PROTAC Linker-10 | TargetMol

カタログ番号	製品名	別名	ターゲット
T7701	Boc-NH-PEG3	PROTAC Linker 10	Others , PROTAC Linker
	Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative containing a hydroxyl group and Boc-protected amino group, and is a PROTAC linker.		Others , PROTAC Linker
T14413	Azido-PEG10-alcohol		Others , PROTAC Linker
	Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].		Others , PROTAC Linker
T17694	Br-C10-methyl ester		Others , PROTAC Linker
	Br-C10-methyl ester, a PROTAC linker characterized by its alkyl/ether composition, plays a crucial role in the synthesis of a series of PROTACs (MS432). This compound incorporates a dual-ligand system connected via a lin...		Others , PROTAC Linker
T17881	(S,R,S)-AHPC-C10-NH2	VH032-C10-NH2	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC-C10-NH2 (VH032-C10-NH2) is a synthesized E3 ligase ligand-linker conjugate, comprising the (S,R,S)-AHPC-based VHL ligand and a linker, designed for BET-targeted PROTAC applications.		Others , Ligand for E3 Ligase
T18661	(S,R,S)-AHPC-C10-NH2 dihydrochloride	VH032-C10-NH2 dihydrochloride,VH032-linker 10,VH032 amide-alkylC10-amine	Others , Ligand for E3 Ligase
	(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate incorporating the (S,R,S)-AHPC based VHL ligand and a linker[1].		Others , Ligand for E3 Ligase
T18680	SD-36		Others , PROTACs
	SD-36, a potent and efficacious PROTAC STAT3 degrader (Kd=~50 nM), exhibits high specificity for STAT3 over other STAT members. It effectively targets both wild-type and mutated STAT3 proteins in cells, inhibiting their ...		Others , PROTACs
T13999	(10-BRomodecyl)phosphonic acid		Others
	(10-BRomodecyl)phosphonic acid is an alkyl chain-derived PROTAC linker suitable for PROTAC synthesis [1].		Others
T17901	CIAP1 Ligand-Linker Conjugates 10	E3 ligase Ligand-Linker Conjugates 47	Others
	cIAP1 Ligand-Linker Conjugates 10 comprise of an IAP ligand and a PROTAC linker, which facilitates the design of SNIPERs. These conjugates incorporate an IAP ligand that interacts with the E3 ubiquitin ligase, and a PROT...		Others
T15120	Diethyl 10-bromodecylphosphonate		Others
	Diethyl 10-bromodecylphosphonate is an alkyl-based PROTAC linker utilized for the synthesis of PROTACs[1].		Others
T18515	Palbociclib-propargyl	PROTAC CDK6 ligand 1	Others
	Palbociclib-propargyl, a PROTAC ligand targeting the protein CDK6, connects to the CRBN ligand through a PEG linker to form PROTAC CP-10. CP-10 exhibits a potent DC50 value of 2.1 nM against CDK6[1].		Others
T14000	[10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid		Others
	The compound [10-(diethoxy-phosphoryl)-decyl]-phosphonic acid is a suitable alkyl chain-based PROTAC linker for the synthesis of PROTACs [1].		Others
T16583	Propargyl-PEG1-acid		Others
	Propargyl-PEG1-acid, a PEG-based PROTAC linker, enables the synthesis of BTK-CRBN PROTACs, specifically Ibrutinib-based PROTAC 4 and PROTAC 5. At a concentration of 10 μM, PROTAC 5 facilitates the degradation of BTK and ...		Others
T18682	SJFδ		Others
	SJFδ is a 10-atom linker PROTAC. SJFδ degrades p38δ with a DC50 of 46.17 nM, but does not degrade p38α, p38β, or p38γ[1].		Others
T15834	M-PEG10-alcohol	Decaethylene glycol monomethyl ether	Others
	m-PEG10-alcohol, also known as Decaethylene glycol monomethyl ether, is a non-cleavable 10 unit PEG ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, m-PEG10-alcohol serves as a PE...		Others
T17904	Pomalidomide-PEG1-C2-N3	E3 ligase Ligand-Linker Conjugates 50,Cereblon Ligand-Linker Conjugates 13	Others
	Pomalidomide-PEG1-C2-N3 is a compound that has been synthesized as a conjugate of an E3 ligase ligand-linker. This compound incorporates the cereblon ligand based on Pomalidomide and a 1-unit PEG linker, which are common...		Others
T18601	Desmethyl-QCA276	PROTAC BRD4-binding moiety 4	Others
	Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, and with a Ki of 2.3 nM[1].		Others
T71919	Boc-10-Aminodecanoic acid
	Boc-10-Aminodecanoic acid can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Boc-10-Aminodecanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino g...
T41146	ND1-YL2	ND1-YL2
	ND1-YL2 is a peptide-based PROTAC®Degrader of steroid receptor co-activator 1 (SRC-1; also known as nuclear receptor coactivator 1, NCOA1). ND1-YL2 is composed of a stapled peptide that binds SRC-1 (YL2) joined by a link...
T83856	AP-1
	AP-1, a miniaturized proteolysis-targeting chimera (PROTAC) incorporating an anaplastic lymphoma kinase (ALK) ligand connected to (±)-thalidomide via an ultrashort linker, effectively degrades ALK fusion proteins such as...

Compounds

Boc-NH-PEG3

T7701

Synonym: PROTAC Linker 10

Target: Others, PROTAC Linker

Azido-PEG10-alcohol

T14413

Synonym:

Target: Others, PROTAC Linker

Br-C10-methyl ester

T17694

Synonym:

Target: Others, PROTAC Linker

(S,R,S)-AHPC-C10-NH2

T17881

Synonym: VH032-C10-NH2

Target: Others, Ligand for E3 Ligase

(S,R,S)-AHPC-C10-NH2 dihydrochloride

T18661

Synonym: VH032-C10-NH2 dihydrochloride,VH032-linker 10,VH032 amide-alkylC10-amine

Target: Others, Ligand for E3 Ligase

SD-36

T18680

Synonym:

Target: Others, PROTACs

(10-BRomodecyl)phosphonic acid

T13999

Synonym:

Target: Others

cIAP1 Ligand-Linker Conjugates 10

T17901

Synonym: E3 ligase Ligand-Linker Conjugates 47

Target: Others

Diethyl 10-bromodecylphosphonate

T15120

Synonym:

Target: Others

Palbociclib-propargyl

T18515

Synonym: PROTAC CDK6 ligand 1

Target: Others

[10-(Diethoxy-phosphoryl)-decyl]-phosphonic acid

Synonym: Decaethylene glycol monomethyl ether

Target: Others

Pomalidomide-PEG1-C2-N3

T17904

Synonym: E3 ligase Ligand-Linker Conjugates 50,Cereblon Ligand-Linker Conjugates 13

Target: Others

Desmethyl-QCA276

T18601

Synonym: PROTAC BRD4-binding moiety 4

Target: Others

Boc-10-Aminodecanoic acid

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02300	BIN1 Protein, Human, Recombinant (His)	Human	E. coli
	Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicat...
TMPY-01751	DR3/TNFRSF25 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	DR3/TNFRSF25 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.
TMPY-00961	ADAM15 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10.
TMPY-05760	DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated	Human	HEK293 Cells
	DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10.