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T7700 |
Lersivirine
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Lersivirine(UK 453061),UK-453061 |
HIV Protease
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Reverse Transcriptase
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Lersivirine (UK-453061)(UK 453061) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) under development for HIV infection therapy. |
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T2330 |
Rilpivirine
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TMC278,R278474,DB08864 |
HIV Protease
,
Reverse Transcriptase
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Rilpivirine (R278474) is a diarylpyrimidine derivative and reverse transcriptase inhibitor with antiviral activity against HIV-1 that is used in the treatment of HIV infections. |
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T7212 |
Delavirdine mesylate
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U 90152 (mesylate),BHAP-U 90152 (mesylate),Delavirdine (mesylate) |
HIV Protease
,
Reverse Transcriptase
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Delavirdine mesylate (BHAP-U 90152 (mesylate)) is a non-nucleoside reverse transcriptase inhibitor (NNRTI). |
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T78948 |
NNRTIs-IN-1
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NNRTIs-IN-1 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) with notable anti-resistance efficacy, effectively inhibiting both the wild-type HIV-1 and five mutant strains at EC50 values within the nano... |
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T78737 |
NNRTIs-IN-3
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HIV Protease
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NNRTIs-IN-3 (compound 8) is an HIV-1 non-nucleoside reverse transcriptase inhibitor, displaying potent efficacy with an EC50 value of 0.01 µM [1]. |
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T31860 |
Fosdevirine
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GSK-2248761A,IDX 899,GSK 2248761A,GSK 2248761,GSK-2248761,IDX-12899,GSK2248761,FDV,GSK2248761A |
HIV Protease
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Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy. |
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T9223 |
RO-0335
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Reverse Transcriptase
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RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical is... |
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T31860L |
(Iso)-Fosdevirine
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(Iso)-Fosdevirine（Iso-1018450-26-4）,(Iso)-GSK2248761 |
HIV Protease
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(Iso)-Fosdevirine ( (Iso)-GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological disorders such as late-onset epilepsy. |
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T29037 |
UC-781
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NSC 675186,UC781,UC 781 |
Antiviral
,
HIV Protease
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UC-781 (NSC-675186) is a potent and selective inhibitor of human immunodeficiency virus HIV-1 non-nucleoside reverse transcriptase (NNRTI) I with a C50 value of 5 nM.UC-781 exhibits both antiviral activity and drug resis... |
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T27625 |
IQP-0528
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SJ-3991,SJ3991,IQP0528 |
Antiviral
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HIV Protease
,
Reverse Transcriptase
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IQP-0528 is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) that has potential for the treatment of HIV infection by blocking viral entry and shows antiviral activity as a microbicidal gel. . IQP-0528 sho... |
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T31085 |
CP-94707
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UNII-YGC6408B5O |
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CP-94707 is a new inhibitor of nonnucleoside reverse transcriptase (NNRTI). |
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T72582 |
HIV-1 inhibitor-48
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HIV-1 inhibitor-48 is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity . |
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T26442 |
A 75925
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A-75925,A75925 |
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A 75925, a nonnucleoside reverse transcriptase inhibitors (NNRTI), works to inhibit HIV-1 replication. |
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T70794 |
Nevirapine dimer
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Nevirapine dimer is a non-nucleoside reverse transcriptase inhibitor (NNRTI). |
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T71517 |
Nevirapine quinone methide
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Nevirapine quinone methide is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS. |
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T70156 |
K-5a2
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K-5a2 is a novel human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor (NNRTI). |
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T11247 |
Etravirine D4
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R-165335 D4,TMC-125 D4 |
Others
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Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Etravirine D4 is the deuterium labeled Etravirine. |
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T69796 |
Nevirapine hemihydrate
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Nevirapine hemihydrate is a non-nucleoside reverse transcriptase inhibitor (NNRTI) studied for potential treatment of HIV-1 infection and AIDS. |
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T27442 |
GSK 224876
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GSK-224876,GSK224876 |
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GSK 224876 is a novel next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI). It has activity against efavirenz-resistant strains in the treatment of treatment-naive HIV-1-infected subjects. |
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T7212L |
Delavirdine
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Rescriptor,DLV,U 90152,BHAP-U 90152 |
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Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Delavirdine is part of Highly Active Antiretroviral Therapy (HAART), which can be used to treat human immunodeficiency virus (HIV) type 1. |
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T72566 |
HIV-1 inhibitor-50
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HIV-1 inhibitor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (IC50 = 50 nM). HIV-1 inhibitor-50 shows significant antiviral activity, with EC50s of 2.22-53.3nM a... |
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T79837 |
Bavtavirine
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Bavtavirine, a potent non-nucleoside reverse transcriptase inhibitor (NNRTI), forms an integral component of the highly active antiretroviral therapy (HAART) regimen for HIV disease research [1]. |
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T63677 |
HIV-1 inhibitor-13
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HIV-1 inhibitor-13 is an orally active HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) with an IC50 value of 0.14 μM against HIV-1 RT. HIV-1 inhibitor-13 is active against HIV-1 resistant strains (EC50: 2.85... |
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T62452 |
HIV-1 inhibitor-40
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HIV-1 inhibitor-40 (Compound 4ab) is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) (EC50: 1.9 nM) with no significant acute toxicity in vivo. Orexin receptor antagonist is a highly sensitive inhibitor o... |
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T63363 |
HIV-1 inhibitor-19
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HIV-1 inhibitor-19 is a potent inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRTI) that acts on L100I, K103N and V106A/F227L mutant strains with EC50s of 7.3 nM, 9.2 nM and 21.0 nM, respectively. |
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T26581 |
AIC-292
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AIC-292 is a potent reverse transcriptase inhibitor with well tolerated in different cell lines. In addition, activity of AIC292 could be demonstrated against a broad panel of wild-type HIV-1 group. AIC292 also retained ... |
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T78749 |
HIV-1 inhibitor-57
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HIV-1 Inhibitor-57 (Compound 12g) is an antiviral agent that potently inhibits both wild-type and five common NNRTI-resistant strains of HIV-1, exhibiting EC50 values between 0.024 and 0.0010 μM. It achieves this efficac... |
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T62526 |
HIV-1 inhibitor-8
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HIV-1 inhibitor-8 is a potent, orally active, low toxicity HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI). HIV-1 inhibitor-8 is capable of acting on WT HIV-1 reverse transcriptase (IC50: 0.081 μM). HIV-1 in... |
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T61311 |
HIV-1 inhibitor-30
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HIV-1 inhibitor-30 (compound 10i) is a potent inhibitor of HIV-1, specifically targeting the RT DNA polymerase enzyme. It exhibits strong antiretroviral activity, with an EC 50 value of 40 nM and an IC 50 value of 80 nM.... |
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T78925 |
HIV-1 inhibitor-58
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HIV-1 Inhibitor-58 (Compound 10c) is a non-nucleoside reverse transcriptase inhibitor with broad-spectrum antiviral properties, effective against both wild-type strain IIIB and NNRTI-resistant strains like K103N and E138... |
