Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 13,000 | |||
5 mg | 在庫あり | ¥ 32,000 | |||
10 mg | 在庫あり | ¥ 51,000 | |||
25 mg | 在庫あり | ¥ 102,500 | |||
50 mg | 在庫あり | ¥ 151,500 | |||
100 mg | 在庫あり | ¥ 215,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 41,000 |
説明 | (S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor. |
ターゲット&IC50 | HER2 exon 20 YVMA insertion:21.2 nM (IC50), EGFR (exon 20 ASV insertion):51.9 nM (IC50), EGFR (L858R/T790M):1 nM (IC50), EGFR (exon 20 NPH):51.2 nM (IC50) |
別名 | N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide, DZD9008 |
分子量 | 584.08 |
分子式 | C29H35ClFN7O3 |
CAS No. | 2370013-49-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/ml (94.16 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
(S)-Sunvozertinib 2370013-49-1 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR HER HER1 Her2 (S)Sunvozertinib mutant forms of ErbB Epidermal growth factor receptor lung DZD 9008 ErbB-1 DZD-9008 inhibit Btk breast cancer (S)-DZD9008 Inhibitor N-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide Sunvozertinib Bruton tyrosine kinase DZD9008 (S) Sunvozertinib inhibitor