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T8703 |
YGsy2p-IN-1
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Others
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yGsy2p-IN-1 is a potent yeast glycogen synthase 2 (yGsy2p) and human glycogen synthase 1 (hGYS1) inhibitor. yGsy2p-IN-H23 a pyrazole inhibitor,and is used for glycogen storage diseases (GSDs) |
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T41160 |
Lalistat 2
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Lipase
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Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 μM). |
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T20470 |
Edetic acid
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Ethylenediaminetetraacetic acid,EDTA |
Others
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Edetic acid (Ethylenediaminetetraacetic acid) is a chelating agent commonly used in protein purification, both to eliminate contaminating divalent cations and to inhibit protease activity. |
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T1043 |
Multifungin
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Bromochlorosalicylanilide,Salifungin |
Others
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Antifungal
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Multifungin (Bromochlorosalicylanilide) is an antifungal that studies oral candidiasis. It reduces the number of fungal populations in corn during storage and prevents the formation and accumulation of zearalenone. |
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T0719 |
Tetrabenazine
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Xenazine,Ro 1-9569 |
Others
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Dopamine Receptor
,
Monoamine Transporter
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Tetrabenazine (Ro 1-9569) is a drug formerly used as an antipsychotic and treatment of various movement disorders. Tetrabenazine blocks neurotransmitter uptake into adrenergic storage vesicles and has been used as a high... |
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T40542 |
Sinbaglustat
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ACT-519276,Sinbaglustat,OGT2378 |
Transferase
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Sinbaglustat (OGT2378) (OGT2378) is a dual inhibitor of glucose ceramide synthetase (GCS) and non-lysosomal glucose ceramidase (GBA2).Sinbaglustat is an orally administered N-alkyl iminosugar that crosses the blood-brain... |
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T72072 |
2-benzylsulfanyl-6-methoxy-4-methylquinazoline
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ROS
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2-benzylsulfanyl-6-methoxy-4-methylquinazoline can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity, such as lysosomal storage disease, muscular dystrophy, oxidative stress or rea... |
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T3534 |
Tetrabenazine Racemate
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Nitoman,Ro 1-9569 Racemate,Rubigen,TETRABENAZINE |
Monoamine Transporter
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Tetrabenazine Racemate (Rubigen) is a selective and reversible inhibitor of vesicular monoamine transporter-2 (VMAT-2). Tetrabenazine Racemate blocks neurotransmitter uptake into adrenergic storage vesicles and has been ... |
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T20539 |
Pirimiphos-methyl
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R 33986,AI3-27699,Caswell No. 334B,PP511,Actelic |
AChE
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Parasite
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Pirimiphos-methyl (AI3-27699) is a rapid-acting organophosphorus insecticide and acaricide, causing inhibition of AChE in target organisms. Pirimiphos-methyl is often used for prevention and control of beetles, moths, sn... |
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T4473 |
Ibiglustat
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Venglustat,SAR402671,GZ402671 |
Transferase
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Ibiglustat (GZ402671) is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthe... |
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T111959 |
IFB-088 acetate
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|
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IFB-088 acetate, a benzyl guanidine derivative, is used to treat diseases and cancers associated with the PPP1R15A pathway and associated with protein misfolding stress, Examples include tau disease, synaptic riboprotein... |
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T28064 |
ML207
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ML 207,LLI01-022,ML-207 |
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ML207 inhibits lipid storage in Drosophila melanogaster. |
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T30935 |
Ci-IP3/PM
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CI-IP3 /PM is a cell-permeable caged inositol triphosphate that promotes the release of Ca2+ from internal storage under UV photolysis. |
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T32923 |
Lucerastat
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NBDGJ |
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Lucerastat is a very effective and selective α-gal A (α-D-galactosidase) inhibitor for the treatment of lipid storage diseases and Fabry disease. |
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T9097L |
Guanadrel Sulfate
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CL 1388R,U 28288D,CHEBI:5556,Hylorel,Hyloride |
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Guanadrel Sulfate is a postganglionic adrenergic blocking agent. The uptake of guanadrel and storage in sympathetic neurons occurs via the norepinephrine pump or transporter. |
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T40046 |
UGT8-IN-1
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UGT8-IN-1 |
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UGT8-IN-1 is a brain-permeable and orally-active inhibitor that specifically targets the ceramide galactosyltransferase enzyme (UGT8). By inhibiting UGT8, this compound has the potential to be employed in research pertai... |
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T36721 |
Dehydro Amlodipine (fumarate)
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Dehydro amlodipine is a potential impurity found in commercial preparations of amlodipine. It is a degradation product formed during storage or when amlodipine is subjected to oxidative or acidic conditions or undergoes ... |
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T28129 |
Naltalimide
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TRK-130,TRK 130,TRK130 |
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Naltalimide is a unique µ-opioid receptor partial agonist. Naltalimide also enhances the bladder storage function by modulating the afferent limb of the micturition reflex through µ-opioid receptors in the spinal cord. |
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T26260 |
Tetrabenazine methanesulfonate
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NSC169886,NSC 169886,NSC-169886 |
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Tetrabenazine methanesulfonate is a medicine formerly utilized as an antipsychotic and therapy for various movement disorders. Tetrabenazine methanesulfonate blocks neurotransmitter uptake into adrenergic storage vesicle... |
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T69143 |
S 332
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S 332 is an adrenergic beta3-agonist that is more potent in increasing the urinary storage volume than clenbuterol and less potent in inhibiting the contractile force of urinary bladder at micturition reflex than clenbut... |
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T75368 |
MTSEA-Fluorescein
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MTSEA-Fluorescein is a fluorescent probe that can be used for ion channel research [1] . Storage: protect from light . |
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T37853 |
Cholesteryl Lignocerate
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Cholesteryl lignocerate is a cholesterol ester that has been found in human meibum. Cholesteryl lignocerate can be hydrolyzed by cellular extracts from cultured human skin fibroblasts isolated from healthy individuals bu... |
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T82340 |
Ganglioside GM2
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Ganglioside GM2, a human tumor antigen (OFA-I-1), is the primary lysosomal storage compound in Tay-Sachs disease [1] [2]. |
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T40456 |
8-Bromoadenosine 5'-triphosphate tetrasodium
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8-Br-ATP tetrasodium,8-Bromoadenosine 5'-triphosphate tetrasodium |
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8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is a tetrasodium ATP analogue, serving as a vital element for energy storage and metabolic processes in living organisms. ATP, a central component in vi... |
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T75653 |
(±)-Columbianetin
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Dihydrooroselol |
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Columbianetin, a phytoalexin found in celery (Apium graveolens), plays a crucial role in the plant's resistance to pathogens during storage. It demonstrates significant anti-fungal and anti-inflammatory properties [1] [2... |
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T70336 |
Nizubaglustat
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Nizubaglustat acts as an inhibitor of Ceramide Glucosyltransferase, also known as Glucosylceramide Synthase (GCS), and additionally inhibits GBA2, which is involved in neuropathological lysosomal storage disorders. |
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T75369 |
DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS
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DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye utilized as a fluorogenic substrate for aspartyl proteinase from the human malaria parasite [1]. It requires protection from light during storage. |
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T74013 |
Geldanamycin-FITC
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Geldanamycin-FITC, a fluorescent probe derived from Geldanamycin, is applicable in fluorescence polarization assays to identify HSP90 inhibitors and can be employed to detect cell surface HSP90 [1] [2] [3]. It requires p... |
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T77200 |
2-Aminopurine dihydrochloride
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2-Aminopurine dihydrochloride, a fluorescent analog of guanosine, serves as a fluorescence probe for analyzing nucleic acid structure and dynamics. When incorporated into DNA, it exhibits quenched fluorescence [1] [2]. F... |
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T38674 |
YGsy2p-IN-H23
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yGsy2p-IN-H23 |
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yGsy2p-IN-H23 is a potent, first-in-class inhibitor specifically designed to target yeast glycogen synthase 2 (yGsy2p). It demonstrates an IC50 value of 875 μM for human glycogen synthase 1 (hGYS1). This compound binds p... |
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T74626 |
BBR-BODIPY
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BBR-BODIPY, a fluorescent probe, facilitates the screening of its interactions with targeted cells, induces apoptosis, and alters the expression of apoptosis-related proteins [1]. Storage instructions include protection ... |
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T74073 |
Cyanine 5 Tyramide methyl indole
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Cyanine 5 Tyramide (Tyramide-Cy5) methyl indole, a red fluorescent dye, is used as a reporter fluorescent substrate for horseradish peroxidase (HRP)-catalyzed deposition, facilitating signal amplification in immunoassay ... |
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T35809 |
C20 Sphingomyelin (d18:1/20:0)
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C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlate... |
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T37493 |
11-trans Leukotriene D4
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11-trans Leukotriene D4 |
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11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency fo... |
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T35804 |
C16 Lactosylceramide (d18:1/16:0)
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C16 Lactosylceramide is an endogenous bioactive sphingolipid. It forms membrane microdomains with Lyn kinase and the αi subunits of inhibitory G protein-coupled receptors (GPCRs), suggesting a role in cell signaling. Pla... |
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T75373 |
Bz-FVR-AMC
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Bz-FVR-AMC is a fluorogenic substrate utilized for procathepsin, demonstrating a catalytic efficiency (k_cat/K_m) of 1070 mM^-1 s^-1. Notably, elevated levels of Bz-FVR-AMC can inhibit the substrate [1] [2]. For storage,... |
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T81820 |
Meso-Benzothiazole-BODIPY 505/515
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Meso-Benzothiazole-BODIPY 505/515, a boron dipyrromethene (BODIPY)-based fluorescent probe, is utilized in autophagy research, particularly for studying Alzheimer's disease, lysosomal storage disorders, and neurodegenera... |
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T75334 |
Methyl Green
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Methyl Green, a potent fluorescent dye, serves as a DNA stain for cells and electrophoretic gels. It facilitates direct measurement of viability via microscopy and flow cytometry, exhibiting peaks at 633 and 677 nm [1] [... |
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T73936 |
HKSOX-1 (5/6-mixture)
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|
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HKSOX-1, a fluorescent probe designed for the imaging and detection of endogenous superoxide in live cells and in vivo, demonstrates outstanding selectivity and sensitivity towards the superoxide anion radical [1]. For s... |
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T73604 |
Methyl Green zinc chloride
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Methyl Green Zinc Chloride, a potent fluorescent dye, is utilized for staining DNA in cells and electrophoretic gels. It serves as a direct measure of viability through microscopy and flow cytometry, exhibiting peaks at ... |
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T79406 |
Tyrosinase-IN-14
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Tyrosinase
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Tyrosinase-IN-14 (compound 7m), a tyrosinase inhibitor, modulates the enzyme's secondary structure to diminish its catalytic function, exhibits low cytotoxicity, and possesses anti-browning properties that effectively pr... |
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T19264 |
D-Methionine sulfoxide hydrochloride
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D-Methionine sulfoxide hydrochloride (21056-56-4 free base) |
Others
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D-methionine sulfoxide hydrochloride is the D-isomer of methionine sulfoxide hydrochloride. Methionine sulfoxide is the oxidation product of methionine. Methionine is a restrictive amino acid in milk or legume proteins a... |
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T75341 |
Biotin-16-dUTP trisodium
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Biotin-16-deoxyuridine-5'-triphosphate (Biotin-16-dUTP) trisodium serves as an enzymatically incorporable substitute for its natural analog, dTTP, in DNA/cDNA synthesis, facilitating the production of biotinylated DNA pr... |
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T75372 |
BODIPY FL Thapsigargin
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BODIPY FL Thapsigargin, a potent green fluorescent dye, effectively inhibits intracellular SERCA-type Ca 2+ pumps localized in the sarcoplasmic/endoplasmic reticulum. It is utilized to investigate thapsigargin binding si... |
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T31292 |
Decalin
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bicyclo[4.4.0]decane,decahydronaphthalene |
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Decalin (decahydronaphthalene, also known as bicyclo[4.4.0]decane), a bicyclic organic compound, is an industrial solvent. A colorless liquid with an aromatic odor, it is used as a solvent for many resins or fuel additiv... |
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T75326 |
ATP ditromethamine
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ATP ditromethamine (Adenosine 5'-triphosphate ditromethamine), a vital in vivo energy storage and metabolic constituent, fuels metabolic pumps and acts as a cellular coenzyme. It also plays a crucial role as an endogenou... |
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T75370 |
CellTracker Blue CMF2HC Dye
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CellTracker Blue CMF2HC Dye, a blue dye suitable for two-channel nuclei acid sequencing using blue and purple excitation light (450-460 nm/400-405nm or 415-450 nm/480-525nm), facilitates rapid determination of microorgan... |
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T75325 |
ATP dimagnesium
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Adenosine 5'-triphosphate (ATP) dimagnesium, a pivotal molecule in energy storage and metabolism, fuels metabolic pumps and acts as a coenzyme within cells. Additionally, it plays a significant role as an endogenous sign... |
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T37118 |
ADP-Glucose (sodium salt)
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ADPG,Adenosine-5'-diphosphoglucose,ADP-Glucose (sodium salt) |
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ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria.... |
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T37802 |
Phospho-L-Arginine (lithium salt hydrate)
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Phospho-L-arginine is a phosphorylated form of L-arginine and a highly diffusible, high-energy metabolite and phosphagen involved in energy storage in invertebrates including crustaceans, insects, and Trypanosoma species... |
