Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 7,500 | |||
25 mg | 在庫あり | ¥ 15,000 | |||
50 mg | 在庫あり | ¥ 24,500 | |||
100 mg | 在庫あり | ¥ 38,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 8,000 |
説明 | 1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. This compound can be used with cells in culture and in animals. |
ターゲット&IC50 | PARP1:0.39 μM |
分子量 | 161.16 |
分子式 | C9H7NO2 |
CAS No. | 5154-02-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 1 mg/mL
Ethanol: 20 mg/mL
DMSO: 55 mg/mL (341.28 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
1,5-Isoquinolinediol 5154-02-9 Chromatin/Epigenetic DNA Damage/DNA Repair PARP diabetic 1188540 oxidative retinopathy 1,5 Isoquinolinediol stress inhibit NADPH Inhibitor 1,5Isoquinolinediol oxidase poly ADP ribose polymerase inhibitor