Powder: -20°C for 3 years | In solvent: -80°C for 1 year
6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.
説明 | 6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay. |
ターゲット&IC50 | GPR84:105 nM (EC50) |
別名 | GTPL5846 |
分子量 | 239.31 |
分子式 | C12H21N3O2 |
CAS No. | 83797-69-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (229.82 mM)
You can also refer to dose conversion for different animals. 詳細
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6-OAU 83797-69-7 Endocrinology/Hormones GPCR/G Protein GPR G protein coupled receptor 84 Inhibitor IL-8 Sf9 ERK HEK293 PMN TNF-α Lauric acid MAPKs U937 GTPL5846 GPR84 inflammation B. abortus Extracellular signal regulated kinases 6 OAU Cytokines GTPL 5846 macrophage 6OAU proinflammatory cytokine G protein-coupled receptor GTPγS GTPL-5846 chemotaxis rat air pouch model inhibit inhibitor