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Search Results for " EBOV "

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阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T80640	EBOV-IN-1		Influenza Virus
	EBOV-IN-1 is an adamantane dipeptide piperazine inhibitor against Ebola virus (EBOV) that inhibits EBOV infection and suppresses pseudotypic EBOV infection.		Influenza Virus
T68749	EBOV-IN-C31
	EBOV-IN-C31 is a novel PP1-targeting Ebola Virus (EBOV) inhibitor with improved pharmacological properties.
T62709	EBOV-GP-IN-1
	EBOV-GP-IN-1 (Compound 28) is a potent inhibitor of Ebola entry, acting on the Ebola virus envelope glycoprotein (EBOV-GP) (IC50: 0.05 μM).
T11281L	FGI-106 tetrahydrochloride		Virus Protease , HCV Protease , Influenza Virus , HIV Protease

T15641	K777	APC-3316	P450 , Cysteine Protease , CCR
	K777 is a potent, orally active and irreversible inhibitor of cysteine protease. K777 is a potent CYP3A4 inhibitor (IC50= 60 nM). K777 is also a selective CCR4 antagonist featuring the potent chemotaxis inhibition. K777 ...		P450 , Cysteine Protease , CCR
T8903	Retro-2	Retro 2,2-{[(5-methyl-2-thienyl)methylene]amino}	Others , Virus Protease , Parasite , Autophagy
	Retro-2 (2-{[(5-methyl-2-thienyl)methylene]amino}) is a plant toxin ricin inhibitor, itprotects HeLa cells against Ricin, Stx1 and Stx2, selectively blocks retrograde toxin trafficking at the early endosome-TGN (trans-Go...		Others , Virus Protease , Parasite , Autophagy
T16914	SP187	UV4,MON-DNJ	Others , Virus Protease , Influenza Virus
	SP187 (MON-DNJ) is a host-targeted iminosugar. It has anti-filovirus infection activity.SP187 is used for therapeutic use against influenza and dengue viruses.		Others , Virus Protease , Influenza Virus
T72019	ZINC32540717
	ZINC32540717 is a potent ebolavirus (EBOV) inhibitor.
T71999	ZINC09410451
	ZINC09410451 is a potent ebolavirus (EBOV) inhibitor.
T73571	CP19
	CP19, a histamine receptor antagonist, serves as an entry inhibitor for Ebolavirus (EBOV) and Marburgvirus (MARV), exhibiting inhibitory concentrations (IC50s) of 3.4 μM for EBOV and 29.5 μM for MARV, respectively. It de...
T39335	Anti-virus agent 1	Anti-virus agent 1,Remdesivir isopropyl ester analog
	Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734, exhibits potent antiviral efficacy. It is primarily utilized in the study of coronavirus and Ebola virus (EBOV).
T77150	Cosfroviximab
	Cosfroviximab (c13C6-FR1) is a chimeric monoclonal antibody derived from mouse and human sources, designed to target the Ebola virus glycoprotein (EBOV-GP) [1].
T76848	Atoltivimab
	Atoltivimab (REGN3470), also known as maftivimab/odesivimab (Inmazeb), represents the first monoclonal antibody approved by the Food and Drug Administration (FDA) to combat Zaire ebolavirus (EBOV) infection [1].
TP2184	Matrix protein (3-15) [Zaire ebolavirus]		Others
	matrix protein (3-15) [Zaire ebolavirus] is a peptide of the structural proteins linking the viral envelope with the zaire ebolavirus core. Ebola virus (EBOV) is a member of the family Filoviridae in the order Mononegavi...		Others
T73652	Eritoran
	Eritoran, a Toll-like receptor 4 (TLR4) antagonist, effectively protects mice from lethal infections caused by viruses such as the Ebola virus (EBOV) and Marburg virus (MARV). By decreasing granulocytosis levels, Eritora...
T0139	Toremifene	GTx 006,Z-Toremifene	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Toremifene (GTx 006) is a selective estrogen-receptor modulator (SERM).		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T11281	FGI-106		Others
	FGI-106 is a potent, broad-spectrum inhibitor demonstrating activity against various viruses, including Ebola, Rift Valley Fever, and Dengue Fever, exhibiting EC50 values of 100 nM, 800 nM, and 400-900 nM, respectively. ...		Others

Compounds

EBOV-IN-1

T80640

Synonym:

Target: Influenza Virus

FGI-106 tetrahydrochloride

T11281L

Synonym:

Target: Virus Protease, HCV Protease, Influenza Virus, HIV Protease

K777

T15641

Synonym: APC-3316

Target: P450, Cysteine Protease, CCR

Retro-2

T8903

Synonym: Retro 2,2-{[(5-methyl-2-thienyl)methylene]amino}

Target: Others, Virus Protease, Parasite, Autophagy

SP187

T16914

Synonym: UV4,MON-DNJ

Target: Others, Virus Protease, Influenza Virus

Synonym: Anti-virus agent 1,Remdesivir isopropyl ester analog

matrix protein (3-15) [Zaire ebolavirus]

Synonym: GTx 006,Z-Toremifene

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

カタログ番号	製品名	別名	ターゲット
T3S1852	Cephaeline hydrochloride		Others , Virus Protease , Influenza Virus
	Cephaeline hydrochloride, a phenolic alkaloid found in Indian Ipecac, effectively inhibits the infection of viruses ZIKV and EBOV.		Others , Virus Protease , Influenza Virus

天然物製品

Cephaeline hydrochloride

T3S1852

Synonym:

Target: Others, Virus Protease, Influenza Virus

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00065	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.4 kDa and the accession number...
TMPY-00307	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) EBOV-G/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the a...
TMPY-00071	Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain Ebola virus H.sapiens-wt/SLE/2014/ManoRiver-G3686.1) Glycoprotein/EBOV-G Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 k...
TMPY-00038	Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Protein (His)	EBOV	Baculovirus Insect Cells
	Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.3 kDa and the accession number is Q05320.
TMPY-00234	Ebola virus EBOV (subtype Sudan, strain Gulu) GP-RBD/Glycoprotein Protein (hFc)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Sudan, strain Gulu) GP-RBD/Glycoprotein Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 59 kDa and the accession number is A0A0E3KN50.
TMPY-00308	Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His)	EBOV	E. coli
	Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.8 kDa and the accession number is A0A2U8KL52.
TMPY-00238	Ebola virus EBOV (subtype Sudan, strain Gulu) GP1/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Sudan, strain Gulu) GP1/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.5 kDa and the accession number is A0A0E3KN50.
TMPY-00235	Ebola virus EBOV (subtype Sudan, strain Gulu) GP/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Sudan, strain Gulu) GP/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.9 kDa and the accession number is A0A0E3KN50.
TMPY-00067	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP24 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) VP24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.5 kDa and the accession number is B8XCN4.
TMPY-00243	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP-RBD/Glycoprotein Protein (hFc)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP-RBD/Glycoprotein Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 43.1 kDa and the accession number is B8XCN...
TMPY-00236	Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q05320.
TMPY-00232	Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) GP-RBD/Glycoprotein Protein is expressed in HEK293 mammalian cells. The predicted molecular weight is 31.5 kDa and the accession number is Q05320.
TMPY-00247	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP1/Glycoprotein Protein (His)	EBOV	Baculovirus Insect Cells
	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) GP1/Glycoprotein Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 53.5 kDa and the accession number is B8XCN...
TMPY-04159	Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP Protein (aa 1-637, His)	EBOV	Baculovirus Insect Cells
	Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP Protein (aa 1-637, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 67.9 kDa and the accession number is A0A0E3KN...
TMPY-00219	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP24 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP24 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.5 kDa and the accession numbe...
TMPY-00216	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.5 kDa and the accession number is B0LPL6.
TMPY-04526	Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His)	EBOV	E. coli
	Ebola virus EBOV (Sudan ebolavirus, strain Gulu) Nucleoprotein/NP Protein (aa 361-738, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 44.1 kDa and the accession number is A...
TMPY-00043	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His)	EBOV	Baculovirus Insect Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 69.3 kDa and the acces...
TMPY-00281	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP)	EBOV	E. coli
	Ebola virus EBOV (subtype Sudan, strain Gulu) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight is 79.1 kDa and the accession numb...
TMPY-00255	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP2/Glycoprotein Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 43.4 kDa and the accessio...
TMPY-00041	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His)	EBOV	Baculovirus Insect Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP1 Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 52.3 kDa and the acce...
TMPY-00178	Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain Mayinga 1976) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 57.6 kDa and the acc...
TMPY-00312	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Nucleoprotein/NP Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.6 kDa and the acc...
TMPY-00177	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Bundibugyo, strain Uganda 2007) Glycoprotein/GP-RBD (Receptor Binding Domain) Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 57.6 kDa and the...
TMPY-00240	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) GP1/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.3 kDa and the access...
TMPY-00245	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Makona-Kissidougou-C15) GP/Glycoprotein Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.3 kDa and the ...
TMPY-00199	Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP1 (mucin domain deleted) Protein (aa 1-320, His)	EBOV	Baculovirus Insect Cells
	Ebola virus EBOV (Subtype Sudan, strain Gulu) Glycoprotein/GP1 (mucin domain deleted) Protein (aa 1-320, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 33.8 kDa and the acce...
TMPY-00102	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the acc...
TMPY-00098	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (Fc)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP-RBD Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 57.6 kDa and the acces...
TMPY-00284	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) VP40/Matrix protein VP40 Protein (His & MBP) is expressed in E. coli expression system with His and MBP tag. The predicted molecular weight i...
TMPY-00064	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His)	EBOV	E. coli
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Matrix protein VP40 Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.1 kDa and the ...
TMPY-00292	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His)	EBOV	HEK293 Cells
	Ebola virus EBOV (subtype Zaire, strain H.sapiens-wt/GIN/2014/Kissidougou-C15) Glycoprotein/GP (Virion spike glycoprotein) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight...
TMPH-03405	Reston ebolavirus (REBOV) (strain Philippines-96) Nucleoprotein/NP Protein (His & SUMO)	REBOV	E. coli
	Reston ebolavirus (REBOV) (strain Philippines-96) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.3 kDa and the accession number...
TMPH-01269	SMURF2 Protein, Human, Recombinant (His)	Human	E. coli
	E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with SMAD7 to trigger SMA...