|
T11950 |
MAT2A inhibitor 2
|
|
Others
,
Methionine Adenosyltransferase (MAT)
|
|
MAT2A inhibitor 2 is an inhibitor of methionine adenosyltransferase 2A (MAT2A). |
|
T9262 |
MAT2A inhibitor 4
|
|
Others
,
Methionine Adenosyltransferase (MAT)
|
|
MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancer research. |
|
T73140 |
MAT2A-IN-9
|
|
Methionine Adenosyltransferase (MAT)
|
|
MAT2A-IN-9, a 2-oxoquinazoline derivative, is a potent MAT2A (methionine adenylyltransferase 2A) inhibitor.MAT2A-IN-9 has antitumor activity for the treatment of lymphomas and solid tumors. |
|
T16013 |
MAT2A inhibitor 1
|
|
Others
|
|
MAT2A inhibitor 1 is an inhibitor of methionine adenosyltransferase 2A (MATA2) (IC50 < l00 nM). |
|
T63975 |
MAT2A-IN-1
|
|
|
|
MAT2A-IN-1 is a potent inhibitor of MAT2A and is capable of proliferative activity in MTAP-deficient cancer cells. MAT2A is expressed at unusually high levels in several tumour types, including gastric, colon, liver and ... |
|
T60903 |
MAT2A-IN-4
|
|
|
|
MAT2A-IN-4 can be used for the cancer research that is an inhibitor of methionine adenosyltransferase 2A (MAT2A)[1]. |
|
T62984 |
MAT2A-IN-2
|
|
|
|
MAT2A-IN-2 is a potent inhibitor of MAT2A. MAT2A-IN-2 has potential for cancer disease research. |
|
T60668 |
MAT2A inhibitor 3
|
|
|
|
MAT2A inhibitor 3 can be used in the cancer research. MAT2A inhibitor 3 is a inhibitor of methionine adenosyltransferase 2A (MAT2A) with an IC 50 of <200 nM [1]. |
|
T79349 |
MAT2A-IN-11
|
|
Methionine Adenosyltransferase (MAT)
|
|
MAT2A Allosteric Inhibitor 1, also known as Compound 5, is a selective inhibitor of methionine adenosyltransferase (MAT) demonstrating potent activity with an IC50 value of 6.8 nM [1]. |
|
T83973 |
MAT2A-IN-8
|
|
|
|
MAT2A-IN-8 is an inhibitor of MAT2A. |
|
T62100 |
MAT2A-IN-6
|
|
|
|
MAT2A-IN-6 is a potent inhibitor of MAT2A. MAT2A-IN-6 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-6 has shown potential research value in cancer diseases. |
|
T63603 |
MAT2A-IN-3
|
|
|
|
MAT2A-IN-3 is a potent inhibitor of MAT2A. MAT2A-IN-3 inhibits the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-3 has shown research potential for cancer diseases. |
|
T61243 |
MAT2A-IN-5
|
|
|
|
MAT2A-IN-5, a potent inhibitor of MAT2A, effectively targets the abnormally elevated expression of MAT2A found in various tumor types such as gastric, colon, liver, and pancreatic cancers. By reducing the proliferative a... |
|
T61672 |
MAT2A-IN-7
|
|
|
|
MAT2A-IN-7, a potent inhibitor of the enzyme MAT2A, demonstrates efficacy in targeting the abnormally elevated expression of MAT2A observed in gastric, colon, liver, and pancreatic cancers. Furthermore, MAT2A-IN-7 effect... |
|
T78946 |
MAT2A-IN-10
|
|
Methionine Adenosyltransferase (MAT)
|
|
MAT2A-IN-10 (Compound 28), an orally active inhibitor of MAT2A, exhibits an IC50 of 26 nM and is utilized in cancer research [1]. |
|
T79350 |
MAT2A-IN-12
|
|
Methionine Adenosyltransferase (MAT)
|
|
MAT2A Allosteric Inhibitor 2 is a potent, selective inhibitor exhibiting an IC50 of 5 nM and demonstrates nanomolar efficacy (IC50 = 5 μM) in proliferation assays utilizing the MTAP -/- cell line [1]. |
|
T11284 |
FIDAS-3
|
|
Others
,
Wnt/beta-catenin
,
Methionine Adenosyltransferase (MAT)
|
|
FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for ... |
|
T11285 |
FIDAS-5
|
|
Others
|
|
FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities. |
|
T14141 |
AGI-24512
|
|
Others
,
Methionine Adenosyltransferase (MAT)
|
|
AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in vitro. |
|
T9050 |
AG-270
|
|
Others
,
Methionine Adenosyltransferase (MAT)
|
|
AG-270 is an allosteric and orally active inhibitor of MAT2A. |
|
T5191 |
PF-9366
|
|
Others
,
Methionine Adenosyltransferase (MAT)
|
|
PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor (IC50: 420 nM; Kd: 170 nM). |
|
T9729 |
AGI-43192
|
|
Others
|
|
AGI-43192 is a potent methionine adenosine transferase 2A (MAT2A) inhibitor that penetrates the blood-brain barrier. AGI-43192 inhibits S-adenosine methionine (SAM) production metabolic enzyme and methionine adenosine tr... |
|
T9730 |
AGI-41998
|
|
|
|
AGI-41998 is a potent inhibitor of methionine adenosyltransferase 2A (MAT2A) that penetrates the blood-brain barrier.AGI-41998 inhibits s-adenosylmethionine (SAM) metabolizing enzymes and methionine adenosyltransferase 2... |
