Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).
説明 | 1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM). |
ターゲット&IC50 | CYP1A1:0.18 μM, CYP1A2:0.32 μM, CYP2B1:0.04 μM |
In vitro | The Ki values of 1-Ethynylpyrene against P450 1A2, and 2B1 is 0.32 and 0.04 μM, respectively[1]. |
分子量 | 226.27 |
分子式 | C18H10 |
CAS No. | 34993-56-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9.09 mg/mL (40.17 mM)
You can also refer to dose conversion for different animals. 詳細
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1-Ethynylpyrene 34993-56-1 Metabolism P450 1A1 1 Ethynylpyrene 2B1 Inhibitor CYPs Cytochrome P450 1Ethynylpyrene inhibit 1A2 cytochromes inhibitor