Powder: -20°C for 3 years | In solvent: -80°C for 1 year
4-PPBP maleate is a potent σ1 receptor (ligand) agonist. 4-PPBP maleate can be considered a selective, non-competitive NR1a/2B NMDA receptor antagonist in the context of Xenopus oocytes expression. 4-PPBP maleate has neuroprotective properties.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 16,000 | |||
10 mg | 在庫あり | ¥ 26,000 | |||
25 mg | 在庫あり | ¥ 52,500 | |||
50 mg | 在庫あり | ¥ 85,000 | |||
100 mg | 在庫あり | ¥ 126,000 | |||
500 mg | 在庫あり | ¥ 268,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 19,500 |
説明 | 4-PPBP maleate is a potent σ1 receptor (ligand) agonist. 4-PPBP maleate can be considered a selective, non-competitive NR1a/2B NMDA receptor antagonist in the context of Xenopus oocytes expression. 4-PPBP maleate has neuroprotective properties. |
In vitro | ERK1/2 phosphorylation is induced by 4-PPBP maleate in primary neurons.[3] |
In vivo | In rats, administration of 4-PPBP maleate (1 μmol/kg; i.v.) leads to a reduction in brain injury following transient focal ischemia.[2] |
分子量 | 409.52 |
分子式 | C25H31NO4 |
CAS No. | 201216-39-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: < 10.24 mg/mL
DMSO: 225.0 mg/mL (549.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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4-PPBP maleate 201216-39-9 GPCR/G Protein Neuroscience NMDAR Sigma receptor 4PPBP maleate 4-PPBP Maleate 4 PPBP maleate Inhibitor inhibitor inhibit