Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 20,000 | |||
10 mg | 在庫あり | ¥ 27,500 | |||
25 mg | 在庫あり | ¥ 44,000 | |||
50 mg | 在庫あり | ¥ 64,500 | |||
100 mg | 在庫あり | ¥ 95,500 |
説明 | (Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor (Ki: 4 nM; EC50: 12 nM), with anti-obesity and antidepressant effects. |
ターゲット&IC50 | 5-HT2C receptor:12 nM (EC50), 5-HT2C receptor:4 nM(Ki) |
In vivo | In male C57BL/6J mice, (Rac)-WAY-161503 (3-30 mg/kg; i.p.) treatment dose-dependently decreases locomotor activity, an effect that is blocked by the 5-HT2C/2B antagonist SER-082. Additionally, in the 5-HT2A KO mice, the decreased locomotor activity produced by 10 mg/kg DOI is potentiated [1]. |
分子量 | 272.13 |
分子式 | C11H11Cl2N3O |
CAS No. | 75704-24-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90 mg/mL (330.7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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(Rac)-WAY-161503 75704-24-4 GPCR/G Protein Neuroscience 5-HT Receptor WAY-161503 (Rac) WAY 161503 WAY161503 WAY 161503 (Rac)WAY161503 Inhibitor inhibitor inhibit