8
7
4
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T20256 | Sorbitol, L- | L-Glucitol | Others |
Sorbitol, L- is a sugar alcohol. It can be obtained by the reduction of glucose, which changes the aldehyde group to a hydroxyl group. It is converted to fructose by sorbitol-6-phosphate 2-dehydrogenase. Sorbitol is an i... | |||
T32193 | Iron sorbitex | Jectofer,Yectofer,Iron Sorbitol,HSDB 1967,Astra 1572 | Others |
Iron Sorbitex is used for the treatment of Iron Sorbitex deficiency anemia in patients with chronic kidney disease. Iron Sorbitex can be used as an Iron Sorbitex replacement product used for the treatment of Iron Sorbite... | |||
T2013 | Ponalrestat | Reductase | |
Ponalrestat is an aldose reductase inhibitor. | |||
T0503 | Meglumine | Meglumin,Methylglucamin,Methylglucamine | Others |
Meglumine (Meglumin), a derivative of sorbitol, is used in conjunction with iodinated organic compounds as contrast medium. | |||
T9527 | Span-85 | Sorbitan trioleate | Others |
Span-85 (Sorbitan trioleate) is a synthetic non-ionic emulsifier, which is prepared by partial esterification of sorbitol or sorbitan with food grade palmitic acid. It has low viscosity and the smallest HLB value, so it ... | |||
T31070 | CP-642931 | CP 642931,UNII-4Q45INJ6TQ | Others |
Cp-642931 is an effective and specific sorbitol dehydrogenase inhibitor (SDI). | |||
T20767 | Sorbitan monostearate | Span 55,Emsorb 2505,Sorbon S 60,Liposorb S-20,Sorgen 50 | Others |
Sorbitan monostearate is an ester of stearic acid and sorbitan (a sorbitol derivative), it is also sometimes referred to as a synthetic wax. | |||
T78702 | PTP1B/AKR1B1-IN-1 | Phosphatase | |
PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s of 0.06 μM for PTP1B and 4.3 μM for AKR1B1. Additionally, it... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T0332 | D-Sorbitol | Glucitol,Sorbitol,D-Glucitol | Others , Endogenous Metabolite |
D-Sorbitol (Sorbitol) is a polyhydric alcohol with about half the sweetness of sucrose. D-Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be use... | |||
T0585 | Maltitol | 4-O-α-glucopyranosyl-D-sorbitol,Maltisorb | Others |
Maltitol (4-O-α-glucopyranosyl-D-sorbitol) is a sugar alcohol (polyol) used as a sugar substitute. | |||
TQ0195 | 1,5-Anhydrosorbitol | Others , Endogenous Metabolite | |
1,5-Anhydrosorbitol is a validated marker of short-term glycemic control. This substance is derived mainly from food. | |||
T7964 | Isomalt | Palatinitol,Palatinit | Others , Dehydrogenase |
Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside | |||
T5S1988 | Isorhamnetin-3-O-glucoside | Isorhamnetin-3-O-beta-D-Glucoside | Others |
Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) inhibits the activity of alpha-glucosidase from rat intestine; it exhibits a potent rat lens aldose reductase (RLAR) inhibition in vitro, its IC(50) being 1.... | |||
T0414 | D-Mannitol | Mannite,Mannitol,Osmitrol | Apoptosis , Dehydrogenase , Endogenous Metabolite |
D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to t... | |||
TN2201 | Semilicoisoflavone B | Others | |
Semilicoisoflavone B can inhibit sorbitol formation of rat lens incubated with a high concentration of glucose, indicates that it may be effective for preventing osmotic stress in hyperglycemia. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00524 | SORD Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expresse... | |||
TMPY-02438 | AKR1B1 Protein, Human, Recombinant (His) | Human | E. coli |
Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest... | |||
TMPY-04460 | OXSR1 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environme... | |||
TMPY-02461 | AKR1A1 Protein, Human, Recombinant (His) | Human | E. coli |
Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehy... |