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阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T9618	HeE1-2Tyr		SARS-CoV
	HeE1-2Tyr, a pyridobenzothiazole compound, is a flavivirus RNA dependent RNA polymerases (RdRp) inhibitor. It significantly inhibits West Nile, Dengue and SARS-CoV-2 RdRps (IC50 of 27.6 µM) activity in vitro.		SARS-CoV
T72041	Flaviviruses-IN-2		Virus Protease
	Flaviviruses-IN-2 is a potent flaviviruses inhibitor. Flaviviruses-IN-2 reduces West Nile virus (WNV) protease activity and inhibits WNV by 56%.		Virus Protease
T67777	Flaviviruses-IN-3	WAY-324593	Virus Protease
	Flaviviruses-IN-3 (compound 87) is a potent inhibitor of flaviviruse. Flaviviruses-IN-3 could reduce the WNV (West Nile virus) protease activity, with a inhibition of 54%.		Virus Protease
TNU0060	3’-O-Methyladenosine		Antiviral , Adenosine deaminase
	3’-O-Methyladenosine is an antiviral compound with inhibitory activity against West Nile Virus and can be used for the treatment of viral infections.3’-O-Methyladenosine inhibits adenosine deaminase type VII with a Ki va...		Antiviral , Adenosine deaminase
T4027	KIN1148		Influenza Virus
	KIN1148 is a novel small-molecule adjuvant that acts through the RIG-I pathway and IRF-3 transcription factor to stimulate inN/Ate immunity and protection following viral infection. The adjuvant will be developed for an ...		Influenza Virus
TNU0007	3'-Deoxy-3'-fluoroadenosine		Nucleoside Antimetabolite/Analog
	3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne encephalitis virus (TBEV), Zika virus and West Nile virus (WNV...		Nucleoside Antimetabolite/Analog
T33381	Micordilin
	Micordilin is isolated from West Indian medicinal plant Mikania cordifolia.
T70855	Favipiravir sodium
	Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as o...
T38861	Tat-beclin 1
	Tat-beclin 1, a peptide derived from the autophagy protein beclin 1, is a powerful inducer of autophagy. It interacts with GAPR-1 (GLIPR2), a negative regulator of autophagy. Tat-beclin 1 effectively reduces the buildup ...
T81309	RCB16007
	RCB16007 is a Yellow Fever Virus (YFV) inhibitor that also demonstrates inhibitory action against the West Nile virus with an effective concentration (EC50) of 7.9 μM and a cytotoxic concentration (CC50) of 17 μM [1].
T76058	Tat-beclin 1 TFA
	Tat-beclin 1 TFA, a peptide originating from a segment of the autophagy protein beclin 1, effectively initiates autophagy and engages with the autophagy negative regulator, GAPR-1 (GLIPR2). It notably reduces the buildup...

Compounds

Target: Virus Protease

Flaviviruses-IN-3

T67777

Synonym: WAY-324593

Target: Virus Protease

3’-O-Methyladenosine

TNU0060

Synonym:

Target: Antiviral, Adenosine deaminase

KIN1148

T4027

Synonym:

Target: Influenza Virus

3'-Deoxy-3'-fluoroadenosine

TNU0007

Synonym:

Target: Nucleoside Antimetabolite/Analog

カタログ番号	製品名	別名	ターゲット
T2718	Palmatine chloride		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
	Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
T5S0802	Palmatine	Berbericinine,Burasaine	Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
	1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T3S0693	Blinin		Others
	Blinin, isolated from the whole plant of Conyza blinii, is used in folk medicine in the south-west of China.		Others
T25789	Melianone	NSC 302037,NSC-302037,NSC302037
	Melianone exhibits antiviral activity (EC50s: 3-11μM) against three important human pathogens, belonging to the Flaviviridae family, West Nile virus, Dengue virus, and Yellow Fever virus.
T72508	Palmatine hydroxide
	Palmatine hydroxide is an orally active, irreversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1), demonstrating IC50 values of 3 μM for HEK 293-hIDO-1 and 157μM for rhIDO-1. Additionally, it uncompetitively inhib...

天然物製品

Palmatine chloride

T2718

Synonym:

Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase

Palmatine

T5S0802

Synonym: Berbericinine,Burasaine

Target: Indoleamine 2,3-Dioxygenase (IDO), AChR, AChE, Aurora Kinase

Synonym: NSC 302037,NSC-302037,NSC302037

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04735	West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein (His)	WNV	HEK293 Cells
	West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.1 kDa and the accession number is YP_001527881.1.
TMPY-04299	West Nile Virus (WNV) (lineage 1, strain NY99) E/Envelope Protein (His)	WNV	P. pastoris (Yeast)
	West Nile Virus (WNV) (lineage 1, strain NY99) E/Envelope Protein (His) is expressed in yeast with His tag. The predicted molecular weight is 12.9 kDa and the accession number is ABA62343.1.
TMPY-04787	West Nile Virus (WNV) (lineage 2, strain Nea Santa-Greece-2010) E/Envelope Protein (His)	WNV	P. pastoris (Yeast)
	West Nile Virus (WNV) (lineage 2, strain Nea Santa-Greece-2010) E/Envelope Protein (His) is expressed in yeast with His tag. The predicted molecular weight is 12.9 kDa and the accession number is AED99787.1.
TMPH-03664	Vaccinia virus (strain Western Reserve) OPG161 Protein (His)	VACV	P. pastoris (Yeast)
	Coordinates the incorporation of A36 into wrapped enveloped virion (EV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral particles. V...
TMPH-03668	Vaccinia virus (strain Western Reserve) OPG190 Protein (E. coli, His)	VACV	E. coli
	Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV). V...
TMPH-03672	Vaccinia virus (strain Western Reserve) K3 Protein (His & SUMO)	VACV	E. coli
	Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2/PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2/PKR kinase and prevents protein synthesis shutoff. Vaccinia virus (strain W...
TMPY-03250	Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin/HA Protein (His)	H15N2	Baculovirus Insect Cells
	Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59 kDa and the accession numbe...
TMPH-03659	Vaccinia virus (strain Western Reserve) OPG094 Protein (His)	VACV	P. pastoris (Yeast)
	Envelope protein part of the entry-fusion complex responsible for the virus membrane fusion with host cell membrane during virus entry. Also plays a role in cell-cell fusion (syncytium formation). Vaccinia virus (strain ...
TMPY-04189	Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin/HA1 Protein (His)	H15N2	HEK293 Cells
	Influenza A H15N2 (A/Australian shelduck/Western Australia/1756/1983) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.6 kDa and the accession numb...
TMPH-03661	Vaccinia virus (strain Western Reserve) OPG154 Protein (His & Myc)	VACV	E. coli
	Structural protein involved in the envelopment of mature virion (MV) to form the wrapped virion (WV). The wrapping consists of the addition of Golgi membranes to the mature virion. Participates in mature virion (MV) move...
TMPH-03675	Vaccinia virus (strain Western Reserve) L1 Protein (E. coli, His)	VACV	E. coli
	Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion ...
TMPH-03669	Vaccinia virus (strain Western Reserve) OPG190 Protein (His)	VACV	P. pastoris (Yeast)
	Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV). V...
TMPH-03657	Vaccinia virus (strain Western Reserve) OPG057 Protein (His & Myc)	VACV	E. coli
	Major envelope protein that plays a role in the biogenesis of the viral double membrane and in egress of virus from the host cell. Produces the wrapped form of virus that is required for cell-to-cell spread. Acts as a li...
TMPH-03676	Vaccinia virus (strain Western Reserve) L1 Protein (His)	VACV	P. pastoris (Yeast)
	Envelope protein which probably plays a role in virus entry into the host cell. Is probably involved in the virus attachment to the host cell surface and associates with the entry/fusion complex (EFC). Needed for fusion ...
TMPH-03654	Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)	VACV	E. coli
	Catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal...
TMPH-03671	Vaccinia virus (strain Western Reserve) K3 Protein (His)	VACV	P. pastoris (Yeast)
	Viral mimic of eIF-2-alpha that acts as a pseudosubstrate for EIF2AK2/PKR kinase. Inhibits therefore eIF-2-alpha phosphorylation by host EIF2AK2/PKR kinase and prevents protein synthesis shutoff. Vaccinia virus (strain W...
TMPY-02841	Fragilis/IFITM3 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interf...