|
T0082 |
Domperidone
|
R33812 |
Dopamine Receptor
|
|
Domperidone (R33812)(Motilium) is a dopamine blocker and an antidopaminergic reagent. It blocks the action of. It has strong affinities for the D2 and D3 dopamine receptors, which are found in the chemoreceptor trigger z... |
|
T6905 |
Netupitant
|
Ro 67-31898/000,CID 6451149 |
Neurokinin receptor
|
|
Netupitant (CID 6451149) is a specific neurokinin 1 (NK1) receptor antagonist (Ki: 0.95 nM). |
|
T0370 |
Pheniramine maleate
|
Daneral,Inhiston,Trimetose |
5-HT Receptor
,
Histamine Receptor
|
|
Pheniramine maleate (Trimetose), an alkylamine derivative with antihistaminic and vasodilatory properties, binds to histamine H1 receptors, thereby inhibiting phospholipase A2 and production of the endothelium-derived re... |
|
T11121 |
Duoperone
|
|
Others
|
|
Duoperone is a neuroleptic agent. Duoperone shows antiemetic activity in animal models. |
|
T10819 |
Cipropride S enantiomer
|
|
Others
|
|
Cipropride S enantiomer is the S enantiomer of cipropride which is an antiemetic drug. |
|
T28187 |
Nonabine
|
|
|
|
Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy. |
|
T6615 |
Ondansetron
|
GR-C507/75,GR 38032,GR 38032F,SN 307 |
5-HT Receptor
|
|
Ondansetron (GR 38032) is a serotonin 5-HT3 receptor antagonist used mainly as an antiemetic. |
|
T9881 |
Benzoquinamide hydrochloride
|
3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride |
Others
|
|
Benzoquinamide hydrochloride (3-carbamoyl-N,N-diethyl-1,3,4,6,7,11b-hexahydro-9,11-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate hydrochloride) is an antiemetic agent and increases intra-arterial pressure due to the incre... |
|
T28537 |
Ricasetron
|
Brl 46470,Brl46470,Brl-46470 |
5-HT Receptor
|
|
Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysis and antiemetic properties, and is used in the study of anxiety and anxiety disorders. |
|
T5009 |
Trimethobenzamide hydrochloride
|
Ro 2-9578,Tribenzagan Hydrochloride |
Dopamine Receptor
,
Influenza Virus
|
|
Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting. |
|
T1042 |
Granisetron hydrochloride
|
BRL 43694A,Granisetron HCl |
5-HT Receptor
|
|
Granisetron hydrochloride (Granisetron HCl) is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients. |
|
T19991 |
N-desmethylmirtazapine
|
N-Demethylmirtazapine,Normirtazapine,ORG3838,ORG 3838,J1.061.658A,ORG-3838 |
Others
|
|
N-desmethylmirtazapine (J1.061.658A) is a metabolite of mirtazapine. N-desmethylmirtazapine is also commonly used as an anxiolytic, hypnotic, antiemetic, and appetite stimulant. |
|
T8441 |
Lerisetron
|
|
5-HT Receptor
|
|
Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity. |
|
T13329 |
Vofopitant
|
GR 205171 |
Neurokinin receptor
|
|
|
|
T6398 |
Azaperone
|
R-1929,Fluoperidol,Stresnil,NSC 170976,Suicalm |
Others
,
Dopamine Receptor
|
|
Azaperone (Fluoperidol) is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine. |
|
T1069 |
Metoclopramide hydrochloride
|
Maxolon,Metoclopramide HCl |
Dopamine Receptor
,
5-HT Receptor
,
AChR
|
|
Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. |
|
T0862 |
Diphenidol hydrochloride
|
Diphenidol HCl,Difenidol hydrochloride |
Sodium Channel
,
AChR
|
|
Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug. |
|
T1175 |
Bromopride
|
Bromoprida,Valopride,Artomey |
Dopamine Receptor
|
|
Bromopride (Valopride) is a dopamine antagonist with prokinetic properties closely related to metoclopramide, and is widely used as an antiemetic. It is not available in the United States or the United Kingdom. |
|
T3282 |
Alimemazine hemitartrate
|
Alimemazine Tartrate,Methylpromazine Tartrate,Trimeprazine tartrate,Trimeprazine hemitartrate |
Others
|
|
Alimemazine hemitartrate (Trimeprazine hemitartrate) is aphenothiazine derivative that is used as an antipruritic. It also acts as a sedative, hypnotic, and antiemetic for prevention of motion sickness. |
|
T1173 |
Tropisetron hydrochloride
|
SDZ-ICS 930,Tropisetron HCl,ICS 205-930 |
5-HT Receptor
|
|
Tropisetron hydrochloride (Tropisetron HCl) is the hydrochloride salt form of tropisetron, a selective, competitive serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist, with antinauseant and antiemetic activ... |
|
T24184 |
Itasetron
|
DAU6215CL,UNII-00S0D0OEKR,U-98079A,U 98079A,DAU 6215CL |
5-HT Receptor
|
|
Itasetron (U 98079A) is a 5-hydroxytryptamine 3-receptor antagonist used to prevent age-related memory deficits in rats.Itasetron's antiemetic activity in animal models of cancer chemotherapy and radiation therapy may be... |
|
T0766 |
Promazine hydrochloride
|
Romtiazin hydrochloride,Sinophenin hydrochloride |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
AChR
|
|
Promazine hydrochloride (Romtiazin hydrochloride) is a phenothiazine with actions similar to CHLORPROMAZINE but with less antipsychotic activity. It is primarily used in short-term treatment of disturbed behavior and as ... |
|
T1090 |
Perphenazine
|
Perphenazin,Etaperazine,Trilafon |
CaMK
,
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
Histamine Receptor
|
|
Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties. |
|
T0776 |
Phenothiazine
|
ENT 38 |
Dopamine Receptor
,
Antibacterial
,
Antibiotic
,
Antifungal
|
|
Phenothiazine (ENT 38) is a class of agents exhibiting antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Phenothiazines antagonize the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ)... |
|
T21419 |
Diphenhydramine
|
Debendrin,PM 255,PM255,Dabylen,Syntedril,PM-255 |
Histamine Receptor
|
|
Diphenhydramine (Syntedril), a first-generation antihistamine possessing antiemetic, antitussive, anticholinergic, and sedative properties, is mainly used in the treatment of allergies. Diphenhydramine is also used in th... |
|
T1222 |
Trifluoperazine dihydrochloride
|
Trifluoperazine 2HCl,SKF5019,Urinox |
CaMK
,
Dopamine Receptor
,
Influenza Virus
,
Adrenergic Receptor
,
P-gp
,
Autophagy
|
|
Trifluoperazine dihydrochloride (SKF5019) is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic. |
|
T0903 |
Cinnarizine
|
Stugeron,Cinarizine,Dimitronal,Stutgin |
Calcium Channel
,
Histamine Receptor
|
|
Cinnarizine (Stugeron) is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS. |
|
T0053 |
Hydroxyzine Pamoate
|
Hydroxyzine embonate,Bobsule,Equipose |
Histamine Receptor
|
|
Hydroxyzine Pamoate (Bobsule) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does ca... |
|
T1790 |
Fosaprepitant dimeglumine
|
L785298,MK-0517,Fosaprepitant dimeglumine salt |
Neurokinin receptor
|
|
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion... |
|
T12343 |
Benzquinamide
|
BZQ,P2647,Benzoquinamide |
Adrenergic Receptor
|
|
Benzquinamide (P2647), an antiemetic agent with anticancer activity, inhibits p-glycoprotein-mediated drug efflux and potentiates the cytotoxicity of anticancer drugs in multidrug-resistant cells.The Ki values of Benzqui... |
|
T21428 |
Mianserin
|
Lantanon,Lumin,Norval,Lerivon,Depnon |
Histamine Receptor
|
|
Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family. Mianserin has antidepressant, antianxiety, antiemetic, hypotrophic, hypnotic and antihistam... |
|
T2200 |
Hydroxyzine dihydrochloride
|
Hydroxyzine 2HCl |
Histamine Receptor
|
|
Hydroxyzine dihydrochloride (Hydroxyzine 2HCl) is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIR... |
|
T67956 |
Litoxetine
|
|
5-HT Receptor
|
|
Litoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently r... |
|
T6426 |
Buclizine dihydrochloride
|
Longifene,Buclina,Buclizine HCl,UCB-4445 |
5-HT Receptor
,
AChR
,
Histamine Receptor
|
|
Buclizine dihydrochloride (Buclina) is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine dihydrochloride binds to and ... |
|
T4562 |
Ramosetron
|
|
5-HT Receptor
|
|
Ramosetron is a serotonin 5-HT3 receptor antagonist for the treatment of nausea and vomiting. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondanse... |
|
T3716 |
Rolapitant
|
SCH619734 |
Neurokinin receptor
|
|
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ... |
|
T4616 |
Metoclopramide
|
5-Chloro-2-methoxyprocainamide |
Dopamine Receptor
,
5-HT Receptor
|
|
Metoclopramide (5-Chloro-2-methoxyprocainamide) is a dopamine D2 antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is ... |
|
T25794 |
Methiomeprazine
|
RP-10584,Metiomeprazina,RP 10584,RP10584 |
|
|
Methiomeprazine is an antiemetic agent. |
|
T10963 |
Dazopride
|
AHR-5531 |
Others
|
|
Dazopride is an antiemetic agent. |
|
T7569L |
Clebopride
|
|
|
|
Clebopride is antidopaminergic. Clebopride also has an effect of antiemetic. |
|
T0302L |
Triflupromazine
|
Vesprin,Fluopromazine,Trifluopromazine,Adazine,Siquil |
|
|
Triflupromazine is a phenothiazine drug used as an antipsychotic and antiemetic. |
|
T21420 |
Diphenidol
|
SKF-478,SKF478,SKF 478,Difenidolo,Difenidol |
|
|
Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent. |
|
T71588 |
Batanopride HCl
|
|
|
|
Batanopride is a antiemetic 5-HT3 receptor antagonist. |
|
T26650 |
Arazasetron HCl
|
WR85915,WR-85915,Y-25130,Y25130,WR 85915 |
|
|
Arazasetron is an antiemetic which acts as a 5-HT3 receptor antagonist, pKi = 9.27. |
|
T25486 |
Haloperidide
|
R 3201,R-3201,R3201 |
|
|
Haloperidide is an antiemetic. |
|
T40854 |
Imiclopazine
|
|
|
|
Imiclopazine is a phenothiazine derivative with good sedative, analgesic, antiaggressive and antiemetic effects. |
|
T27819 |
Levonantradol hydrochloride
|
CP-50,556-1,CP 50,556-1,Levonantradol HCl |
|
|
Levonantradol hydrochloride is a new compound with antiemetic activity. |
|
T26806 |
Bietanautine
|
Etanautine,Nautamine |
|
|
Bietanautine is an antiemetic biochemical. |
|
T23965 |
DAT 582
|
DAT582,DAT-582 |
|
|
DAT 582 is a novel serotonin3 receptor antagonist. It is also an effective and long-lasting antiemetic agent |
|
T22340 |
Granisetron
|
Sustol,Granisetronum,Sancuso,Kevatril |
5-HT Receptor
|
|
Granisetron, a serotonin receptor (5HT-3 selective) antagonist, is used as an antinauseant and antiemetic for cancer chemotherapy. |
