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LPA Receptor

Lysophosphatidic acid (LPA) receptors are a group of G-protein-coupled receptors that are currently divided into six subtypes: LPA1, LPA2, LPA3, LPA4, LPA5 and LPA6. They belong to a family of lysophospholipid receptors that include S1P receptors.
Cat. No. 製品名 CAS No. Purity Chemical Structure
T9699 TAK-615 1664335-55-0 98%
TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.
T69647 UCM-05194 2411412-36-5 98%
UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.
T2000 AM095 1345614-59-6
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
T7393 ONO-7300243 638132-34-0
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 µM).
T22835 H2L5186303 139262-76-3 97.23%
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
T22070 DBIBB 1569309-92-7 97.26%
DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of...
T6347 Ki16198 355025-13-7 97.6%
Ki16198 is an orally available LPA receptor antagonist and is a methyl ester derivative of Ki16425. It inhibits LPA1- and LPA3-induced inositol phosphates with K...
T15796 LX-1031 945976-76-1 97.97%
LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.
T7689 Tetradecyl Phosphonate 4671-75-4 98%
Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors.
T22812 GRI977143 325850-81-5 98.07%
GRI977143 is a selective and non-lipid agonist of LPA2 (EC50 = 3.3 μM). GRI977143 inhibits the activation of caspases 3, 7, 8, and 9 and and reduces DNA fragment...
T6108 Ki16425 355025-24-0 98.54%
Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
T4016 BMS-986020 1257213-50-5 98.61%
BMS-986020 (AM152) is a selective antagonist of LPA1.
T12684 Radioprotectin-1 1622006-09-0 98.75%
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
T23438 TC LPA5 4 1393814-38-4 99.05%
TC LPA5 4 is a LPA5 receptor antagonist.
T21654 1-Oleoyl lysophosphatidic acid sodium 325465-93-8 99.24%
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2
T22834 H2L 5765834 420841-84-5 99.47%
H2L 5765834 is a lysophosphatidic acid receptors antagonist
T4278 AM966 1228690-19-4 99.49%
AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.
T15785 LPA1 receptor antagonist 1 1396006-71-5 99.58%
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopa...
T4521 Edg-2 receptor inhibitor 1 1195941-38-8 99.69%
Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).
T39647 BMS-986278 2170126-74-4 99.86%
BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1, respec...
TAK-615
T9699
TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.
UCM-05194
T69647
UCM-05194 is a selective LPA1 receptor agonist that can improve neuropathic pain and can be used in the study of progressive system diseases.
AM095
T2000
AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.
ONO-7300243
T7393
ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 µM).
H2L5186303
T22835
H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.
DBIBB
T22070
DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of...
Ki16198
T6347
Ki16198 is an orally available LPA receptor antagonist and is a methyl ester derivative of Ki16425. It inhibits LPA1- and LPA3-induced inositol phosphates with K...
LX-1031
T15796
LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally.
Tetradecyl Phosphonate
T7689
Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors.
GRI977143
T22812
GRI977143 is a selective and non-lipid agonist of LPA2 (EC50 = 3.3 μM). GRI977143 inhibits the activation of caspases 3, 7, 8, and 9 and and reduces DNA fragment...
Ki16425
T6108
Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.
BMS-986020
T4016
BMS-986020 (AM152) is a selective antagonist of LPA1.
Radioprotectin-1
T12684
Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.
TC LPA5 4
T23438
TC LPA5 4 is a LPA5 receptor antagonist.
1-Oleoyl lysophosphatidic acid sodium
T21654
1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2
H2L 5765834
T22834
H2L 5765834 is a lysophosphatidic acid receptors antagonist
AM966
T4278
AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.
LPA1 receptor antagonist 1
T15785
LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a selective and potent lysophosphatidic acid (LPA1) receptor antagonist (IC50 : 25 nM) for the study of idiopa...
Edg-2 receptor inhibitor 1
T4521
Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).
BMS-986278
T39647
BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1, respec...
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