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T36730 |
Vitamin K1 2,3-epoxide
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Vitamin K1 epoxide,Phylloquinone oxide,Vitamin K1 2,3-epoxide |
Others
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Vitamin K1 2,3-epoxide (Phylloquinone oxide) is reduced to vitamin k and is involved in the vitamin k cycle. |
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T7636 |
Phenprocoumon
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Others
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Phenprocoumon is an antagonist of vitamin K(IC50:1 μM). |
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T5963 |
Menadione bisulfite sodium
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Sodium menadione bisulfite,Menadione sodium bisulfite,Vitamin K3 sodium bisulfite |
Others
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Menadione bisulfite sodium (Vitamin K3 sodium bisulfite) is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement. |
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T0360 |
Chlorindione
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chlophenadione,Indaliton,G-25766 |
Others
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Chlorindione (chlophenadione) is a vitamin K antagonist, a potent anticoagulant compound. |
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T17025 |
Tecarfarin
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ATI-5000,ATI-5923 |
Others
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Tecarfarin (ATI-5923) is an orally active and potent vitamin K epoxide reductase (VKOR) antagonist and cannabinoid-1 receptor inverse agonist with antithrombotic activity that attenuates abdominal pain and increases inte... |
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T4980 |
Betrixaban maleate
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Factor Xa
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Betrixaban maleate is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa. |
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T0815L |
Warfarin sodium
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Others
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An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, an... |
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T4341 |
Betrixaban
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PRT054021 |
Factor Xa
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Betrixaban (PRT054021) is a non-vitamin K oral anticoagulant whose action is driven by the competitive and reversible inhibition of the factor Xa [1]. It was selected among all lead compounds due to its low hERG channel ... |
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T10867 |
Coumetarol
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Ph 137,Dicumoxane |
Others
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Coumetarol is an antagonist of vitamin K. |
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T75435 |
Cis-Vitamin K1
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Others
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Cis-Vitamin K1 is an endogenous metabolite of Vitamin K [1] . |
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T17024 |
Tecarfarin sodium
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ATI-5923 sodium |
Others
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Tecarfarin sodium is a novel orally active non-competitive vitamin K epoxide reductase antagonist. Tecarfarin sodium has the antithrombotic activity. |
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T71543 |
Difethialone
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Others
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Difethialone is an anticoagulant rodenticide and a vitamin K antagonist. |
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T19708 |
(S)-Warfarin
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Others
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(S)-Warfarin is a more effective enantiomer of Warfarin. It is used as a vitamin K antagonist, with anticoagulant. |
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T36725 |
6-hydroxy Warfarin
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Others
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6-Hydroxywarfarin is a metabolite of (+)-warfarin and a weak vitamin K antagonist. |
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T62662 |
Tioclomarol
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Others
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Tioclomarol is a coumarin anticoagulant and a vitamin K antagonist. |
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TP1628 |
Activated Protein C (390-404), human
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Activated Protein C (390-404), human, a peptide derived from the vitamin K-dependent serine protease, effectively suppresses the anticoagulant activity of APC[1]. |
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T81205 |
SARS-CoV-2-IN-66
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SARS-CoV
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SARS-CoV-2-IN-66 (1), a derivative of vitamin K, functions as an inhibitor of SARS-CoV-2, exhibiting an effective concentration (EC50) of 70.8 μM in VeroE6/TMPRSS2 cells [1]. |
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T37950 |
2-(Isopentylamino)naphthalene-1,4-dione
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Others
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2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, r... |
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T81204 |
SARS-CoV-2-IN-67
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SARS-CoV
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SARS-CoV-2-IN-67 (Compound 16), a derivative of vitamin K, exhibits anti-SARS-CoV-2 properties, with an effective concentration (EC50) of 64.8 μM in VeroE6/TMPRSS2 cells, and inhibits SARS-CoV-2 RdRp activity [1]. |
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T22676 |
Prothrombin (474-477) [Mus musculus]
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Others
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Prothrombin (coagulation factor II) is produced in the liver and is post-translationally modified in a vitamin K-dependent reaction that converts ten glutamic acids on prothrombin into gamma-carboxyglutamic acid. Prothro... |
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T85174 |
3-keto Sphinganine (d12:0) hydrochloride
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3-keto Sphinganine (d12:0),3-keto Dihydrosphingosine (d12:0) |
Others
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3-Keto Sphinganine (d12:0) is a short-chain analog of 3-keto sphinganine (d18:0), which typically possesses a C18 chain length. The latter is a lyso-sphingolipid synthesized through the condensation of L-serine and palmi... |
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T36203 |
Menaquinone 9
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MK-9,Vitamin K2(45),Menaquinone 9 |
Others
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Menaquinone 9 (MK-9) is a vitamin K2 analog that has been found in various bacteria, including E. coli. MK-9 is UV-sensitive and binds to soluble nitrate reductase, a component of the bacterial electron transport chain. ... |
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T21693 |
PPM-18
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Others
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PPM-18 (NSC 73233) is a potent anti-inflammatory agent which inhibits nitric oxide synthase expression. PPM-18 is a potent inhibitor of iNOS expression by blocking the binding of NF-κB to promoter [1]. PPM-18 is an analo... |
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T36564 |
(S)-Acenocoumarol
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Others
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Acenocoumarol is a short-lived oral anti-coagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. It has higher intrinsic anticoagulant potency than warfarin and phenprocoumon, when evaluated... |
