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T38449 |
Guanosine 5'-triphosphate-5'-adenosine
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GpppA,Guanosine 5'-triphosphate-5'-adenosine |
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Guanosine 5'-triphosphate-5'-adenosine, known as a 5′ cap analog, serves as a fluorescent substrate analog. |
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T40721 |
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine
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N7-Methyl-guanosine-5'-triphosphate-5'-adenosine,m7GpppA |
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N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog employed in the process of in vitro RNA transcription. |
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T83827 |
Adenosine-5'-O-(3-thiotriphosphate) sodium
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ATPγS,Adenosine 5'-(γ-thio)-triphosphate |
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Adenosine-5'-O-(3-thiotriphosphate) (ATPγS), an agonist of the purinergic P2Y11 receptor, prompts inositol phosphate accumulation in CHO-K1 cells harboring the human or canine P2Y11 receptor with EC50 values of 1.2 and 1... |
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T74135 |
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
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N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1]. |
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T69111 |
2',3'-Dialdehyde ATP
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2',3'-Dialdehyde ATP is a derivative of, and the oxidized form of, ATP. It has been found to be a specific, irreversible inhibitor of component A3 of the methylreductase system which plays a role in processing amino acid... |
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T2615 |
Flavopiridol hydrochloride
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Alvocidib Hydrochloride,NSC 649890,MDL 107826A,HL 275,FLAVOPIRIDOL HCL,NSC 649890 HCl |
HIV Protease
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CDK
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Autophagy
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Flavopiridol hydrochloride (MDL 107826A) is a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of ... |
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T71473 |
AWD 122-60
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AWD 122-60 is a cardiotonic bipyridine that inhibits adenosine triphosphate-sensitive potassium channels of mouse skeletal muscle. |
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T0373L1 |
Erlotinib mesylate
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CP-358774,CP-358,774,OSI-774,CP358774,OSI 774 |
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Erlotinib is an epidermal growth factor receptor inhibitor. Erlotinib binds in a reversible fashion to the adenosine triphosphate (ATP) binding site of the receptor. |
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T32085 |
HM30181AK
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HM-30181AK,HM 30181AK |
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HM30181AK is an inhibitor of the adenosine triphosphate (ATP) binding cassette (ABC) transporter P-glycoprotein (P-gp) with adjuvant activity. |
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T69648 |
Inupadenant HCl
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Inupadenant, also known as EOS-850, is a highly selective small molecule antagonist of the adenosine A2a receptor, in the adenosine triphosphate adenosine pathway, a key driver of immunosuppression in the tumor microenv... |
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T40663 |
9,10-Dichlorostearic acid
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9,10-Dichlorostearic acid is a chlorinated stearic acid that possesses antimutagenic properties. In vitro studies show that this compound induces membrane damage in mammalian tumor cells by causing leakage of adenosine t... |
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T37106 |
2'-Deoxyadenosine-5'-triphosphate (sodium salt hydrate)
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2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibi... |
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T39856 |
Purine riboside triphosphate
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PTP,Purine riboside triphosphate |
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Purine riboside triphosphate, a derivative of purine riboside, exhibits structural similarity to adenosine. This naturally occurring base analog possesses inhibitory effects on carcinogenic growth, particularly in cancer... |
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T40696 |
2'-NH2-ATP
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2'-NH2-ATP,2'-Amino-2'-deoxyadenosine-5'-triphosphate |
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2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate) is an adenosine derivative compound that acts as a weak competitive inhibitor of ATP with a K i value of 2.3 mM. It finds utility in nucleic acid labeling. |
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T40455 |
8-NH2-ATP
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8-Aminoadenosine-5'-O-triphosphate,8-NH2-ATP |
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8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado. It has been documented that 8-NH2-Ado exhibits potent properties, as evidenced by its ability to induce apoptosis-associate... |
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T75326 |
ATP ditromethamine
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ATP ditromethamine (Adenosine 5'-triphosphate ditromethamine), a vital in vivo energy storage and metabolic constituent, fuels metabolic pumps and acts as a cellular coenzyme. It also plays a crucial role as an endogenou... |
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T75325 |
ATP dimagnesium
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Adenosine 5'-triphosphate (ATP) dimagnesium, a pivotal molecule in energy storage and metabolism, fuels metabolic pumps and acts as a coenzyme within cells. Additionally, it plays a significant role as an endogenous sign... |
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T74772 |
Antifungal agent 47
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Antifungal agent 47 (compound 3b) exhibits the most potent and broad-spectrum fungicidal properties, including significant inhibition of respiration and adenosine 5′-triphosphate synthesis, showcasing its potential as an... |
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T60303 |
Collagen-IN-1
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Collagen-IN-1 (compound 3) is an ortho-carbonyl hydroquinone derivative exhibiting selective inhibition of collagen. It non-competitively inhibits agonist-induced platelet aggregation, with an IC50 value of 1.77 μM. Coll... |
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T74033 |
6-Me-ATP
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6-Me-ATP (N6-Methyl-ATP), a N6-modified adenosine triphosphate (ATP) derivative, exhibits strong binding affinity for glycogen synthase kinase 3 (GSK3) and acts as the phosphate group donor in GSK3β-catalyzed phosphoryla... |
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T68267 |
RO5068760
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RO5068760 , a substituted hydantoin, is a potent, highly selective, non-adenosine triphosphate (ATP)-competitive MEK1/2 inhibitors. RO5068760 shows significant efficacy in a broad spectrum of tumors with aberrant mitogen... |
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T35573 |
Adenosine 5’-methylenediphosphate (hydrate)
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Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or ... |
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T31200 |
Dansylmethionine
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Dansyl methionine,Dansyl-met |
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Dansylmethionine is a common cosubstrate involved in methyl group transfers, transsulfuration, and aminopropylation. Although these anabolic reactions occur throughout the body, most SAM-e is produced and consumed in the... |
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T72120 |
Guanosine 5'-diphosphate sodium
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GDP sodium |
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Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel and serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin i... |
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T68581 |
AP23464
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AP23464 is a potent adenosine 5'-triphosphate (ATP)-based inhibitor of Src and Abl kinases, displays antiproliferative activity against a human CML cell line and Bcr-Abl-transduced Ba/F3 cells (IC(50) = 14 nM. AP23464 ab... |
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T37733 |
AMP-PNP tetralithium
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Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.
Brady (1985) A novel brain ATPase with properties expect... |
