri-O-acetyl-6-S-methyl-6-thio-guanosine
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Nucleoside Derivatives - 6-Modified purine nucleosides; Protected nucleosides w/NH2/OH open |
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TNU1383 |
N2-iso-Butyroyl-5’-O-(4,4’-dimethoxytrityl)-3’-O-Methyl guanosine
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N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-Methyl guanosine is a Nucleoside Derivative - 3'-Modified nucleoside; Protected nucleoside w/NH2/OH open. |
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TNU1187 |
N2-iso-Butyroyl-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-guanosine-3’-(4-nitrophenoxyl)butanedioate
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N2-iso-Butyroyl-2’-deoxy-5’-O-(4,4’-dimethoxytrityl)-guanosine-3’-(4-nitrophenoxyl)butanedioate is a useful organic compound for research related to life sciences and the catalog number is TNU1187. |
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T0467 |
Sildenafil citrate
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UK-92480 citrate |
Apoptosis
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PDE
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Autophagy
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Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertensio... |
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T37636 |
2'-Deoxyguanosine 5'-monophosphate disodium
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5′-dGMP disodium |
Endogenous Metabolite
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2'-Deoxyguanosine 5'-monophosphate disodium (5'-dGMP disodium) is a nucleic acid guanosine triphosphate (GTP) derivative that serves as an oxidizable target and can be used in the formation of polycomplexes with other co... |
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T77570 |
AP-C2
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PKA
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AP-C2 is a potent small molecule guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII) inhibitor with a pIC50 of 5.2 for cGKII. |
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T1398 |
Tadalafil
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Cialis,IC-351 |
Apoptosis
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PDE
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Tadalafil (IC-351) is a carboline-based compound with vasodilatory activity. Tadalafil selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGM... |
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T23411L |
T-0156
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T 0156 |
PDE
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Parasite
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T-0156 is a novel, potent and selective phosphodiesterase type 5 inhibitor that inhibits the hydrolysis of cyclic guanosine monophosphate (cGMP) with low affinity for PDE6, PDE1, PDE2, PDE3 and PDE4. |
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T60500 |
AP-C5
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Parasite
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AP-C5 is a compound with selective inhibition of guanosine 3',5' cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), with a Pic50 value of 7.2 for cGMP, and can be used in the study of diarrheal diseases. |
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T0096 |
Vardenafil
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Vivanza,Levitra,Vardenafil hydrochloride |
PDE
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T24771 |
SCH-336
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SCH336,SCH 336 |
Cannabinoid Receptor
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SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100 times more selective to CB2 receptor than CB1. SCH-336 red... |
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T69593 |
Sildenafil nitrate
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Sildenafil nitrate is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP). |
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T11400 |
Gisadenafil besylate
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UK 369003-26 |
Others
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Gisadenafil besylate (UK 369003-26) is a specific, orally active phosphodiesterase 5 (PDE5) inhibitor ,prevents degradation of cyclic guanosine monophosphate (cGMP), with an IC50 of 3.6 nM . |
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T14659 |
Bis-propargyl-PEG6
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Others
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Bis-propargyl-PEG6 is a polyethylene glycol (PEG) derivative commonly employed as a PEG-based PROTAC linker during the synthesis of PROTACs. Its application includes the generation of polymer-linked multimers of guanosin... |
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T14660 |
Bis-propargyl-PEG7
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Others
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Bis-propargyl-PEG7 is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs). It is particularly employed for the synthesis of polymer-linked multimers of guanosine... |
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T36944 |
Ara-G
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Nucleoside Antimetabolite/Analog
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Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate... |
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T21803 |
Guanylyl Imidodiphosphate
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Guanylyl Imidodiphosphate trisodium (Guanosine 5'-[β,γ-imido]triphosphate), a non-hydrolysable GTP analogue, activates ADP-ribosylation factor (ARF) and strongly stimulates adenylate cyclase. It is utilized in protein sy... |
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T82990 |
AP-C4
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AP-C4 is a selective inhibitor targeting guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 5.2. Conversely, AP-C3 does not inhibit cGKII-mediated anion secretion... |
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T83814 |
8-Bromoguanosine-5'-O-triphosphate sodium
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8-bromo GTP |
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8-Bromoguanosine-5'-O-triphosphate, a derivative of guanosine 5'-triphosphate (GTP) - the energy substrate for protein synthesis and gluconeogenesis, acts as an inhibitor of the E. coli GTPase FtsZ with an inhibition con... |
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T83818 |
Isoguanosine-5'-O-triphosphate sodium
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2-Hydroxyadenosine 5’-triphosphate,2-hydroxy ATP,isoGTP |
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Isoguanosine-5'-O-triphosphate, an isomer of guanosine 5'-triphosphate (GTP) and a phosphorylated derivative of crotonoside, does not promote microtubule assembly like GTP. At a concentration of 2 mM, it hampers transcri... |
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T82991 |
AP-C3
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AP-C3 is a potent inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 value of 6.3 and demonstrating only weak inhibition of cGKII-dependent anion secretion [1... |
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T63246 |
BMS-566419
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BMS-566419 is an acridinone-based inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH), a key enzyme for the de novo synthesis of guanosine nucleotides. BMS-566419 has clinical utility in the study of graft reject... |
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T82989 |
AP-C6
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AP-C6 is a potent inhibitor of guanosine 3',5'-cyclic monophosphate (cGMP)-dependent protein kinase II (cGKII), exhibiting a pIC50 of 6.5. It inhibits human cGKII activity in vitro in a concentration-dependent manner and... |
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T83810 |
3'-Amino-3'-deoxyguanosine-5'-O-triphosphate sodium
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3'-amino-dGTP |
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3'-Amino-3'-deoxyguanosine-5'-O-triphosphate (3'-amino-dGTP), an amine-modified nucleotide, effectively terminates RNA strand synthesis as catalyzed by RNA polymerase in E. coli. This compound has also been utilized in c... |
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T73609 |
Ribonuclease T1
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Ribonuclease T1 (Rnase T1), widely utilized in biochemical research, is an endonuclease targeting single-stranded RNA. It cleaves the phosphodiester bond between 3'-guanosine residues and adjacent nucleoside 5'-OH groups... |
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T63776 |
PDE1-IN-4
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PDE1-IN-4 is a potent and selective inhibitor of PDE1 (phosphodiesterase-1), acting on PDE1C (IC50: 10 nM), PDE1A (IC50: 145 nM) and PDE1B (IC50: 354 nM). PDE1-IN-4 regulates cAMP (3′,5′-cyclic adenosine monophosphate) a... |
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T38297 |
Ribavirin-13C5
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Ribavirin-13C5 |
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Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to a... |
