|
T30778 |
CCG-257081
|
MRTF/SRF-IN-1,CCG257081,CCG 257081 |
Rho
,
Ras
|
|
CCG-257081 (MRTF/SRF-IN-1) is an inhibitor of cardiac myosin-related transcription factor and serum response factor (MRTF/SRF) that acts by inhibiting the Rho/MRTF/SRF pathway.CCG-257081 has shown efficacy in preventing ... |
|
T80568 |
Casdozokitug
|
SRF-388 |
|
|
Casdozokitug (SRF-388) is an IgG1κ monoclonal antibody that specifically targets interleukin-27 (IL-27) [1]. |
|
T22062 |
CCG-100602
|
|
Rho
,
Ras
|
|
CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells (IC50 :9.8 μM). |
|
T4306 |
CCG-203971
|
CCG203971 |
Rho
,
Ras
|
|
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50: 6.4 μM), with 87% inhibition of SRE activation achieved at 100 μM. This compound also inhibits PC-3 cell migration (IC50: 4.2 μM),... |
|
T2014 |
CCG-1423
|
CCG1423 |
LRRK2
,
Rho
,
Ras
|
|
CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription. |
|
T26967 |
CCG-232601
|
CCG 232601,CCG232601 |
|
|
CCG-232601 is a inhibitor of the Rho/MRTF/SRF transcriptional pathway. |
|
T82766 |
CCG-232964
|
|
ROCK
|
|
CCG-232964 is an orally active Rho/MRTF/SRF inhibitor that suppresses LPA-induced CTGF gene expression [1]. |
|
T68431 |
CCG-58150
|
|
|
|
CCG-58150 is a potentiInhibitor of Rho/Myocardin-Related Transcription Factor (MRTF)/Serum Response Factor (SRF)-Mediated Gene Transcription
as Potential Antifibrotic Agents for Scleroderma. |
|
T23221 |
(R)-CCG-1423
|
|
Others
|
|
(R)-CCG-1423 is a stereoisomer of CCG-1423. CCG-1423 is a Rho inhibitor involved in blocking signaling through myocardin-related transcription factor A (MRTF-A) and serum response factor (SRF). |
