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Search Results for " oxidative "

ターゲット

Others Reactive Oxygen Species Antifungal

297

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206

天然化合物

リコンビナントタンパク質

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カタログ番号	製品名	別名	ターゲット
T5116	Iprodione		Others , Reactive Oxygen Species , Antifungal
	Iprodione is a fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes.		Others , Reactive Oxygen Species , Antifungal
T25049	Allethrin		BCL , Caspase
	Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.		BCL , Caspase
T7845	BTZO-1		Apoptosis
	BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.		Apoptosis
T0734	Antipyrine	Phenazone,Phenazon	COX
	Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver.		COX
T7042	1,5-Isoquinolinediol		PARP
	1, 5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC50: 0.39 μM). The poly(ADP-ribose) polymerases (PARPs) form a family of enzymes with roles in DNA repair and apoptosis. 1, 5-Isoquinolinediol...		PARP
T8391	Cesium chloride	CsCl	Potassium Channel
	Cesium chloride (CsCl) is considered to be the most toxic of the alkali chlorides, inhibiting fungal growth.		Potassium Channel
T60034	TH1085		Others
	TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).		Others
T21902	ML351		Lipoxygenase
	ML351 is a potent and selective inhibitor of human 15-lipoxygenase-1 (15 LOX)(IC50: 200 nM).		Lipoxygenase
T8500	VLX600		OXPHOS , Mitochondrial Metabolism , Autophagy
	VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.		OXPHOS , Mitochondrial Metabolism , Autophagy
T7093	Rafoxanide		CDK , Parasite
	Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.		CDK , Parasite
T5486	RU.521	RU320521	DNA , cGAS
	RU.521 (RU3205217) is a potent dsDNA inhibitor (IC50 : 700 nM), inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.		DNA , cGAS
T5345	V-9302		Others
	V-9302 (V9302) is a competitive antagonist of transmembrane glutamine flux that selectively and potently targets the amino acid transporter ASCT2 (IC50: 9.6 uM).		Others
T14042	4-P-PDOT	4-phenyl-2- propionamidotetralin	Melatonin Receptor , MT Receptor
	4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.		Melatonin Receptor , MT Receptor
T5827	BI-6C9		Apoptosis , Others , Mitochondrial Metabolism
	BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.		Apoptosis , Others , Mitochondrial Metabolism
T6708	Tolcapone	Tasmar,Ro 40-7592	Apoptosis , Beta Amyloid , Transferase
	Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopa and carbidopa.		Apoptosis , Beta Amyloid , Transferase
T0412	Idebenone	CV-2619	Apoptosis , Antioxidant , Mitochondrial Metabolism
	Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).		Apoptosis , Antioxidant , Mitochondrial Metabolism
T9211	Mito-LND	Mito-Loidamine	OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy
	Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
T23550	YM-750	YM 750	Acyltransferase
	YM-750 is a potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), with an IC50 value of 0.18 μM. ACAT is an enzyme that catalyzes the conversion of cholesterol and long-chain fatty-acyl-coenzyme A into cholest...		Acyltransferase
TP1929L1	Saralasin acetate(34273-10-4 free base)		RAAS
	Saralasin acetate is a Non-selective angiotensin II antagonist.		RAAS
T40192	DGTP	2'-Deoxyguanosine-5'-triphosphate	Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
	dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and 8-O-dGTP.		Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis
T5337	IACS-010759	IACS-10759,IACS 10759,IACS10759	Apoptosis , Others , Mitochondrial Metabolism
	IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.		Apoptosis , Others , Mitochondrial Metabolism
T5371	L-BUTHIONINE-(S,R)-SULFOXIMINE	L-Butionine sulfoximine	Others , Ferroptosis
	L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cells by depleting GSH.		Others , Ferroptosis
T39308	Boc-Asp(OMe)-fluoromethyl ketone	Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK	Caspase
	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemot...		Caspase
T13920L	Terlipressin Acetate	Terlipressin diacetate anhydrous,Terlipressin acetate anhydrous	Vasopressin Receptor
	Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-in...		Vasopressin Receptor
T23146	PHA 568487 free base	PHA 568487	AChR
	The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated lia...		AChR
T6170	Elesclomol	STA-4783	Apoptosis , HSP , Reactive Oxygen Species
	Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier. Elesclomol induces apoptosis in tumor cells and is used in copper death related studies. Elesclomol also inhibits FDX1-medi...		Apoptosis , HSP , Reactive Oxygen Species
T9516	Binodenoson	WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos	Adenosine Receptor
	Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres...		Adenosine Receptor
T22309	2,5-Dimethyl-3(2H)-furanone	2,5-Dimethyl-2,3-dihydrofuran-3-one	Others
	2,5-Dimethyl-3(2H)-furanone (2,5-Dimethyl-2,3-dihydrofuran-3-one) is a non-genotoxic flavoring substance [1].		Others
T1487	Fluvastatin sodium	XU 62320 sodium,XU-62-320,Fluvastatin sodium salt	Ferroptosis , HMG-CoA Reductase , Autophagy
	Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol lowering agent.		Ferroptosis , HMG-CoA Reductase , Autophagy
T20684	2',7'-Dichlorofluorescein diacetate	Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,DCFDA	Others
	2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein), a cell-permeable fluorogenic probe, is useful for the detection of nitric oxide (NO) and reactive oxygen species (ROS) and for the determination of the d...		Others
T8842	IMT1B	3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-,LDC203974	Others , DNA/RNA Synthesis
	IMT1B (LDC203974) is an orally administered, specific noncompetitive allosteric inhibitor of the mitochondrial RNA polymerase (POLRMT), effectively suppressing mitochondrial DNA (mtDNA) expression. This action confers it...		Others , DNA/RNA Synthesis
T1244	Celiprolol hydrochloride	Selecor,Selectrol	Adrenergic Receptor
	Celiprolol hydrochloride (Selectrol) is a cardioselective beta-1 adrenergic antagonist that has intrinsic sympathomimetic activity. It is used in the management of ANGINA PECTORIS and HYPERTENSION.		Adrenergic Receptor
T14999	CORM-401		Others
	CORM-401 is an oxidant-sensitive CO-releasing molecule. It can be used in oxidative stress-mediated pathologies and the research of inflammatory.		Others
T10512	Prenyl-IN-1		Transferase
	Prenyl-IN-1 is a potent and selective prenylation inhibitor of geranylgeranyltransferase or farnesyltransferase.Prenyl-IN-1 shows anti-oxidative stress effects in a Parkinson's model. Prenyl-IN-1 showed anti-oxidative st...		Transferase
T2225	4-Hydroxyantipyrine		COX
	4-Hydroxyantipyrine is formed during oxidative deamination of aminopyrine.		COX
T20543	Flurochloridone	R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401	Apoptosis , Reactive Oxygen Species
	Flurochloridone (R 40244) is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.		Apoptosis , Reactive Oxygen Species
T25441	Fructosylvaline	Fru-val,N-Fructosyl Valine	Others
	Fructosylvaline（Fru-val） is present in miso, white wine and sake and has been associated with oxidative browning of white wine and sake.		Others
T18976	Dihydrofluorescein diacetate	Diacetyldihydrofluorescein	Others
	Dihydrofluorescein diacetate (Diacetyldihydrofluorescein) is a fluorescent probe for measuring oxidative stress in cell-free systems and cellular models.		Others
T21899	Misonidazole	SR-1354,SR1354,Ro 7-0582	GPX
	Misonidazole as a novel GPX inhibitors to cause oxidative stress in chemotherapy-resistant tumors.		GPX
T13436	(E)-[6]-Dehydroparadol	(6)-Dehydroparadol	Nrf2
	(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.		Nrf2
T5913	Sulbutiamine	Bisibuthiamine	Antioxidant
	Sulbutiamine (Bisibuthiamine) is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.		Antioxidant
T20318	Benzylideneaniline	N-Benzylideneaniline	Others
	Benzylideneaniline (N-Benzylideneaniline) is a potent inhibitor of xyloglucan-α,β-dioxygenase, a key enzyme in the oxidative cleavage of the central double bond of xyloglucan.		Others
T12059L	Mitoquinone mesylate	MitoQ mesylate,MitoQ10 mesylate	Reactive Oxygen Species
			Reactive Oxygen Species
T34076	Piprozolin	W3699,W-3699,W 3699
	Piprozolin (W 3699) is a new type of choleretic acid that shows slight analgesic properties at high doses during chronic experiments.Piprozolin has a slight induction of certain enzymes of the oxidative system.
T15373	Gboxin		ATPase , Mitochondrial Metabolism
	Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.		ATPase , Mitochondrial Metabolism
T12019	Methylproamine		Others
	Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.		Others
T1710	Trolox		Apoptosis , Antioxidant , Ferroptosis , Reactive Oxygen Species
	Trolox is a vitamin E analogue, used in reducing oxidative stress or damage.
T6834	FCCP	Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone	ATPase , Mitochondrial Metabolism
	FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. FCCP is often used as an apoptosis inducer.		ATPase , Mitochondrial Metabolism
T5837	Tamerit		Others
	Tamerit as an efficient inhibitor of oxidative burst in monocytes.		Others
T27303	Farglitazar	GI-262570,GI-2570,GW 262570X,GI 262570,GI262570	PPAR
	Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer that inhibits stellate cell activation by activating receptor γ via oxidative enzymes proliferators and is used in the study of diabetes.		PPAR

Compounds

Iprodione

T5116

Synonym:

Target: Others, Reactive Oxygen Species, Antifungal

Synonym: Phenazone,Phenazon

Target: Potassium Channel

Target: OXPHOS, Mitochondrial Metabolism, Autophagy

Rafoxanide

T7093

Synonym:

Target: CDK, Parasite

Synonym: 4-phenyl-2- propionamidotetralin

Target: Melatonin Receptor, MT Receptor

BI-6C9

T5827

Synonym:

Target: Apoptosis, Others, Mitochondrial Metabolism

Tolcapone

T6708

Synonym: Tasmar,Ro 40-7592

Target: Apoptosis, Beta Amyloid, Transferase

Idebenone

T0412

Synonym: CV-2619

Target: Apoptosis, Antioxidant, Mitochondrial Metabolism

Mito-LND

T9211

Synonym: Mito-Loidamine

Target: OXPHOS, Reactive Oxygen Species, Mitochondrial Metabolism, Autophagy

YM-750

T23550

Synonym: YM 750

Target: Acyltransferase

Saralasin acetate(34273-10-4 free base)

Synonym: 2'-Deoxyguanosine-5'-triphosphate

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

IACS-010759

T5337

Synonym: IACS-10759,IACS 10759,IACS10759

Target: Apoptosis, Others, Mitochondrial Metabolism

L-BUTHIONINE-(S,R)-SULFOXIMINE

T5371

Synonym: L-Butionine sulfoximine

Target: Others, Ferroptosis

Boc-Asp(OMe)-fluoromethyl ketone

T39308

Synonym: Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK

Target: Caspase

Terlipressin Acetate

T13920L

Synonym: Terlipressin diacetate anhydrous,Terlipressin acetate anhydrous

Target: Vasopressin Receptor

Target: Apoptosis, HSP, Reactive Oxygen Species

Binodenoson

T9516

Synonym: WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos

Target: Adenosine Receptor

2,5-Dimethyl-3(2H)-furanone

T22309

Synonym: 2,5-Dimethyl-2,3-dihydrofuran-3-one

Target: Others

Fluvastatin sodium

T1487

Synonym: XU 62320 sodium,XU-62-320,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

2',7'-Dichlorofluorescein diacetate

T20684

Synonym: Diacetyldichlorofluorescein,Leuco-dcf diacetate,Dcfh-DA,DCFDA

Target: Others

IMT1B

T8842

Synonym: 3-Piperidinecarboxylic acid, 1-[(2R)-2-[[4-(2-chloro-4-fluorophenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-1-oxopropyl]-, (3S)-,LDC203974

Target: Others, DNA/RNA Synthesis

Celiprolol hydrochloride

T1244

Synonym: Selecor,Selectrol

Target: Adrenergic Receptor

Synonym: R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401

Target: Apoptosis, Reactive Oxygen Species

Fructosylvaline

T25441

Synonym: Fru-val,N-Fructosyl Valine

Target: Others

Dihydrofluorescein diacetate

T18976

Synonym: Diacetyldihydrofluorescein

Target: Others

Misonidazole

T21899

Synonym: SR-1354,SR1354,Ro 7-0582

Target: GPX

(E)-[6]-Dehydroparadol

T13436

Synonym: (6)-Dehydroparadol

Target: Nrf2

Sulbutiamine

T5913

Synonym: Bisibuthiamine

Target: Antioxidant

Benzylideneaniline

T20318

Synonym: N-Benzylideneaniline

Target: Others

Mitoquinone mesylate

T12059L

Synonym: MitoQ mesylate,MitoQ10 mesylate

Target: Reactive Oxygen Species

Piprozolin

T34076

Synonym: W3699,W-3699,W 3699

Target: ATPase, Mitochondrial Metabolism

Target: Apoptosis, Antioxidant, Ferroptosis, Reactive Oxygen Species

FCCP

T6834

Synonym: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone

Target: ATPase, Mitochondrial Metabolism

Synonym: GI-262570,GI-2570,GW 262570X,GI 262570,GI262570

Target: PPAR

カタログ番号	製品名	別名	ターゲット
T2738	Dehydroandrographolide		NOS , Influenza Virus
	Dehydroandrographolide is a natural compound extracted from herbal medicine Andrographis paniculata (Burm f) Nees.		NOS , Influenza Virus
TC0039	Vasicinone		Others
	Vasicinone may act as a hepatoprotective agent. (±)-Vasicinone has significant antitussive, expectorant, and bronchodilating activities, which can be used to treat respiratory disease.(S)-Vasicinone exhibits antiprolifer...		Others
T2S1720	Huperzine B		AChE
	1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.		AChE
T7982	3,6-Dihydroxyflavone		Others
	3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.		Others
T5783	Rosamultin		Antioxidant , HIV Protease
	Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity.		Antioxidant , HIV Protease
T13795	Nicotinamide riboside		Sirtuin
	Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.		Sirtuin
T8678	Naphthazarin	5,8-Dihydroxy-1,4-naphthoquinone,DHNQ	Apoptosis
	Naphthazarin (5,8-Dihydroxy-1,4-naphthoquinone) is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, inter...		Apoptosis
T41358	2-Hydroxybenzylamine		Others
	2-Hydroxybenzylamine, a potent small molecule scavenger of IsoLGs, sequesters the reactive species as inert adducts. 2-Hydroxybenzylamine may be used to decrease early recurrence of atrial fibrillation and other atrial a...		Others
TN1039	Tamarixetin	4'-O-Methyl Quercetin	Endogenous Metabolite , Immunology/Inflammation related
	Tamarixetin (4'-O-Methyl Quercetin) (4'-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-inflammatory and anti-oxidative effects. Tamarixetin protects against cardiac hypertrophy.		Endogenous Metabolite , Immunology/Inflammation related
T3394	Timosaponin BII	Prototimosaponin A III	Beta Amyloid , Others , BACE
	Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the...		Beta Amyloid , Others , BACE
TN2100	Pratensein		Others , NF-κB
	Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.		Others , NF-κB
T3S1265	Liriopesides B	Nolinospiroside F	Others
	Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells.		Others
TN2244	Sulfuretin		NF-κB , Autophagy
	Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 thr...		NF-κB , Autophagy
T5669	Citric acid monohydrate		Others
	Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients a...		Others
T5S0636	Citric acid	Citro,Citretten	Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
	1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
TN1926	Methyl caffeate	Methyl caffeate acid	Others , Antibacterial
	Methyl caffeate (Methyl caffeate acid) acid		Others , Antibacterial
T2800	L-Theanine		Apoptosis , Others
	L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.		Apoptosis , Others
T3S1319	(+)-Magnoflorine	Escholin,Magnoflorine,Thalictrin,Escholine	Others , Antifungal
	(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech...		Others , Antifungal
T10148	4-Hydroxynonenal	4-HNE	Dehydrogenase , Endogenous Metabolite
	4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).		Dehydrogenase , Endogenous Metabolite
TJO2742	DL-Methionine	methionine,Acimetion,Racemethionine	Parasite
	DL-Methionine (Acimetion) is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. DL-Methionine is found in meat, fish, and dairy products. It plays an important role in the many funct...		Parasite
T2230	Paeoniflorin	Peoniflorin	HSP , COX
	Paeoniflorin (Peoniflorin) is a herbal constituent extracted from the root of Paeonia albiflora Pall.		HSP , COX
T6220	Nicotinamide riboside chloride		Sirtuin , Endogenous Metabolite
	Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.		Sirtuin , Endogenous Metabolite
T0626	Uric Acid	2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate	Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase
	Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ...
T20793	Magnesium Lithospermate B	Monomethyl lithospermate B,Lithospermate B	Others
	Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...		Others
TN6339	(R)-5-Hydroxy-1,7-diphenylheptan-3-one	(5R)-Dihydroyashabushiketol	Others
	(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) is extracted from the rhizomes of Alpinia officinarum, a Chinese medicinal herb. (R)-5-Hydroxy-1,7-diphenylheptan-3-one inhibits melanogenesis in theop...		Others
T7917	4'-Hydroxychalcone	2-Benzal-4-Hydroxyacetophenone	Proteasome
	4'-Hydroxychalcone (2-Benzal-4-Hydroxyacetophenone) is a chalcone metabolite with hepatoprotective activity		Proteasome
T2198	Arecoline hydrobromide	Arecoline HBr,Arecoline bromide	AChR
	Arecoline hydrobromide (Arecoline HBr) is a muscarinic acetylcholine receptor agonist.		AChR
T3S1068	Oxyresveratrol	trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene	Tyrosinase , Autophagy , HSV
	1. Oxyresveratro can inhibit tyrosinase activity. 2. Oxyresveratro is useful to trauma models, as toxicity to glia could be beneficial by inhibiting reactive gliosis. 3. Oxyresveratrol (trans-Oxyresveratrol) has antioxid...		Tyrosinase , Autophagy , HSV
T3S1320	(+)-Magnoflorine iodide	Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide	Others , Antifungal
	(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.		Others , Antifungal
T3982	Vulpinic Acid	Vulpic acid,Pulvinic acid methyl ester	Others
	Vulpinic Acid (Pulvinic acid methyl ester) is a lichen metabolite with anti-inflammatory, antibacteria, properties, plant growth inhibitor.		Others
T6S0117	Avicularin	Fenicularin	ERK
	Avicularin (Fenicularin) has anti-allergic, anti-inflammatory, hepatoprotective, antioxidant, anti-tumor and other activities. It ameliorates human hepatocellular carcinoma by modulating the activities of NF-κB(p65), COX...		ERK
T4S1321	(+)-Magnoflorine chloride	Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride	Others , Antifungal
	(+)-Magnoflorine chloride (Escholine chloride) has anti-inflammatory activity, it can inhibit inflammations.		Others , Antifungal
T8193	α-Thujone	Thujone,ALPHA-(-)-THUJONE	Apoptosis , Reactive Oxygen Species , GABA Receptor , AChR , Parasite , Autophagy
	α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.
T2870	Matrine	Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine	Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
	Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.		Mitophagy , Ferroptosis , Opioid Receptor , Autophagy
T9454	4-Hydroxyestrone		Estrogen Receptor/ERR , Endogenous Metabolite
	4-Hydroxyestrone, an endogenous estrogen metabolite, can strongly protect neuronal cells against oxidative damage.		Estrogen Receptor/ERR , Endogenous Metabolite
T37710	5-Hydroxyoxindole		Reactive Oxygen Species
	5-Hydroxyoxindole has been identified as a urinary metabolite of indole, which is produced from tryptophane via the tryptophanase activity of gut bacteria [1]. 5-Hydroxyoxindole has lipid peroxidation inhibition activit...		Reactive Oxygen Species
TN6909	Polyporusterone B	(1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one	Others
	Polyporusterone B ((1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one) is a triterpene carboxylic aci...		Others
T20597	Alginic acid	Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine	Apoptosis , Autophagy , Histamine Receptor
	Alginic acid (Snow acid algin G) is a natural polysaccharide extracted from brown seaweeds with anti-anaphylactic and anti-inflammatory activities. Alginic acid inhibits histamine release and can be used in the food indu...		Apoptosis , Autophagy , Histamine Receptor
TN6924	Anhydrosafflor yellow B	(2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB	Others
	Anhydrosafflor yellow B ((2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,...		Others
TN1461	(-)-Butin	Butin	Akt , PI3K , Nrf2
	(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SO...		Akt , PI3K , Nrf2
TN1600	Eclalbasaponin I		Others
	Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w...		Others
T2S2003	Phlorizin dihydrate	Phloridzin dihydrate	Others
	1. Phlorizin dihydrate (Phloridzin dihydrate) can significantly inhibit oxidative DNA damage.		Others
T8177	Galactinol		Others
	Galactinol Hydrate scavenges hydroxyl free radicals and protects plant cells from oxidative damage.		Others
T6S1966	Curculigoside	Curculigoside A	Antioxidant , NF-κB , JAK , STAT
	1. Curculigoside (Curculigoside A) can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disord...		Antioxidant , NF-κB , JAK , STAT
T2S2172	Nerolidol	(±)-Nerolidol,Peruviol	Others , Endogenous Metabolite , Antibacterial , Parasite , Antifungal
	Nerolidol (Peruviol) shows sedative effects in animals, oxidative process plays a crucial role on neuronal pathological consequence. Nerolidol is mainly related to ROS and DNA single strand breaks generated by the presen...
T8704	4-hydroxyphenyl acetate		Nrf2
	4-Acetoxyphenol Prevents RPE Oxidative Stress-Induced Necrosis by Functioning as an NRF2 Stabilizer		Nrf2
T19165	8-Hydroxyguanine	8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine	Endogenous Metabolite
	8-Hydroxyguanine (8 Hydroxyguanine) is the major premutagenic damage produced by reactive oxygen species. It causes G-T and A-C substitutions.8-Hydroxyguanine is a biomarker for RNA oxidation and oxidative DNA damage.8-H...		Endogenous Metabolite
T6S1768	Narcissin	Isorhamnetin 3-Rutinoside,Narcissoside	Antioxidant
	Narcissin (Isorhamnetin 3-Rutinoside), with synergism of B.flavum flavonoid and rutin, could be responsible for stronger protection against mitochondrial induced oxidative stress.		Antioxidant
T2805	Chlorogenic Acid	NSC-407296,3-O-Caffeoylquinic acid,Heriguard	Others , Influenza Virus , Reactive Oxygen Species , HIF/HIF Prolyl-Hydroxylase , Endogenous Metabolite , Antibacterial
	Chlorogenic Acid (NSC-407296) is a naturally occurring phenolic acid which is a carcinogenic inhibitor. It has also been shown to prevent paraquat-induced oxidative stress in rats.
T19418	Methionine sulfoxide		Endogenous Metabolite
	Methionine sulfoxide, an oxidation product of methionine formed through interaction with reactive oxygen species, serves as a biomarker for oxidative stress in vivo.		Endogenous Metabolite
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天然物製品

Dehydroandrographolide

T2738

Synonym:

Target: NOS, Influenza Virus

Target: Antioxidant, HIV Protease

Nicotinamide riboside

Synonym: 5,8-Dihydroxy-1,4-naphthoquinone,DHNQ

Synonym: 4'-O-Methyl Quercetin

Target: Endogenous Metabolite, Immunology/Inflammation related

Timosaponin BII

T3394

Synonym: Prototimosaponin A III

Target: Beta Amyloid, Others, BACE

Pratensein

TN2100

Synonym:

Target: Others, NF-κB

Liriopesides B

T3S1265

Synonym: Nolinospiroside F

Target: NF-κB, Autophagy

Citric acid monohydrate

Synonym: Citro,Citretten

Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic

Methyl caffeate

TN1926

Synonym: Methyl caffeate acid

Target: Others, Antibacterial

L-Theanine

T2800

Synonym:

Target: Apoptosis, Others

(+)-Magnoflorine

T3S1319

Synonym: Escholin,Magnoflorine,Thalictrin,Escholine

Target: Others, Antifungal

4-Hydroxynonenal

T10148

Synonym: 4-HNE

Target: Dehydrogenase, Endogenous Metabolite

DL-Methionine

TJO2742

Synonym: methionine,Acimetion,Racemethionine

Nicotinamide riboside chloride

T6220

Synonym:

Target: Sirtuin, Endogenous Metabolite

Uric Acid

T0626

Synonym: 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase

Magnesium Lithospermate B

T20793

Synonym: Monomethyl lithospermate B,Lithospermate B

Target: Others

(R)-5-Hydroxy-1,7-diphenylheptan-3-one

TN6339

Synonym: (5R)-Dihydroyashabushiketol

Target: Others

4'-Hydroxychalcone

T7917

Synonym: 2-Benzal-4-Hydroxyacetophenone

Target: Proteasome

Arecoline hydrobromide

T2198

Synonym: Arecoline HBr,Arecoline bromide

Target: AChR

Oxyresveratrol

T3S1068

Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,Tetrahydroxystilbene

Target: Tyrosinase, Autophagy, HSV

(+)-Magnoflorine iodide

T3S1320

Synonym: Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide

Target: Others, Antifungal

Vulpinic Acid

T3982

Synonym: Vulpic acid,Pulvinic acid methyl ester

(+)-Magnoflorine chloride

T4S1321

Synonym: Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride

Target: Others, Antifungal

α-Thujone

T8193

Synonym: Thujone,ALPHA-(-)-THUJONE

Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, AChR, Parasite, Autophagy

Matrine

T2870

Synonym: Vegard,Matridin-15-one,Matrinium,α-Matrine,(+)-Matrine

Target: Mitophagy, Ferroptosis, Opioid Receptor, Autophagy

4-Hydroxyestrone

T9454

Synonym:

Target: Estrogen Receptor/ERR, Endogenous Metabolite

5-Hydroxyoxindole

T37710

Synonym:

Target: Reactive Oxygen Species

Polyporusterone B

TN6909

Synonym: (1R,2R,4S,5R,7R,11R,14S,15R)-14-[(2R,3R)-2,3-dihydroxy-6-methyl-5-methylideneheptan-2-yl]-4,5,11-trihydroxy-2,15-dimethyltetracyclo[8.7.0.02,?.011,1?]heptadec-9-en-8-one

Target: Others

Alginic acid

T20597

Synonym: Protanal LF,Snow acid algin G,Kelacid,Sazzio,Norgine

Target: Apoptosis, Autophagy, Histamine Receptor

Anhydrosafflor yellow B

TN6924

Synonym: (2S,3S)-6,7-dihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-2-[(1S,2R,3R)-1,2,3,4-tetrahydroxybutyl]-3-{2,3,4-trihydroxy-5-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]-6-oxo-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]cyclohexa-1,4-dien-1,AHSYB

Target: Akt, PI3K, Nrf2

Synonym: Phloridzin dihydrate

Synonym: Curculigoside A

Target: Antioxidant, NF-κB, JAK, STAT

nerolidol

T2S2172

Synonym: (±)-Nerolidol,Peruviol

Target: Others, Endogenous Metabolite, Antibacterial, Parasite, Antifungal

4-hydroxyphenyl acetate

Synonym: 8 Hydroxyguanine,7,8-dihydro-8-oxoguanine,2-Amino-6,8-dihydroxypurine

Target: Endogenous Metabolite

Narcissin

T6S1768

Synonym: Isorhamnetin 3-Rutinoside,Narcissoside

Target: Antioxidant

Chlorogenic Acid

T2805

Synonym: NSC-407296,3-O-Caffeoylquinic acid,Heriguard

Target: Others, Influenza Virus, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Antibacterial

Methionine sulfoxide

T19418

Synonym:

Target: Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04460	OXSR1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environme...
TMPH-00359	AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)	Caulobacter vibrioides	E. coli
	AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is B8GWW6.
TMPH-00577	AlkB Protein, E. coli, Recombinant (His & Myc & SUMO)	E. coli	E. coli
	AlkB Protein, E. coli, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 44.1 kDa and the accession number is P05050.
TMPY-00541	LON PROTEASE Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura...
TMPH-02681	GPX7 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. G...
TMPH-01397	LANCL1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Functions as glutathione transferase. Catalyzes conjugation of the glutathione (GSH) to artificial substrates 1-chloro-2,4-dinitrobenzene (CDNB) and p-nitrophenyl acetate. Mitigates neuronal oxidative stress during norma...
TMPH-03654	Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)	VACV	E. coli
	Catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal...
TMPY-02299	ALDH3A1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (...
TMPY-02043	PARK7/DJ-1 Protein, Human, Recombinant (His)	Human	E. coli
	Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress....
TMPH-03275	Cytoglobin Protein, Rat, Recombinant (His & Myc)	Rat	E. coli
	May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity.
TMPH-01296	GPX5 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective syste...
TMPH-02863	LOX Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus Insect Cells
	Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in t...
TMPH-00641	YTFE Protein, E. coli, Recombinant (GST)	E. coli	E. coli
	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions. YTFE Protein, E. coli, Recombinant (GST) is expressed in E. coli expression system with N-...
TMPK-00077	EPO/Erythropoietin Protein, Human, Recombinant	Human	HEK293 Cells
	Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition im...
TMPH-03054	Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)	Neosartorya fumigata	E. coli
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPH-00794	Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)	Helicobacter pylori	E. coli
	Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical produ...
TMPY-04073	MRPL44 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	MRPL44 (Mitochondrial Ribosomal Protein L44) is a Protein Coding gene. MRPL44 encodes a protein in the large subunit of the mitochondrial ribosome and is suggested to locate near the tunnel exit of the yeast mitochondria...
TMPH-03443	GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the pres...
TMPH-00773	RuBisCO large subunit Protein, Glycine max, Recombinant (His & SUMO)	Glycine max	E. coli
	RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration pro...
TMPH-02102	PON1 Protein, Human, Recombinant (GST)	Human	E. coli
	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediate...
TMPH-03721	IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His)	Yersinia pestis	E. coli
	Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the Ibp...
TMPH-03359	LOX Protein, Rat, Recombinant (His)	Rat	E. coli
	Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in t...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His)	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPH-02903	PON1 Protein, Mouse, Recombinant	Mouse	E. coli
	Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediate...
TMPH-02875	ROMO1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.; Induces production of reactive oxygen species (ROS) which are n...
TMPH-01553	GBP2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to aut...
TMPJ-00720	TXNDC12 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defens...
TMPH-02153	Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduct...
TMPH-01969	LOX Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in t...
TMPH-00072	2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	P. pastoris (Yeast)
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPJ-00982	DHS Protein, Human, Recombinant (His)	Human	E. coli
	Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to...
TMPH-02104	Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may al...
TMPJ-00380	AOC3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases i...
TMPJ-01076	FKBP4 Protein, Human, Recombinant (His)	Human	E. coli
	FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone recepto...
TMPH-02199	TXNRD2 Protein, Human, Recombinant (His)	Human	E. coli
	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxide...
TMPH-02618	CYP2E1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electr...
TMPY-02544	FANCA Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	FANCA is one of the six known Fanconi anemia gene products (FANCA, FANCC, FANCD2, FANCE, FANCF, and FANCG proteins). Fanconi anemia (FA) is a genetic disorder predisposing to aplastic anemia and cancer characterized by h...
TMPY-01770	HAO1 Protein, Human, Recombinant (His)	Human	E. coli
	Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2...
TMPH-00916	ADH1B Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the NAD-dependent oxidation of all-trans-retinol and its derivatives such as all-trans-4-hydroxyretinol and may participate in retinoid metabolism. In vitro can also catalyzes the NADH-dependent reduction of al...
TMPJ-00105	SOD2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic super...
TMPY-02890	ERP27 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	ERP27 contains 1 thioredoxin domain and is a noncatalytic member of the protein disulfide isomerase family. Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide...
TMPY-02201	Peroxiredoxin 6 Protein, Human, Recombinant (His)	Human	E. coli
	PRDX6, a member of antioxidant protein superfamily, plays an important role in oxidative stress, catabolism of lipids and phospholipid lipisomes. Peroxiredoxin 6 (PRDX6) is involved in redox regulation of the cell and is...
TMPJ-00379	AOC3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycop...
TMPH-01428	TRAP1 Protein, Human, Recombinant (GST)	Human	E. coli
	Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to ...
TMPH-02661	Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPY-02271	TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)	Human	E. coli
	Thioredoxin reductase 1 (TXNRD1) which is a selenocysteine-containing protein is overexpressed in many malignancies. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells against oxidat...
TMPK-00693	HSP27/HSPB1 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against oxidative stress. This protein is expressed only in insulin-d...
TMPJ-00934	PRDX3 Protein, Human, Recombinant	Human	E. coli
	Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and hu...
TMPH-02660	Frataxin/FXN Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Promotes the biosynthesis of heme and assembly and repair of iron-sulfur clusters by delivering Fe(2+) to proteins involved in these pathways. May play a role in the protection against iron-catalyzed oxidative stress thr...
TMPK-01168	LOX-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	LOX-1 is a transmembrane glycoprotein that binds to and internalizes ox-LDL.LOX-1 gene deletion in mice and anti-LOX-1 therapy has been shown to decrease inflammation, oxidative stress and atherosclerosis. LOX-1 deletion...
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OXSR1 Protein, Human, Recombinant (GST)

TMPY-04460

Species: Human

Expression System: Baculovirus Insect Cells

AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)

TMPH-00359

Species: Caulobacter vibrioides

Expression System: E. coli

AlkB Protein, E. coli, Recombinant (His & Myc & SUMO)

TMPH-00577

Species: E. coli

Expression System: E. coli

LON PROTEASE Protein, E. coli, Recombinant (His)

TMPY-00541

Species: E. coli

Expression System: E. coli

GPX7 Protein, Mouse, Recombinant (His & Myc)

TMPH-02681

Species: Mouse

Expression System: E. coli

LANCL1 Protein, Human, Recombinant (His & Myc)

TMPH-01397

Species: Human

Expression System: E. coli

Vaccinia virus (strain Western Reserve) 3-beta-HSD Protein (His & Myc)

TMPH-03654

Species: VACV

Expression System: E. coli

ALDH3A1 Protein, Human, Recombinant (His)

TMPY-02299

Species: Human

Expression System: Baculovirus Insect Cells

PARK7/DJ-1 Protein, Human, Recombinant (His)

TMPY-02043

Species: Human

Expression System: E. coli

Cytoglobin Protein, Rat, Recombinant (His & Myc)

TMPH-03275

Species: Rat

Expression System: E. coli

GPX5 Protein, Human, Recombinant (GST & His)

TMPH-01296

Species: Human

Expression System: E. coli

LOX Protein, Mouse, Recombinant (His & Myc)

TMPH-02863

Species: Mouse

Expression System: Baculovirus Insect Cells

YTFE Protein, E. coli, Recombinant (GST)

TMPH-00641

Species: E. coli

Expression System: E. coli

EPO/Erythropoietin Protein, Human, Recombinant

TMPK-00077

Species: Human

Expression System: HEK293 Cells

Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)

TMPH-03054

Species: Neosartorya fumigata

Expression System: E. coli

Dps Protein, Helicobacter pylori, Recombinant (His & SUMO)

TMPH-00794

Species: Helicobacter pylori

Expression System: E. coli

MRPL44 Protein, Human, Recombinant (His)

TMPY-04073

Species: Human

Expression System: Baculovirus Insect Cells

GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)

TMPH-03443

Species: Saccharomyces cerevisiae

Expression System: E. coli

RuBisCO large subunit Protein, Glycine max, Recombinant (His & SUMO)

TMPH-00773

Species: Glycine max

Expression System: E. coli

PON1 Protein, Human, Recombinant (GST)

TMPH-02102

Species: Human

Expression System: E. coli

IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His)

TMPH-03721

Species: Yersinia pestis

Expression System: E. coli

LOX Protein, Rat, Recombinant (His)

TMPH-03359

Species: Rat

Expression System: E. coli

Cytoglobin/CYGB Protein, Human, Recombinant (His)

TMPJ-01248

Species: Human

Expression System: E. coli

PON1 Protein, Mouse, Recombinant

TMPH-02903

Species: Mouse

Expression System: E. coli

ROMO1 Protein, Mouse, Recombinant (His)

TMPH-02875

Species: Mouse

Expression System: E. coli

GBP2 Protein, Human, Recombinant (E. coli, His)

TMPH-01553

Species: Human

Expression System: E. coli

TXNDC12 Protein, Human, Recombinant (His)

TMPJ-00720

Species: Human

Expression System: HEK293 Cells

Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)

TMPH-02153

Species: Human

Expression System: E. coli

LOX Protein, Human, Recombinant (His & Myc & SUMO)

TMPH-01969

Species: Human

Expression System: E. coli

2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)

TMPH-00072

Species: Arabidopsis thaliana

Expression System: P. pastoris (Yeast)

DHS Protein, Human, Recombinant (His)

TMPJ-00982

Species: Human

Expression System: E. coli

Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)

TMPH-02104

Species: Human

Expression System: E. coli

AOC3 Protein, Human, Recombinant (His)

TMPJ-00380

Species: Human

Expression System: HEK293 Cells

FKBP4 Protein, Human, Recombinant (His)

TMPJ-01076

Species: Human

Expression System: E. coli

TXNRD2 Protein, Human, Recombinant (His)

TMPH-02199

Species: Human

Expression System: E. coli

CYP2E1 Protein, Mouse, Recombinant (His)

TMPH-02618

Species: Mouse

Expression System: E. coli

FANCA Protein, Human, Recombinant (His)

TMPY-02544

Species: Human

Expression System: Baculovirus Insect Cells

HAO1 Protein, Human, Recombinant (His)

TMPY-01770

Species: Human

Expression System: E. coli

ADH1B Protein, Human, Recombinant (His & SUMO)

TMPH-00916

Species: Human

Expression System: E. coli

SOD2 Protein, Human, Recombinant (His)

TMPJ-00105

Species: Human

Expression System: HEK293 Cells

ERP27 Protein, Human, Recombinant (mFc)

TMPY-02890

Species: Human

Expression System: HEK293 Cells

Peroxiredoxin 6 Protein, Human, Recombinant (His)

TMPY-02201

Species: Human

Expression System: E. coli

AOC3 Protein, Human, Recombinant (hFc)

TMPJ-00379

Species: Human

Expression System: HEK293 Cells

TRAP1 Protein, Human, Recombinant (GST)

TMPH-01428

Species: Human

Expression System: E. coli

Frataxin/FXN Protein, Mouse, Recombinant (E. coli, His)

TMPH-02661

Species: Mouse

Expression System: E. coli

TRXR1/TXNRD1 Protein, Human, Recombinant (aa 161-647, His)

TMPY-02271

Species: Human

Expression System: E. coli

HSP27/HSPB1 Protein, Human, Recombinant (His)

TMPK-00693

Species: Human

Expression System: E. coli

PRDX3 Protein, Human, Recombinant

TMPJ-00934

Species: Human

Expression System: E. coli

Frataxin/FXN Protein, Mouse, Recombinant (His)

TMPH-02660

Species: Mouse

Expression System: P. pastoris (Yeast)

LOX-1 Protein, Mouse, Recombinant (His)

TMPK-01168

Species: Mouse

Expression System: HEK293 Cells

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カタログ番号	製品名
L2910	Antioxidant Compound Library	1314 compounds
	Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. ...
L5300	Mitochondria-Targeted Compound Library	812 compounds
	A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L6110	Alkaloid Natural Product Library	464 compounds
	A unique collection of 464 natural alkaloids can be used for high throughput and high content screening；
L6140	Saccharide and Glycoside Natural Product Library	362 compounds
	A unique collection of 362 saccharides and glycosides compounds can be used for HTS and HCS；
L2520	Glycometabolism Compound Library	702 compounds
	702 glycometabolism-related comounds, can be used for HTS and HCT;
L6120	Flavonoid Natural Product Library	514 compounds
	A unique collection of 514 flavonoids can be used for high throughput and high content screening；
L9840	Anti-Alzheimer's Disease Compound Library	986 compounds
	A unique collection of 986 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.