ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T22812 | GRI977143 | 325850-81-5 | 98% |
|
| GRI977143 is a selective and non-lipid agonist of LPA2 (EC50 = 3.3 μM). GRI977143 inhibits the activation of caspases 3, 7, 8, and 9 and and reduces DNA fragment... | ||||
| T2000 | AM095 | 1345614-59-6 | 98% |
|
| AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively. | ||||
| T4278 | AM966 | 1228690-19-4 | 98% |
|
| AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release. | ||||
| T9699 | TAK-615 | 1664335-55-0 | 98% |
|
| TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors. | ||||
| T21654 | 1-Oleoyl lysophosphatidic acid sodium | 325465-93-8 | 98% |
|
| 1-Oleoyl lysophosphatidic acid sodium salt is an Endogenous agonist of LPA1 and LPA2 | ||||
| T7393 | ONO-7300243 | 638132-34-0 | 98% |
|
| ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 µM). | ||||
| T22835 | H2L5186303 | 139262-76-3 | 98% |
|
| H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment. | ||||
| T6347 | Ki16198 | 355025-13-7 | 98% |
|
| Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μ... | ||||
| T15796 | LX-1031 | 945976-76-1 | 98% |
|
| LX-1031 is an effective inhibitor of tryptophan 5-hydroxylase. LX-1031 decreases serotonin (5-HT) synthesis peripherally. | ||||
| T7689 | Tetradecyl Phosphonate | 4671-75-4 | 98% |
|
| Tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (LPA1), LPA2, and LPA3 receptors. | ||||
| T6108 | Ki16425 | 355025-24-0 | 98% |
|
| Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively. | ||||
| T4016 | BMS-986020 | 1257213-50-5 | 98% |
|
| BMS-986020 is a selective antagonist of LPA1. | ||||
| T12684 | Radioprotectin-1 | 1622006-09-0 | 98% |
|
| Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action. | ||||
| T23438 | TC LPA5 4 | 1393814-38-4 | 98% |
|
| TC LPA5 4 is a LPA5 receptor antagonist. | ||||
| T22834 | H2L 5765834 | 420841-84-5 | 98% |
|
| H2L 5765834 is a lysophosphatidic acid receptors antagonist | ||||
| T4521 | Edg-2 receptor inhibitor 1 | 1195941-38-8 | 98% |
|
| Edg-2 receptor inhibitor 1 is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM). | ||||
| T10293 | AM095 free acid | 1228690-36-5 | 98% |
|
| AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1). | ||||
| T14335 | ASP6432 | 1282549-08-9 | 98% |
|
| ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively. | ||||
| T11875 | LPA2 antagonist 2 | 36840-10-5 | 98% |
|
| LPA2 antagonist 2 is ＞480-fold more selective than LPA3 (IC50 of 13.85 μM).LPA2 antagonist 2 is a selective LPA2 antagonist with an IC50 of 28.3 nM and a Ki of 2... | ||||
| T22070 | DBIBB | 1569309-92-7 | 98% |
|
| DBIBB is a non-lipid agonist of specific lysophosphatidic acid (LPA2) type 2 G-protein-coupled receptor. It is a potentially active molecule for the treatment of... | ||||
