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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T6697 | TCID | UCH-L3 Inhibitor | DUB |
TCID (UCH-L3 Inhibitor)(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1. | |||
T22126 | Org 25543 hydrochloride | GlyT | |
Org 25543 hydrochloride is a potent and selective glycine transporter type 2 (GlyT2) inhibitor (IC50 = 16 nM for hGlyT2). Displays no activity at GlyT1 or 56 other common biological targets (≥ 100 μM), in a glycine uptak... | |||
T9833 | Opiranserin hydrochloride | P2X Receptor , GlyT , 5-HT Receptor | |
Opiranserin (VVZ-149) hydrochloride is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. It shows antagonistic activity on rP2X3 (IC50... | |||
T37735 | Stearoyl-L-carnitine chloride | C18 Carnitine,Stearoylcarnitine chloride | |
Stearoyl-L-carnitine chloride (Acylcarnitine C18:0) is a long-chain acylcarnitine found in the cerebellum that inhibits GlyT2 and is an important component in the study of lipid metabolism. | |||
T14198 | ALX-1393 | GlyT | |
ALX-1393 is a selective GlyT2 inhibitor that effectively reduces neuronal action potential activity in a concentration-dependent manner and inhibits the activity of spontaneous networks by inducing glycinergic tetanic cu... | |||
T35087 | VVZ-149 | VVZ 149 | |
VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity. | |||
T74739 | Oleoyl-D-lysine | ||
Oleoyl-D-lysine, a lipid-based selective Glycine Transporter-2 (GlyT2) inhibitor, effectively reverses neuropathic pain and exhibits an antidrowsiness effect in mice with chronic neuropathic pain. It is considered safe a... | |||
T70643 | GT-0198 HCl | ||
GT-0198 is a novel glycine transporter 2 inhibitor showed activity in a mouse model of neuropathic pain. GT-0198 inhibited the function of glycine transporter 2 (GlyT2) in human GlyT2-expressing HEK293 cells and did not ... | |||
T16399 | Opiranserin | P2X Receptor , GlyT , 5-HT Receptor | |
Opiranserin is a development as an injectable agent for the treatment of postoperative pain. Opiranserin is a non-opioid and non-NSAID analgesic candidate and is a dual antagonist of glycine transporter type 2 (GlyT2) an... | |||
T83872 | Oleoyl-L-carnitine chloride | L-Carnitine oleoyl ester,L-Octadecanoylcarnitine,C18:1 Carnitine,CAR 18:1 | |
Oleoyl-L-carnitine, a long-chain acylcarnitine, acts as a selective inhibitor of glycine transporter 2 (GlyT2; IC50 = 340 nM) while demonstrating significantly lesser affinity for GlyT1 (IC50 = >10,000 nM). Elevated plas... | |||
T23040 | N-Arachidonylglycine | Others | |
N-Arachidonylglycine is a biologically active lipid molecule that belongs to arachidonic acid derivatives. It has a wide range of biological activities including anti-inflammatory, anti-cancer, anti-diabetic and antioxid... |