Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in many pathological conditions including ischemia and reperfusion injury, asthma-related inflammation, and atherogenesis.
説明 | TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in many pathological conditions including ischemia and reperfusion injury, asthma-related inflammation, and atherogenesis. |
分子量 | 201.24 |
分子式 | C11H7NOS |
CAS No. | 420849-22-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (273.31 mM)
You can also refer to dose conversion for different animals. 詳細
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TIQ-A 420849-22-5 Chromatin/Epigenetic DNA Damage/DNA Repair PARP poly ADP ribose polymerase ADP-ribosyltransferase TIQA Inhibitor TIQ A inhibit tankyrases ADP-ribosylation poly-ART inhibitor