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ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T9704	1-Ethynylpyrene		P450
	1-Ethynylpyrene is an aryl acetylenic inhibitor of CYTP450 1A1(IC50=0.18 μM), 1A2(IC50 = 0.32 μM), and 2B1(IC50 = 0.04 μM).		P450
T22774L	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) is Elongation factor 1 subunit.eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha sub...		Others
T27109	CYP1A1 inhibitor 8a
	CYP1A1 inhibitor 8a is a potent and selective CYP1A1 inhibitor. It antagonizes B[a]P mediated activation of aromatic hydrocarbon receptor (AhR) in yeast cells, thereby protects human cells from CYP1A1-mediated B[a]P toxi...
T22774	Eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]		Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. ...		Others
T63341	ALDH1A1-IN-2		Dehydrogenase
	ALDH1A1-IN-2 is a potent aldehyde dehydrogenase 1a1 (aldh1a1) inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity.		Dehydrogenase
T64228	ALDH1A1-IN-3
	ALDH1A1-IN-3 is a good and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50: μM).ALDH1A1-IN-3 is effective in improving glucose consumption in HepG2 cells.ALDH1A1-IN-3 can be used for studies to improve ...
T78204	CYP11A1-IN-1
	CYP11A1-IN-1 (compound 30) is a selective inhibitor of the enzyme CYP11A1, displaying an IC50 ranging from 201-2000 nM. It is applicable in the study of steroid receptor-mediated diseases, specifically targeting the andr...
T61287	CYP121A1-IN-1
	CYP121A1-IN-1 is a potent inhibitor of CYP121A1, demonstrating favorable activity against Mycobacterium tuberculosis (H37Rv MIC 90 ~6.25 μM, ~2.2 μg/mL). It significantly reduces mycocyclosin production by blocking the C...
T23903	CM037	CM-037,A-37,CM 037,A37,A 37	Dehydrogenase
	CM037 (A-37) is a selective ALDH1A1 (acetaldehyde dehydrogenase 1A1) inhibitor (IC50; 4.6 µM) with antitumor activity and may be used in studies to eliminate gynecologic malignancies.		Dehydrogenase
T6903	NCT-501	NCT501	Dehydrogenase
	NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.		Dehydrogenase
T12197	NCT-506		Others
	NCT-506 is an orally bioavailable inhibitors of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50 of 7 nM).		Others
T23901	CM026	CM 026,CM-026
	CM026 is a selective aldehyde dehydrogenase 1A1 inhibitor that acts by binding within the aldehyde binding pocket of ALDH1A1 in an uncompetitive partial mode of inhibition.
T19685	Faldaprevir	BI-201335,BI201335,BI 201335
	Faldaprevir is an effective NS3/NS4A protease inhibitor potentially for the treatment of HCV infection. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1.
T24988	7ETMC	7 ETMC,7-ETMC
	7ETMC is a selective Human Cytochrome P450s 1A1 and 1A2 inhibitor. 7ETMC showed IC50s of 0.46 μM and 0.50 μM for P450s 1A1 and 1A2 in the first six minutes, respectively, and did not show any inhibition activity for P450...
T71215	Faldaprevir sodium
	Faldaprevir sodium is a potent NS3/NS4A protease inhibitor potentially for the treatment of HCV infection. Faldaprevir is known to inhibit P-glycoprotein, CYP3A4, and UDP-glucuronosyltransferase 1A1.
T62328	Cabotegravir sodium
	Cabotegravir sodium is a potent inhibitor of HIV integrase and is able to act on HIVADA (IC50: 2.5 nM). cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1 and is less li...
T39485	NCT-501 hydrochloride
	NCT-501 hydrochloride is a highly potent and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), which is based on theophylline. It effectively inhibits hALDH1A1 with an IC50 value of 40 nM, exhibiting superior ...
T70313	Indoxyl Sulfate-d5 potassium salt
	Indoxyl sulfate-d5 is intended for use as an internal standard for the quantification of indoxyl sulfate by GC- or LC-MS. Indoxyl sulfate is a uremic toxin and a metabolite of tryptophan. It is formed via sulfation of in...

Compounds

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]

Target: Dehydrogenase

Synonym: CM-037,A-37,CM 037,A37,A 37

Target: Dehydrogenase

NCT-501

T6903

Synonym: NCT501

Target: Dehydrogenase

Synonym: CM 026,CM-026

Target:

Faldaprevir

T19685

Synonym: BI-201335,BI201335,BI 201335

Target:

7ETMC

T24988

Synonym: 7 ETMC,7-ETMC

NCT-501 hydrochloride

T39485

Synonym:

Target:

Indoxyl Sulfate-d5 potassium salt

T70313

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T8038	7-Ethoxy-4-Methylcoumarin		Others
	7-Ethoxy-4-Methylcoumarin is considered an inhibitor of enzymes in cells and has been used in studies of enzyme inhibition and has been used to study the effects of various drugs on the human body.		Others
T4109	Rhapontigenin 3'-O-glucoside		Others
	Rhapontigenin 3'-O-glucoside, a derivative of Rhapontigenin, functions as a P450 1A1 inhibitor and is utilized in cancer prevention.		Others
T3776	Rhapontigenin	Protigenin	P450 , Antibacterial , Antifungal
	Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. R...		P450 , Antibacterial , Antifungal
T0671	2-Naphthol	Betanaphthol	Others , Endogenous Metabolite
	2-Naphthol (Betanaphthol) is an isomer of 1-naphthol, differing by the location of the hydroxyl group on the naphthalene ring.		Others , Endogenous Metabolite
T4S0145	Corylifol A	Corylinin	hCE , STAT , UGT
	1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia...		hCE , STAT , UGT
T82305	Glucoarabin
	Glucoarabin, a bioactive glucosinolate, upregulates the phase II detoxification enzyme quinone reductase (NQO1) in Hepa1c1c7 cells when hydrolyzed (hGSL 9), without affecting cytochrome P450 (CYP) 1A1 activity [1].

天然物製品

7-Ethoxy-4-Methylcoumarin

T8038

Synonym:

Target: Others

Rhapontigenin 3'-O-glucoside

Target: P450, Antibacterial, Antifungal

2-Naphthol

T0671

Synonym: Betanaphthol

Target: Others, Endogenous Metabolite

Corylifol A

T4S0145

Synonym: Corylinin

Target: hCE, STAT, UGT

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-01182	CYP1A1 Protein, Human, Recombinant (His)	Human	E. coli
	CYP1A1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 63.7 kDa and the accession number is P04798.
TMPY-01329	Serpin A3c Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Serpin A3c Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P29621.
TMPY-02062	SULT1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid...
TMPK-00958	BTN1A1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Butyrophilin 1A1 (BTN1A1) is one of the membrane proteins that surrounds LD,BTN1A1 plays an important role in regulating LD synthesis via a mechanism involving membrane phospholipid composition.
TMPY-06537	BTN1A1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	BTN1A1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.96 kDa and the accession number is Q62556.
TMPY-06546	BTN1A1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	BTN1A1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.67 kDa and the accession number is Q4VAN1-1.
TMPH-01283	EEF1A1 Protein, Human, Recombinant (His)	Human	E. coli
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF...
TMPY-02461	AKR1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Aldehyde reductase (AKR1A1) is a member of the aldo-keto reductase superfamily, which consists of more than 40 known enzymes and proteins that includes variety of monomeric NADPH-dependent oxidoreductases, such as aldehy...
TMPH-03376	SULT1A1 Protein, Rat, Recombinant (His & Myc & SUMO)	Rat	E. coli
	SULT1A1 Protein, Rat, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10XHis-SUMO and C-Myc tag. The predicted molecular weight is 53.9 kDa and the accession number is P17988.
TMPJ-01281	COL21A1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one TSP N-terminal (TSPN) do...
TMPH-01284	EEF1A1 Protein, Human, Recombinant	Human	E. coli
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF...
TMPY-01583	ALDH1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has be...
TMPY-06542	BTN1A1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	BTN1A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.39 kDa and the accession number is Q4VAN1-1.
TMPH-02916	SULT1A1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	SULT1A1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.0 kDa and the accession number is P52840.
TMPH-01809	OR1A1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Odorant receptor. OR1A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 50.6 kDa and the accession number is Q9P1Q5.
TMPH-03742	EEF1A1 Protein, Cricetulus griseus, Recombinant (His)	Chinese hamster	E. coli
	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays a role in the positive regulation of IFNG transcription in T-helper 1 cells as part of an IF...
TMPY-06543	BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	BTN1A1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 27.20 kDa and the accession number is Q4VAN1-1.
TMPH-01084	CYP11A1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	CYP11A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.1 kDa and the accession number is P05108.
TMPH-01468	SLC31A1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	SLC31A1 Protein, Human, Recombinant (His & SUMO) is expressed in in vitro E. coli expression system.
TMPY-02299	ALDH3A1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (...