HSP

Heat shock proteins (HSP) are a family of proteins that are produced by cells in response to exposure to stressful conditions. They were first described in relation to heat shock, but are now known to also be expressed during other stresses including exposure to cold, UV light and during wound healing or tissue remodeling. Many members of this group perform chaperone functions by stabilizing new proteins to ensure correct folding or by helping to refold proteins that were damaged by the cell stress.

Cat. No.	製品名	CAS No.	Purity
T10860	Col003	328565-16-8	98%
T10860	Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM). It can be used for the investig...
TP1496L	P5 Ligand for Dnak and DnaJ acetate	TP1496L	98%
TP1496L	p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40).
T20510	Novobiocin	303-81-1	98%
T20510	Novobiocin is an orally active and potent antibiotic.Novobiocin is a DNA gyrase inhibitor and heat shock protein 90 (Hsp90) antagonist with inhibitory effects on...
TQ0280	Feretoside	27530-67-2	98%
TQ0280	Feretoside is a natural product extracted from the barks of E. ulmoides. It is an HSP inducer.
T12896L	Shepherdin 79-87 acetate		98%
T12896L	Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.
T6960L	PU-H71 HCl	2095432-24-7	98%
T6960L	PU-H71 HCL is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT.PU-H71 HCL shows antitumor activ...
T3487	HSP70-IN-1	1268273-90-0	98%
T3487	HSP70-IN-1 is a heat shock protein (HSP) inhibitor and inhibits the growth of Kasumi-1 cells (IC50: 2.3 μM).
T6343	Geldanamycin	30562-34-6	98%
T6343	Geldanamycin, an HSP90 inhibitor (Kd: 1.2 μM), specifically disrupts glucocorticoid receptor (GR)/HSP association.
T70353	JG-231	1627126-59-3	98%
T70353	JG-231 is a JG-98 analog with anticancer activity.JG-231 inhibits the MDA-MB-231 xenograft tumor model of triple-negative breast cancer (TNBC).JG-231 inhibits th...
T72076	H2-Gamendazole	877768-84-8	98%
T72076	H2-Gamendazole is a novel compound for spermatogenesis inhibition and cancer therapy as an inhibitor of heat shock proteins and/or elongation factor 1 alpha, and...
T21872	CCT018159	171009-07-7	98%
T21872	CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90β and yeast Hsp90 with IC50s of 3.2 and 6.6 μM, r...
T2230	Paeoniflorin	23180-57-6	98%
T2230	Paeoniflorin is a herbal constituent extracted from the root of Paeonia albiflora Pall.
T8668	HM03	500565-15-1	98%
T8668	HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.
T27193	DN401	2135749-60-7	98%
T27193	DN401 is a potent TRAP1 and Hsp90 Inhibitor( IC50 = 79 nM for TRAP1, IC50 = 698 nM for Hsp90) with potent anticancer activity.
T3527	TRC051384	867164-40-7	98%
T3527	Inducer of heat shock protein Hsp70; reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke. Activates heat...
T8189	Dihydroberberine	483-15-8	98%
T8189	Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channel...
T0756	Ethoxyquin	91-53-2	98%
T0756	Ethoxyquin is an antioxidant used in animal feeds.
T6118	NVP-HSP990	934343-74-5	98%
T6118	NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).
T7261	Grp94 Inhibitor-1	2234897-35-7	98%
T7261	Grp94 Inhibitor-1 is a potent, selective Grp94 inhibitor (IC50 : 2 nM).
T7265	HSP27 inhibitor J2	2133499-85-9	98%
T7265	HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the H...