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Search Results for " Sorbitol "

ターゲット

8

阻害剤

7

天然化合物

4

リコンビナントタンパク質

カタログ番号 製品名 別名 ターゲット
T20256 Sorbitol, L- L-Glucitol Others
Sorbitol, L- is a sugar alcohol. It can be obtained by the reduction of glucose, which changes the aldehyde group to a hydroxyl group. It is converted to fructose by sorbitol-6-phosphate 2-dehydrogenase. Sorbitol is an i...
T32193 Iron sorbitex Jectofer,Yectofer,Iron Sorbitol,HSDB 1967,Astra 1572 Others
Iron Sorbitex is used for the treatment of Iron Sorbitex deficiency anemia in patients with chronic kidney disease. Iron Sorbitex can be used as an Iron Sorbitex replacement product used for the treatment of Iron Sorbite...
T2013 Ponalrestat Reductase
Ponalrestat is an aldose reductase inhibitor.
T0503 Meglumine Meglumin,Methylglucamin,Methylglucamine Others
Meglumine (Meglumin), a derivative of sorbitol, is used in conjunction with iodinated organic compounds as contrast medium.
T9527 Span-85 Sorbitan trioleate Others
Span-85 (Sorbitan trioleate) is a synthetic non-ionic emulsifier, which is prepared by partial esterification of sorbitol or sorbitan with food grade palmitic acid. It has low viscosity and the smallest HLB value, so it ...
T31070 CP-642931 CP 642931,UNII-4Q45INJ6TQ Others
Cp-642931 is an effective and specific sorbitol dehydrogenase inhibitor (SDI).
T20767 Sorbitan monostearate Span 55,Emsorb 2505,Sorbon S 60,Liposorb S-20,Sorgen 50 Others
Sorbitan monostearate is an ester of stearic acid and sorbitan (a sorbitol derivative), it is also sometimes referred to as a synthetic wax.
T78702 PTP1B/AKR1B1-IN-1 Phosphatase
PTP1B/AKR1B1-IN-1 is a dual inhibitor targeting protein tyrosine phosphatase 1B (PTP1B) and aldose reductase (AKR1B1), exhibiting inhibitory potency with IC50s of 0.06 μM for PTP1B and 4.3 μM for AKR1B1. Additionally, it...
カタログ番号 製品名 別名 ターゲット
T0332 D-Sorbitol Glucitol,Sorbitol,D-Glucitol Others , Endogenous Metabolite
D-Sorbitol (Sorbitol) is a polyhydric alcohol with about half the sweetness of sucrose. D-Sorbitol occurs naturally and is also produced synthetically from glucose. It was formerly used as a diuretic and may still be use...
T0585 Maltitol 4-O-α-glucopyranosyl-D-sorbitol,Maltisorb Others
Maltitol (4-O-α-glucopyranosyl-D-sorbitol) is a sugar alcohol (polyol) used as a sugar substitute.
TQ0195 1,5-Anhydrosorbitol Others , Endogenous Metabolite
1,5-Anhydrosorbitol is a validated marker of short-term glycemic control. This substance is derived mainly from food.
T7964 Isomalt Palatinitol,Palatinit Others , Dehydrogenase
Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside
T5S1988 Isorhamnetin-3-O-glucoside Isorhamnetin-3-O-beta-D-Glucoside Others
Isorhamnetin-3-O-glucoside (Isorhamnetin-3-O-beta-D-Glucoside) inhibits the activity of alpha-glucosidase from rat intestine; it exhibits a potent rat lens aldose reductase (RLAR) inhibition in vitro, its IC(50) being 1....
T0414 D-Mannitol Mannite,Mannitol,Osmitrol Apoptosis , Dehydrogenase , Endogenous Metabolite
D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to t...
TN2201 Semilicoisoflavone B Others
Semilicoisoflavone B can inhibit sorbitol formation of rat lens incubated with a high concentration of glucose, indicates that it may be effective for preventing osmotic stress in hyperglycemia.

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00524 SORD Protein, Human, Recombinant (His) Human HEK293 Cells
Sorbitol dehydrogenase, also known as L-iditol 2-dehydrogenase and SORD, is a member of the zinc-containing alcohol dehydrogenase family. SORD exsits in a homotetramer and binds one zinc ion per subunit. SORD is expresse...
TMPY-02438 AKR1B1 Protein, Human, Recombinant (His) Human E. coli
Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest...
TMPY-04460 OXSR1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environme...
TMPY-02461 AKR1A1 Protein, Human, Recombinant (His) Human E. coli
Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehy...