ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T1152 | Albendazole | 54965-21-8 | 98% |
|
| Albendazole is used as a drug indicated for the treatment of a variety of worm infestations. | ||||
| T1939 | DMOG | 89464-63-1 | 98% |
|
| DMOG, an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase. | ||||
| T1637 | Deferoxamine Mesylate | 138-14-7 | 98% |
|
| Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also is an inhibitor of ferroptosis. | ||||
| T3816 | Velutin | 25739-41-7 | 98% |
|
| Velutin shows the strongest inhibitory effect in NF-κB activation and exhibits the greatest effects in blocking the degradation of inhibitor of NF-κB as well as ... | ||||
| T4106 | MK-8617 | 1187990-87-9 | 98% |
|
| MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM). | ||||
| T6961 | PX-478 | 685898-44-6 | 98% |
|
| PX-478 2HCl is an orally active, and selective inhibitor of hypoxia-inducible factor-1α (HIF-1α). | ||||
| T6381 | Amifostine trihydrate | 112901-68-5 | 98% |
|
| Amifostine is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin. | ||||
| T12675L | PT2399 | 1672662-14-4 | 98% |
|
| PT2399 shows effective antitumor activity in vivo. PT2399 is an effective and selective HIF-2α antagonist, which directly binds to the HIF-2α PAS B domain (IC50:... | ||||
| T3289 | Amifostine | 20537-88-6 | 98% |
|
| Amifostine anhydrous is a cytoprotective agent, acts as a free radical scavenging activity. | ||||
| T11561 | HIF-2α-IN-2 | 1672666-82-8 | 98% |
|
| HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay). | ||||
| T9627 | PHD-1-IN-1 | 2009343-14-8 | 98% |
|
| PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM). | ||||
| T1101 | Minocycline hydrochloride | 13614-98-7 | 98% |
|
| Minocycline is a tetracycline antibiotic with excellent absorption and tissue penetration that is used for several bacterial infections as well as treatment of a... | ||||
| T50099 | HIF-2α-IN-4 | 882268-69-1 | 98% |
|
| HIF-2a translation inhibitor is a compound used as a molecular building block. | ||||
| T1141 | Fenbendazole | 43210-67-9 | 98% |
|
| Fenbendazole is an antinematodal benzimidazole used in veterinary medicine. | ||||
| T7802 | M1001 | 874590-32-6 | 98% |
|
| M1001 is a HIF-2α agonist. | ||||
| T3S2344 | β,β-Dimethylacrylshikonin | 24502-79-2 | 98% |
|
| 1. Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combine... | ||||
| T11589 | Hydroxycitric acid tripotassium hydrate | 6100-05-6 | 98% |
|
| Potassium citrate monohydrate effectively inhibits stones formation and also inhibits HIF, and has antioxidation, anti-inflammation, and anti-tumor effects. Hydr... | ||||
| T5176 | Desidustat | 1616690-16-4 | 98% |
|
| Desidustat is an inhibitor of HIF hydroxylase. | ||||
| T29797 | AKB-6899 | 1007377-55-0 | 98% |
|
| AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macr... | ||||
| T21653 | 1,4-DPCA | 331830-20-7 | 98% |
|
| 1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 µM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HI... | ||||
