Powder: -20°C for 3 years | In solvent: -80°C for 1 year
XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 13,500 | |||
10 mg | 在庫あり | ¥ 22,500 | |||
25 mg | 在庫あり | ¥ 43,500 | |||
50 mg | 在庫あり | ¥ 79,500 | |||
100 mg | 在庫あり | ¥ 118,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 18,500 |
説明 | XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα). |
ターゲット&IC50 | ERRα:0.37 μM (IC50) |
キナーゼ試験 | The inhibition of SHP2 from the tested compounds (SHP099) concentrations varying from 0.003-100 μM is monitored using an assay in which 0.5 nM of SHP2 is incubated with of 0.5 μM of peptide IRS1_pY1172(dPEG8)pY1222. After 30-60 minutes incubation at the surrogate substrate, DiFMUP is added to the reaction and incubated at 25 °C for 30 minutes. The reaction is then quenched by the addition of 5 μL of a 160 μM solution of bpV(Phen). The fluorescence signal is monitored using a microplate reader using excitation and emission wavelengths of 340 nm and 450 nm, respectively[1]. |
分子量 | 596.42 |
分子式 | C23H13F9N4O3S |
CAS No. | 725247-18-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 21 mg/mL (35.21 mM), Sonication and heating are recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
XCT790 725247-18-7 Autophagy Endocrinology/Hormones Estrogen Receptor/ERR Estrogen/progestogen Receptor XCT 790 Inhibitor XCT-790 inhibit inhibitor