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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T13410 | ZLDI-8 | Apoptosis , Phosphatase , Gamma-secretase , Immunology/Inflammation related | |
ZLDI-8 is an inhibitor of Notch activating/cleaving enzyme ADAM-17 and inhibits the cleavage of Notch protein. | |||
TP2108 | TAPI 2 | ||
ADAM-17 (TACE) and MMP inhibitor (Ki = 120 nM at ADAM-17). Sensitizes cancer stem cells to the lethal effects of 5-FU in vitro. Blocks shedding of TNF-α from cell membranes. | |||
TP2107 | TAPI 0 | ||
ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-03308 | ADAM17 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
ADAM17 is a member of the ADAM protein family of disintegrins and metalloproteases. ADAM17 is ubiquitously expressed in the human colon, with increased activity in the colonic mucosa of patients with ulcerative coliti... | |||
TMPK-00918 | ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His) | Human | HEK293 Cells |
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essent... | |||
TMPY-00423 | FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) | Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17. |