T37075 |
CB2R PAM
|
2244579-87-9
|
98%
|
|
CB2R PAM is an orally active cannabinoid type 2 receptor (CB2Rs) positive mutational modulator that enhances CP 55940 and 2-Arachidonylglycerol-stimulated [35S]G...
|
T7316 |
LY2828360
|
1231220-79-3
|
98%
|
|
LY2828360 is a cannabinoid (CB) receptor 2 agonist (Ki = 40.3 nM). It selectively activates CB2 over CB1 in a GTPγS binding assay (EC50s = 20.1 and >100,000 nM, ...
|
TN3575 |
(±)-Cannabichromene
|
20675-51-8
|
98%
|
|
Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 ...
|
T23097 |
O-1602
|
317321-41-8
|
98%
|
|
O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatment of...
|
T6527 |
GW842166X
|
666260-75-9
|
98%
|
|
GW842166X is a potent and highly selective agonist of cannabinoid receptor CB2 receptor with EC50 of 63 nM, shows no significant activity at CB1 receptor. Phase ...
|
T19705 |
JTE-907
|
282089-49-0
|
98%
|
|
JTE-907 is a CB2 receptor inverse agonist with high selectivity and oral activity.JTE-907 exhibits anti-inflammatory activity in vivo.
|
T67896 |
CB2R/FAAH modulator-1
|
928892-60-8
|
98%
|
|
CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the productio...
|
TN2268 |
Tetrahydromagnolol
|
20601-85-8
|
98%
|
|
Tetrahydromagnolol can activate cannabinoid (CB) receptors.
|
T3530 |
Otenabant
|
686344-29-6
|
98%
|
|
Otenabant has been investigated for the treatment of Obesity.
|
T8511 |
TM38837
|
1253641-65-4
|
98%
|
|
TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.
|
T24771 |
SCH-336
|
447459-51-0
|
98%
|
|
SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100...
|
T9114 |
β-Caryophyllene
|
87-44-5
|
98%
|
|
β-Caryophyllene acts as an CB2 receptor agonist.
|
TN5131 |
Tetrahydrocannabivarin
|
31262-37-0
|
98%
|
|
Tetrahydrocannabivarin is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, th...
|
T14302 |
Olorinab
|
1268881-20-4
|
98%
|
|
Olorinab (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.
|
T1915 |
AM251
|
183232-66-8
|
98%
|
|
AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 ...
|
T3S0738 |
Yangonin
|
500-62-9
|
98%
|
|
1. Yangonin is a novel CB receptor ligand, it exhibits affinity for the human recombinant CB receptor. 2. Yangonin could be a valuable candidate for the interv...
|
T7375 |
A-836339
|
959746-77-1
|
98%
|
|
A-836339 acts as a potent cannabinoid receptor full agonist which has a higher affinity for the peripheral CB2 receptor (Ki = 0.64 nM) over the central CB1 recep...
|
T3699 |
Bay 59-3074
|
406205-74-1
|
98%
|
|
Bay 59-3074 is a CB1/CB2 receptor partial agonist (Ki: 48.3/45.5 nM). In rat models of chronic neuropathic and inflammatory pain, it displays anti-hyperalgesic a...
|
T2635 |
Org 27569
|
868273-06-7
|
98%
|
|
Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity and e...
|
T1519L |
Rimonabant
|
168273-06-1
|
98%
|
|
Rimonabant is an inverse agonist for the cannabinoid receptor CB1. It is an anorectic anti-obesity drug produced and marketed by Sanofi-Aventis. Its main avenue ...
|