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阻害剤 血管新生 アポトーシス オートファジー 細胞周期・チェックポイント クロマチン・エピジェネティック 細胞骨格シグナル DNA損傷・DNA修復 内分泌・ホルモン GPCR/Gタンパク質 免疫・炎症 JAK・STATシグナル MAPK
膜輸送体・イオンチャネル 代謝 微生物学・ウィルス学 神経科学 NF-Κb 酸化還元 PI3K/Akt/mTORシグナル プロテアーゼ・プロテアソーム 幹細胞 チロシンキナーゼ・アダプター ユビキチン PROTAC
化合物ライブラリー 生物活性化合物ライブラリー ゼネラルバイオウアクティヴライブラリー 承認/再開発 医薬品ライブラリー 疾患別 化合物ライブラリー 標的/経路別 化合物ライブラリー 特徴的な生物活性化合物ライブラリー 天然化合物ライブラリー HTS用天然物ライブラリー 分野別 天然化合物ライブラリー 天然物誘導体ライブラリー CADD用天然物ライブラリー ドラッグライク 化合物ライブラリー フラグメントライブラリー カスタム化合物ライブラリー
シグナル伝達経路 血管新生 アポトーシス オートファジー 細胞周期・チェックポイント クロマチン・エピジェネティック 細胞骨格シグナル
DNA損傷・DNA修復 内分泌・ホルモン GPCR/Gタンパク質 免疫・炎症 JAK・STATシグナル MAPK 膜輸送体・イオンチャネル
代謝 微生物学・ウィルス学 神経科学 NF-Κb 酸化還元 PI3K/Akt/mTORシグナル プロテアーゼ・プロテアソーム
幹細胞 チロシンキナーゼ・アダプター ユビキチン その他 PROTAC
生物活性化合物ライブラリー ゼネラルバイオウアクティヴライブラリー 承認/再開発 医薬品ライブラリー 疾患別 化合物ライブラリー 標的/経路別 化合物ライブラリー 特徴的な生物活性化合物ライブラリー
天然化合物ライブラリー HTS用天然物ライブラリー 分野別 天然化合物ライブラリー 天然物誘導体ライブラリー CADD用天然物ライブラリー
ドラッグライク 化合物ライブラリー ドラッグライクライブラリー
フラグメントライブラリー ゼネラルフラグメントライブラリー 特徴的なフラグメントライブラリー カスタム化合物ライブラリー
Cytokines and Growth Factors •   Cytokines •   Growth Factors Receptor Proteins •   Fc Receptors •   Cytokines and Growth Factor Receptors
CD Proteins •   T Cell CD Proteins •   B Cell CD Proteins Immune Checkpoint Proteins •   Co-inhibitory Immune Checkpoint Proteins •   Co-stimulatory Immune Checkpoint Proteins
CAR-T Therapy Target Proteins •   Hematologic Malignancies Target Proteins •   Solid Tumors Target Proteins Enzymes •   Oxidoreductases,EC 1 •   Transferases,EC 2
Viral Proteins •   Coronavirus (CoV) Proteins •   Influenza Proteins Fluorescent Proteins Others

検索結果

Search Results for " bloodstream "

ターゲット

Influenza Virus Parasite Aurora Kinase Autophagy

17

阻害剤

5

天然化合物

13

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T6532 Hesperadin Influenza Virus , Parasite , Aurora Kinase , Autophagy
Hesperadin(IC50=250 nM) effectively inhibits Aurora B. It potently reduces the activity of AMPK, MAPKAP-K1, MKK1, Lck, CHK1 and PHK, but it could not inhibit MKK1 activity in vivo.
T4582 Xanthanol NSC 4038 Others
Xanthanol(NSC 4038) is used to test the levels of urea in the bloodstream.
T4179 Probucol disuccinate LDL
Probucol is an anti-hyperlipidemic drug initially developed in the treatment of coronary artery disease by lowering the level of cholesterol in the bloodstream by increasing the rate of LDL catabolism.
TP2107L Histrelin acetate Histrelin acetate(76712-82-8 free base) GNRH Receptor
Histrelin acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It acts on particular cells of the pituitary gland called gonadotropes when present in the bloodstream. Histrelin sti...
T70673 NEU617
NEU617 is an inhibitor of the growth of protozoan parasites, against T. brucei bloodstream proliferation.
T25490 Hemorphin 4 Tyr-pro-trp-thr
Hemorphin 4 is an endogenous opioid peptide of the hemorphin family which has antinociceptive properties and is derived from the β-chain of hemoglobin in the bloodstream.
T38967 DSPE-PEG(2000)
MPEG-2000-DSPE sodium is a phospholipid PEG conjugate with hydrophilicity and hydrophobicity. It is utilized in liposome synthesis to enhance the hydrophilicity of liposomes, thereby prolonging their circulation in the b...
T31215 DB-766 DB766
DB-766 is a potential chemotherapeutic candidate for Chagas' disease treatment. DB-766 exhibits strong trypanocidal activity and excellent selectivity for bloodstream trypomastigotes and intracellular amastigotes (Y stra...
T76332 Biotinyl-Glucagon (1-29), human, bovine, porcine
Biotinyl-Glucagon (1-29), encompassing human, bovine, and porcine versions, is a biotinylated form of glucagon. This peptide hormone, synthesized by the pancreas's α-cells, elevates glucose and fatty acid levels in the b...
T79457 PEX5-PEX14 PPI-IN-1
PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor that disrupts the interaction between PEX5 and TbPEX14 with an inhibitory constant (Ki) of 53 μM. It effectively inhibits the b...
T14967 Cimlanod BMS-986231,CXL-1427 Others
Cimlanod is a second-generation Nitroxyl (HNO) donor for heart failure with positive lusitropic and inotropic as well as vasodilatory effects. Cimlanod delivers HNO via pH-dependent chemical breakdown when exposed to the...
T78977 Antitrypanosomal agent 12 Parasite
Antitrypanosomal agent 12, a C20-phenylthiourea, exhibits trypanocidal and cytotoxic activities, demonstrating antitrypanosomal activity with GI50 values of 0.22 μM. It induces faster cell swelling in bloodstream-form tr...
T77111 Omodenbamab
Omodenbamab, a humanized monoclonal antibody targeting Staphylococcal protein A (SpA), exhibits a dissociation constant (K D) of 0.0467 nM, effectively countering a crucial S. aureus evasion strategy by focusing on the c...
T73676 MIF-1 TFA
MIF-1 TFA (Melanostatin), an intrinsic brain peptide, serves as a powerful allosteric modulator of the dopamine receptor. It plays a crucial role in regulating melanin production and modifies the analgesic efficacy by in...
TP1155 Human growth hormone-releasing factor Growth Hormone Releasing Factor human
Human growth hormone-releasing factor stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.Growth hormone-releasing hormone is a hormone produced in the hypothal...
T38503 (2-pyridyldithio)-PEG1-hydrazine (2-pyridyldithio)-PEG1-hydrazine
(2-Pyridyldithio)-PEG1-hydrazine is a one-unit cleavable polyethylene glycol (PEG) linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This linker offers the advantage of controlled release...
T64553 GLP-1(7-37) TFA salt
The truncated glucagon-like peptides GLP-1(7-37) is naturally occurring peptide product of the preproglucagon gene that are synthesized primarily in the intestine and acts as incretin that are released from the intestine...
カタログ番号 製品名 別名 ターゲット
T0254 Probucol DH-581 Virus Protease , ABC , Lipid
Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.
TN1051 1-Caffeoylquinic acid NF-κB
1-Caffeoylquinic acid is an important intermediate in lignin biosynthesis. 1-Caffeoylquinic acid has anti-influenza, and antioxidant activities, it also slows the release of glucose into the bloodstream after a meal.
T4776 Glycerol Glycerin Endogenous Metabolite
Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol...
TN2515 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one Antifection
(4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one shows growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes, with the IC(50) value in the range of 1-3 microg/mL.
T83903 Polymyxin B2 sulfate
Polymyxin B2, a significant component of polymyxin B, is an antibiotic cationic lipopeptide initially derived from B. polymyxa. This compound effectively inhibits P. aeruginosa, A. baumannii, K. pneumoniae, and E. cloaca...

天然物製品

Probucol
T0254
Synonym: DH-581
Target: Virus Protease, ABC, Lipid
1-Caffeoylquinic acid
TN1051
Synonym:
Target: NF-κB
Glycerol
T4776
Synonym: Glycerin
Target: Endogenous Metabolite
1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one
TN2515
Synonym:
Target: Antifection
Polymyxin B2 sulfate
T83903
Synonym:
Target:

Recombinant Proteins

Species：
Mouse (6)
Human (5)
Rabbit (1)
Sheep (1)
Expression System：
HEK293 (9)
E. coli (3)
Yeast (1)
Tag：
His (8)
C-terminal FC-Myc-tagged (1)
N-terminal 6xHis-SUMO-tagged (1)
N-terminal 6xHis-tagged (1)
N-terminal GST-tagged (1)
Tag-Free (1)
カタログ番号 製品名 Species Expression System
TMPH-02947 Transthyretin Protein, Mouse, Recombinant Mouse E. coli
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPH-02946 Transthyretin Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPH-02242 Transthyretin Protein, Human, Recombinant (hFc & Myc) Human HEK293
Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
TMPY-03118 ORM2 Protein, Human, Recombinant (His) Human HEK293
ORM2 belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, ...
TMPY-02167 Complement Factor D/CFD Protein, Mouse, Recombinant (His,HEK293) Mouse HEK293
Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement ...
TMPY-01256 TBG Protein, Human, Recombinant (His) Human HEK293
Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein that belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically ...
TMPY-02183 Complement Factor D/CFD Protein, Human, Recombinant (His) Human HEK293
Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement ...
TMPY-01240 TBG Protein, Mouse, Recombinant (His) Mouse HEK293
Thyroxine-binding globulin, also known as T4-binding globulin, Serpin A7 and TBG, is a secreted protein that belongs to the serpin family. TBG is synthesized primarily in the liver as a 54 kDa protein.TBG is genomically ...
TMPY-01027 Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I...
TMPY-01233 LRPAP1 Protein, Human, Recombinant (His) Human HEK293
Receptor-associated protein (RAP) is a molecular chaperone for low-density lipoprotein receptor-related protein (LRP), which plays a key role in cholesterol metabolism. The lipoprotein receptor-related protein (LRP) is a...
TMPH-03208 IL-6 Protein, Rabbit, Recombinant (His) Rabbit Yeast
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...
TMPY-01732 LRPAP1 Protein, Mouse, Recombinant (His) Mouse HEK293
Receptor-associated protein (RAP) is a molecular chaperone for low-density lipoprotein receptor-related protein (LRP), which plays a key role in cholesterol metabolism. The lipoprotein receptor-related protein (LRP) is a...
TMPH-03500 IL-6 Protein, Sheep, Recombinant (GST) Sheep E. coli
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-sign...
カタログ番号 製品名
L9850 Orally Active Compound Library

2484 compounds
A unique collection of 2484 of orally active compounds for high-throughput screening and high-content screening.

ライブラリー

Orally Active Compound Library
L9850
Compounds: 2484
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