Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 21,500 | |||
5 mg | 在庫あり | ¥ 52,500 | |||
10 mg | 在庫あり | ¥ 85,500 | |||
25 mg | 在庫あり | ¥ 150,500 | |||
50 mg | 在庫あり | ¥ 229,000 | |||
100 mg | 在庫あり | ¥ 342,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 58,000 |
説明 | (E/Z)-GSK5182 (GSK5182(Z/E)) is a racemic mixture comprising (E)-GSK5182 and (Z)-GSK5182 isomers. It acts as a highly selective and orally active inverse agonist for the estrogen-related receptor γ (ERRγ), demonstrating potency with an IC50 of 79 nM. Additionally, GSK5182 is known to induce the generation of reactive oxygen species (ROS) in hepatocellular carcinoma. |
別名 | GSK5182(Z/E) |
分子量 | 417.54 |
分子式 | C27H31NO3 |
CAS No. | T7709 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 95 mg/mL (227.52 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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(E/Z)-GSK5182 T7709 Endocrinology/Hormones Immunology/Inflammation ROS Estrogen/progestogen Receptor (E/Z)GSK5182 GSK5182(Z/E) (E/Z) GSK5182 (E/Z)-GSK 5182 (E/Z)-GSK-5182 Inhibitor inhibitor inhibit