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T6023 |
Nutlin-3a
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(-)-Nutlin-3,Nutlin-3a chiral,(−)-Nutlin-3 |
Apoptosis
,
E1/E2/E3 Enzyme
,
Autophagy
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Nutlin-3a ((−)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein. |
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T40247 |
Ethofumesate
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Others
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Ethofumesate is a chiral herbicide. Ethofumesate acts by inhibiting mitosis and reducing photosynthesis and plant respiration. |
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T19891 |
Metolachlor
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Others
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Metolachlor is an organic compound. Metolachlor is also widely used as an herbicide. |
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T2275 |
YK-4-279
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Apoptosis
,
DNA/RNA Synthesis
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YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1. |
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T20058 |
Prothioconazole
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HSDB7893,HSDB-7893,Proline 480 SC Fungicide,JAU 6476,HSDB 7893 |
Antifungal
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Prothioconazole (Proline 480 SC Fungicide) is a chiral triazole fungicide in plant pathogen control. |
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T19758 |
D-alpha-Methylbenzyl isothiocyanate
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Others
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D-alpha-Methylbenzyl isothiocyanate is an antioxidant. It induces phase II enzyme activity and is also used as a chiral agent. |
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T20224 |
L-Dithiothreitol
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L-Dtt |
Others
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L-Dithiothreitol (L-Dtt) is a chiral bidentate dithiol with two stereogenic centers. It may be used in chiroptical response research. |
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T0763 |
Hexylene glycol
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2-Methyl-2,4-pentanediol,Diolane,MPD |
Others
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Hexylene glycol (Diolane), colorless liquid, is a chiral diol. It is an industrial compound produced from diacetone alcohol by hydrogenation. |
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T72050 |
4-N-Dodecyloxyphenol
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4-dodecoxyphenol,p-Dodecyloxyphenol |
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4-N-Dodecyloxyphenol (p-Dodecyloxyphenol) is a compound that can be used as an additive to ferroelectric or ferroelectric liquid crystals or to display the SmC phase and has no chiral groups. |
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T50096 |
Neramexane HCl
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1,3,3,5,5-pentamethylcyclohexan-1-amine HCl |
Others
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1,3,3,5,5-pentamethylcyclohexan-1-amine hydrochloride, also known as PAC, is a cyclic amine commonly used as a chiral auxiliary in asymmetric syntheses including the Diels-Alder reaction, hydroxyaldol reaction, and Micha... |
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T0028 |
Gamibetal
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3-Hydroxy-GABA,4-Amino-3-hydroxybutyric Acid |
HIV Protease
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Gamibetal (4-Amino-3-hydroxybutyric Acid) is used as a chiral reagent in the synthesis of antiepileptic and hypotensive drug GABOB and analogues. Also used in the preparation of HIV-1 inhibitors derived from Betulinic Ac... |
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T50100 |
3-hydroxy-3-phenylpentanamide
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Others
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3-hydroxy-3-phenylpentanamide is a chiral compound belonging to the class of beta-hydroxyamides. In neurology, it has been shown to have neuroprotective effects against ischemic brain injury and cerebral hemorrhage. In p... |
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T26150 |
RU 35929
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RU-35929,RU35929 |
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RU 35929 is a chiral antiamnesic agent. |
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T33603 |
Nb-enantride
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Nb-enantride is a novel chiral trialkylborohydride for the asymmetric reduction of ketones. |
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T37812 |
6-O-Sulfo-β-cyclodextrin (sodium salt)
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6-O-Sulfo-β-cyclodextrin is a sulfated cyclodextrin.1It has been used for the chiral separation of nadolol racemates by capillary electrophoresis.
1.Wang, F., Dowling, T., Bicker, G., et al.Electrophoretic chiral separat... |
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T26033 |
RAC 109
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RAC-109,RAC109 |
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RAC 109 is a chiral antiarrhythmic agent. |
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T20269 |
Dibutyl tartrate
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AI3 00396,AI3-00396,AI300396 |
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Dibutyl tartrate is an agent of chiral surfactant. |
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T19745 |
Furalaxyl
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A 5430,A5430,A-5430 |
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Furalaxyl is an fungicide of acyl amino chiral. |
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T34324 |
Ribulose, L-
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L-Adonose,L-Ribulose,L-Erythro-pentulose,L-erythro-2-Pentulose |
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Ribulose is an important metabolite in pentose interconversions. Ribulose is useful for analyzing L-ribose isomerase, engineering yeast for xylose metabolism, interesting chiral pool compound. |
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T30146 |
Arverapamil
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(R)-Norverapamil,Agi-003,UNII-3J8P56R04P,Rezular |
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Arverapamil is a chiral metabolite of Verapamil. |
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T27793 |
L-alpha-Methylbenzyl isothiocyanate
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L-alpha-Methylbenzyl isothiocyanate is an antioxidant. It induces phase II enzyme activity and is also used as a chiral agent. |
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T20120 |
Acetylmandelic acid, (+)-
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S-Acetylmandelic acid,Mandelic acid, acetate, L- |
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Acetylmandelic acid, (+)- is a chiral derivatizing agent,and used for NMR determination of enantiomeric purity of α-deuterated carboxylic acids, alcohols, and amines. |
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T25714 |
L-Hamamelose
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Hamamelose L-form,L-Ribose, 2-C-(hydroxymethyl)- |
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L-Hamamelose plays a significant role as a chiral building block in synthesizing a wide variety of enantiopure compounds. |
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T36053 |
D-Lysine lactam
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D-Lysine lactam is a chiral building block.1,2It has been used in the synthesis of a chiral antibiotic synthetic intermediate, as well as in the stereoselective synthesis of neurokinin (NK) receptor antagonists.
1.Kumar,... |
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T37155 |
8(R)-HETE
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8(R)-HETE is biosynthesized by lipoxygenation of arachidonic acid in marine invertebrates such as gorgonian corals and starfish. Stereochemical assignment of the (R) enantiomer is based on comparison of chiral HPLC reten... |
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T35462 |
(±)11-HETE
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(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid . The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPL... |
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T37410 |
9(R)-HETE
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9(R)-HETE is an enantiomer which makes up 50% of (±)9-HETE . At a concentration of 300 nM, 9(R)-HETE activates RXRγ-dependent transcription 1.5 fold relative to a control. Stereochemical assignment of the (R) enantiomer ... |
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T35846 |
13(R)-HODE cholesteryl ester
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13(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid ... |
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T35843 |
9(R)-HODE cholesteryl ester
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9(R)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... |
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T35853 |
9(S)-HODE cholesteryl ester
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9(S)-HODE cholesteryl ester was originally extracted from atherosclerotic lesions. It remains uncertain whether the oxidized fatty acid portion of the molecule results from enzymatic lipoxygenation or from random lipid p... |
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T37411 |
9(S)-HETE
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9(S)-HETE is an enantiomer which makes up 50% of (±)9-HETE . There are no reports of 9(S)-HETE occurring as an enzymatic lipoxygenation product. Whereas 12(S)-HETE promotes adhesion of several cell lines to endothelial c... |
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T36558 |
(±)9-HETE
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(±)9-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. The individual R and S isomers of racemic HETEs have been separated and identified using chiral phase HPLC.... |
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T37158 |
8(S)-HETE
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8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0... |
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T2579 |
Reboxetine
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Norebox |
Norepinephrine
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Reboxetine (Norebox) is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. Its mesylate (i.e. methanesulfonate) salt is sold under trade names including Edronax, Norebox, Pr... |
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T60832 |
(S)-Bromoenol lactone
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(S)-Bromoenol lactone ((S)-BEL) inhibits the arachidonate release induced by vasopressin from cultured rat aortic smooth muscle (A10) cells with an IC 50 of 2 μM. (S)-Bromoenol lactone is an irreversible, chiral, mechani... |
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T69740 |
AMG-315
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AMG-315 is a Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes. AMG-315 is a chiral arachidonoyl ethanolamide (AEA) analogue or (13S,1′R)-dimethylanandamide. AMG-315 is a high affinity ligand for the ... |
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T37490 |
11(R)-HETE
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11(R)-HETE is biosynthesized by 11(R)-LOs of the sea urchin, S. purpuratus, and the fresh water hydra, H. vulgaris. The biological activity of 11(R)-HETE relates to oocyte maturation and tentacle regeneration, respective... |
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T36838 |
(R)-Bromoenol lactone
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The phospholipases are an extensive family of lipid hydrolases that function in cell signaling, digestion, membrane remodeling, and as venom components. The calcium-independent phospholipases (iPLA2) are a PLA2 subfamily... |
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T36015 |
PDMP (hydrochloride)
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PDMP is a ceramide analog first prepared in a search for inhibitors of glucosylceramide synthase. PDMP has two adjacent chiral centers (C1 and C2) allowing for the formation of four possible isomers. PDMP contains all fo... |
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T36564 |
(S)-Acenocoumarol
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Acenocoumarol is a short-lived oral anti-coagulant, which, like warfarin, functions by inhibiting vitamin K epoxide reductase. It has higher intrinsic anticoagulant potency than warfarin and phenprocoumon, when evaluated... |
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T36241 |
Arecaidine propargyl ester (hydrobromide)
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Arecaidine propargyl ester is an agonist of M2muscarinic acetylcholine receptors (mAChRs).1It selectively binds to M2over M1, M3, M4, and M5mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0... |
