Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 17,000 | |||
5 mg | 在庫あり | ¥ 41,000 | |||
10 mg | 在庫あり | ¥ 66,000 | |||
25 mg | 在庫あり | ¥ 111,500 | |||
50 mg | 在庫あり | ¥ 159,000 | |||
100 mg | 在庫あり | ¥ 226,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 45,500 |
説明 | AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth. |
別名 | AKB6899 |
分子量 | 290.25 |
分子式 | C14H11FN2O4 |
CAS No. | 1007377-55-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (327.30 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AKB-6899 1007377-55-0 Angiogenesis Chromatin/Epigenetic Metabolism Tyrosine Kinase/Adaptors HIF VEGFR HIF/HIF Prolyl-Hydroxylase antiangiogenic Inhibitor antitumor AKB 6899 HIF-PH HIF-2α sVEGFR-1 HIFs AKB6899 inhibit Hypoxia-inducible factors PHD3 inhibitor