|
T2296 |
Trelagliptin succinate
|
SYR-472 succinate,SYR472 |
Proteasome
,
DPP-4
|
|
Trelagliptin succinate (SYR-472 succinate) is a long-acting inhibitor of dipeptidyl peptidase-4 (DPP-4), being developed for the treatment of type 2 diabetes (T2D). |
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T19367 |
Hypoglycemic agent 1
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Others
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|
Hypoglycemic agent 1 has an action for lowering blood sugar. It acts as a therapeutic and/or prophylactic agent for diabetes. |
|
T62091 |
Anti-hyperglycemic agent-1
|
|
|
|
Anti-hyperglycemic agent 1 is a potent inhibitor of alpha-glucosidase (IC50: 0.53 μM). anti-Hyperglycemic agent 1 can be used to study diabetes. |
|
T20158 |
Phenformin
|
Debeone,N-Phenethylbiguanide,Insoral,BRN 1977317,Azucaps |
Apoptosis
|
|
Phenformin (BRN 1977317) is a biguanide compound with anticancer and anti-glycemic activity, inhibits skin tumor growth and promotes keratinocyte differentiation and apoptosis. |
|
T8526 |
Metformin
|
1,1-Dimethylbiguanide |
Mitophagy
,
AMPK
,
Autophagy
|
|
Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is comm... |
|
T1458 |
Epalrestat
|
ONO2235 |
Reductase
|
|
Epalrestat (ONO2235), an aldose reductase inhibitor, is well tolerated in Long-term therapy. It can effectually ameliorate the associated symptoms of diabetic neuropathy and delay the progression of the disease, particul... |
|
T69405 |
Metformin embonate
|
|
|
|
Metformin embonate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. |
|
T69049 |
Metformin orotate
|
|
|
|
Metformin orotate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. |
|
T70806 |
Metformin icosapent
|
|
|
|
Metformin icosapent is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. |
|
T26289 |
TRC210258
|
TRC-210258,TRC 210258 |
|
|
TRC210258 is a TGR5 agonist that acts by decreasing glycemic and dyslipidemic cardiovascular risk in animal models of diabesity. |
|
T71222 |
Metformin glycinate
|
|
|
|
Metformin glycinate is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. |
|
TP1584 |
GIP (1-30) amide,human
|
GIP (1-30) amide (Human) |
|
|
GIP (1-30) amide (Human) is an insulin-dependent glucose-dependent polypeptide.The sugar-dependent insulin polypeptide (GIP) is an insulin secreting hormone, which can stimulate the secretion of insulin and reduce the oc... |
|
Fr14395 |
2,2'-Bipyridine
|
|
|
|
2,2'-Bipyridine is a unique bioactive natural product molecular scaffold commonly used in the core structure of many chelating ligands. 2,2'-Bipyridine acts as a bridge in the arrangement of the catalytic center. 2,2'-Bi... |
|
T76041 |
GIP (1-30) amide,human acetate
|
|
|
|
GIP (1-30) amide, human acetate is a fragment of glucose-dependent insulinotropic polypeptide (GIP), an incretin hormone that plays a crucial role in stimulating insulin secretion and mitigating postprandial glycemic exc... |
|
T76263 |
Beinaglutide
|
|
|
|
Beinaglutide, a recombinant human GLP-1 (rhGLP-1) polypeptide, exhibits nearly complete homology with human GLP-1 (7–36). It demonstrates dose-dependent effects in improving glycemic control, reducing food intake, delayi... |
|
T82254 |
GSK-LSD1
|
|
Histone Demethylase
|
|
GSK-LSD1, an LSD1 inhibitor, decreases food consumption and body weight while enhancing insulin sensitivity and glycemic regulation in murine obesity models. Additionally, it mitigates non-alcoholic fatty liver disease (... |
